Doxycycline (Doxycycline Hyclate) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

Gastrointestinal: anorexia, nausea, vomiting, diarrhea, glossitis, dysphagia, enterocolitis, and inflammatory lesions (with monilial overgrowth) in the anogenital region. These reactions have been caused by both the oral and parenteral administration of tetracyclines.

Skin: Maculopapular and erythematous rashes. Exfoliative dermatitis has been reported but is uncommon. Photosensitivity is discussed above. (See WARNINGS).

Renal Toxicity: Rise in BUN has been reported and is apparently dose related. (See WARNINGS).

Hypersensitivity Reactions: urticaria, angioneurotic edema, anaphylaxis, anaphylactoid purpura, pericarditis and exacerbation of systemic lupus erythematosus.

Bulging fontanels in infants and benign intracranial hypertension in adults have been reported in individuals receiving full therapeutic dosages. These conditions disappeared rapidly when the drug was discontinued.

Blood: Hemolytic anemia, thrombocytopenia, neutropenia and eosinophilia have been reported.

When given over prolonged periods, tetracyclines have been reported to produce brown-black microscopic discoloration of thyroid glands. No abnormalities of thyroid function studies are known to occur.

REPORTS OF SUSPECTED DOXYCYCLINE SIDE EFFECTS / ADVERSE REACTIONS

Possible Doxycycline side effects / adverse reactions in 49 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2011-10-03

Patient: 49 year old female

Reactions: Oesophageal Pain, Vomiting, Dysphonia, Oesophagitis

Adverse event resulted in: hospitalization

Suspect drug(s):
Erbitux
    Indication: non-Small Cell Lung Cancer
    Start date: 2011-07-25
    End date: 2011-08-29

Taxol
    Indication: non-Small Cell Lung Cancer
    Start date: 2011-07-25
    End date: 2011-08-29

Carboplatin
    Indication: non-Small Cell Lung Cancer
    Start date: 2011-07-25
    End date: 2011-08-29

Doxycycline

Possible Doxycycline side effects / adverse reactions in 55 year old male

Reported by a physician from Germany on 2011-10-07

Patient: 55 year old male weighing 86.0 kg (189.2 pounds)

Reactions: Transaminases Increased

Suspect drug(s):
Doxycycline

Possible Doxycycline side effects / adverse reactions in 55 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2011-10-11

Patient: 55 year old male weighing 86.0 kg (189.2 pounds)

Reactions: Transaminases Increased

Suspect drug(s):
Doxycycline