NEWS HIGHLIGHTS
Published Studies Related to Dolobid (Diflunisal)
A comparison of two nonsteroidal antiinflammatory drugs (diflunisal versus dipyrone) in the treatment of moderate to severe cancer pain: a randomized crossover study. [1998.04]
The efficacy of diflunisal in cancer pain was evaluated and compared with dipyrone. Diflunisal was given at the dosage of 500 mg perorally twice a day, and dipyrone was given at the dosage of 500 mg perorally three times a day...
Clinical effects of diflunisal and paracetamol in impacted mandibular third molar surgery. [1997.09]
A double-blind, randomized, cross-over study to compare diflunisal and paracetamol for postoperative pain, swelling and trismus relief following impacted mandibular third molar surgery was designed...
Comparison of the analgesic effects of diflunisal and paracetamol in the treatment of postoperative dental pain. [1996]
The search for new effective analgesics without unwanted effects on the coagulation mechanism and a longer duration of activity has been intensified. One such development is diflunisal and the aim of this study was to compare the analgesic effect of diflunisal with that of paracetamol... The results showed a statistically significant difference in favour of diflunisal in each and every parameter used in determining the efficacy of the treatment.
Pre-operative diflunisal for pain relief following third molar surgery under general anaesthesia. [1993.04]
In order to find out whether long-acting non-narcotic analgesics given pre-operatively reduce the post-operative pain and decrease the narcotic analgesic requirements following third molar surgery under general anaesthesia, thirty Hong Kong Chinese patients undergoing this procedure were randomly given either diflunisal or placebo one hour prior to anaesthesia...
Comparative multiple-dose study of ketorolac tromethamine and diflunisal for pain following orthopaedic surgery. [1991.05]
A total of 100 patients were enrolled after orthopaedic surgery in a multiple-dose, randomized, double-blind, parallel-group study to compare the analgesic efficacy and safety of 10 mg ketorolac tromethamine given orally four times daily for 3 days with 500 mg diflunisal given orally twice daily plus placebo twice daily for 3 days.
Clinical Trials Related to Dolobid (Diflunisal)
The Effect of Diflunisal on Familial Amyloidosis [Recruiting]
The purpose of this study is to determine if diflunisal can prevent progressive lower leg
nerve damage in patients with familial amyloidosis polyneuropathy.
Study of CRx-401 on Glucose Levels in Subjects With Type II Diabetes [Recruiting]
This trial will assess the efficacy of CRx-401 in lowering FPG levels in patients taking
metformin to treat their diabetes. In addition, this initial trial will evaluate insulin
resistance (HOMA-IR index), HgbA1c levels, glycated protein, LDL, HDL, triglycerides, and
total cholesterol, as well as the safety of CRx-401.
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