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Diphenoxylate and Atropine (Diphenoxylate Hydrochloride / Atropine Sulfate) - Summary

 

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SUMMARY

DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE TABLETS, USP Cv

Each tablet, for oral administration, contains:

Diphenxylate Hydrochloride…………………………………………2.5 mg

(Warning-May be habit forming)

Atropine Sulfate..................................................................................... 0.025 mg

Diphenoxylate hydrochloride, an antidiarrheal, is ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotate monohydrochloride.

Atropine sulfate, an anticholinergic, is endo-(±)-α-(hydroxymethyl) benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1] oct-3-yl ester sulfate (2:1) (salt) monohydrate.

A subtherapeutic amount of atropine sulfate is present to discourage deliberate overdosage.

diphenoxylate and atropine (diphenoxylate/atropine) is indicated for the following:

Diphenoxylate Hydrochloride and Atropine Sulfate tablets are effective as adjunctive therapy in the management of diarrhea.

NEWS HIGHLIGHTS RELATED TO DIPHENOXYLATE AND ATROPINE

Media Articles Related to Diphenoxylate and Atropine (Diphenoxylate / Atropine)

Zinc Could Saves Lives Of Children With Diarrhea
Source: GastroIntestinal / Gastroenterology News From Medical News Today [2008.07.30]

Health Tip: Dealing With Diarrhea
Source: MedicineNet Dehydration Specialty [2008.07.17]

Inexpensive Compound Could Treat Severe Diarrhea
Source: MedicineNet E. Coli 0157:H7 Specialty [2008.06.18]

Vaccine Skin Patch Prevents Travelers' Diarrhea
Source: MedicineNet Travel Medicine Specialty [2008.06.12]

Salix Presents New Rifaximin Phase IIb Data Demonstrating Significant And Sustained Improvement In Diarrhea-Associated Irritable Bowel Syndrome
Source: Irritable-Bowel Syndrome News From Medical News Today [2008.05.21]

more>>

Published Studies Related to Diphenoxylate and Atropine (Diphenoxylate / Atropine)

Are one or two dangerous? Diphenoxylate-atropine exposure in toddlers. [2008.01]

Diphenoxylate-atropine (Lomotil) overdose in children: an update (report of eight cases and review of the literature) [1991.05]

Effect of liquid diphenoxylate hydrochloride and atropine sulfate (Lomotil) instillations on dynamics and function of continent cecal urinary reservoirs. [1987.10]

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Clinical Trials Related to Diphenoxylate and Atropine (Diphenoxylate / Atropine)

Diphenoxylate / Atropine to Decrease FDG Activity During F-18 FDG PET [Completed]

LOSS- Louisiana Obese Subjects Study [Active, not recruiting]

Study to Evaluate the Likeability, Safety, and Abuse Potential of NRP 104 in Adults With Histories of Stimulant Abuse [Completed]

more>>

Page last updated: 2008-07-30

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