Diphenhydramine (Diphenhydramine Hydrochloride) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

The most frequent adverse reactions are underscored.

1. General: Urticaria, drug rash, anaphylactic shock, photosensitivity, excessive perspiration, chills, dryness of mouth, nose, and throat
2. Cardiovascular System: Hypotension, headache, palpitations, tachycardia, extrasystoles
3. Hematologic: Hemolytic anemia, thrombocytopenia, agranulocytosis
4. Nervous System: Sedation sleepiness, dizziness, disturbed coordination, fatigue, confusion, restlessness, excitation, nervousness, tremor, irritability, insomnia, euphoria, paresthesia, blurred vision, diplopia, vertigo, tinnitus, acute labyrinthitis, neuritis, convulsions
5. GI System: Epigastric distress, anorexia, nausea, vomiting, diarrhea, constipation
6. GU System: Urinary frequency, difficult urination, urinary retention, early menses
7. Respiratory System: Thickening of bronchial secretions, tightness of chest or throat and wheezing, nasal stuffiness.