Dipentum (Olsalazine Sodium) - Summary

DIPENTUM SUMMARY

DIPENTUM
(olsalazine sodium capsules)

The active ingredient in DIPENTUM Capsules (olsalazine sodium) is the sodium salt of a salicylate, disodium 3,3'-azobis (6-hydroxybenzoate) a compound that is effectively bioconverted to 5-aminosalicylic acid (5-ASA), which has anti-inflammatory activity in ulcerative colitis.

Olsalazine is indicated for the maintenance of remission of ulcerative colitis in patients who are intolerant of sulfasalazine.

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DIPENTUM NEWS HIGHLIGHTS

Published Studies Related to Dipentum (Olsalazine)

A prospective randomized observer-blind 2-year trial of azathioprine monotherapy versus azathioprine and olsalazine for the maintenance of remission of steroid-dependent ulcerative colitis. [2004.06]

Olsalazine is not superior to placebo in maintaining remission of inactive Crohn's colitis and ileocolitis: a double blind, parallel, randomised, multicentre study. [2001.10]

The systemic load and efficient delivery of active 5-aminosalicylic acid in patients with ulcerative colitis on treatment with olsalazine or mesalazine. [1999.03]

Olsalazine versus mesalazine in the treatment of mild to moderate ulcerative colitis. [1998.08]

Systemic absorption of 5-aminosalicylic acid in patients with inactive ulcerative colitis treated with olsalazine and mesalazine. [1996.11]

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Clinical Trials Related to Dipentum (Olsalazine)

Phase II Pilot Study of Olsalazine for Ankylosing Spondylitis [Completed]

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