Diovan (Valsartan) - Description

T2000-31

89004202

      Diovan ^®

      valsartan  

      Capsules

      Rx only

      Prescribing Information

DESCRIPTION

Diovan (valsartan) is a nonpeptide, orally active, and specific angiotensin II antagonist acting on the AT₁ receptor subtype.

      Valsartan is chemically described as N -(1-oxopentyl)- N -[[2′-(1 H -tetrazol-5-yl) [1,1′-biphenyl]-4-yl]methyl]-L-valine. Its empirical formula is C₂₄H₂₉N₅O₃,its molecular weight is 435.5, and its structural formula is

      Valsartan is a white to practically white fine powder. It is soluble in ethanol and methanol and slightly soluble in water.

      Diovan is available as capsules for oral administration, containing either 80 mg or 160 mg of valsartan. The inactive ingredients of the capsules are cellulose compounds, crospovidone, gelatin, iron oxides, magnesium stearate, povidone, sodium lauryl sulfate, and titanium dioxide.