Diovan (Valsartan) - Summary

DIOVAN SUMMARY

Diovan^®

Diovan® (valsartan) is a nonpeptide, orally active, and specific angiotensin II antagonist acting on the AT₁ receptor subtype.

Diovan® (valsartan) is indicated for the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents.

Diovan is indicated for the treatment of heart failure (NYHA class II-IV) in patients who are intolerant of angiotensin converting enzyme inhibitors. In a controlled clinical trial, Diovan significantly reduced hospitalizations for heart failure. There is no evidence that Diovan provides added benefits when it is used with an adequate dose of an ACE inhibitor.

DIOVAN NEWS HIGHLIGHTS

Media Articles Related to Diovan (Valsartan)

Single Pill Combinations Diovan HCT® And Exforge® Approved In US As First-line Treatments For High Blood Pressure
Source: Hypertension News From Medical News Today [2008.08.09]

Single-Pill Combinations Diovan HCT And Exforge Approved In US As First-Line Treatments For High Blood Pressure
Source: Hypertension News From Medical News Today [2008.08.05]

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Published Studies Related to Diovan (Valsartan)

Randomized, Double-blinded Trial Evaluation of Valsartan/Hydrochlorothiazide Combination Therapy in Mild to Moderate Essential Hypertension in North-east China. [2008.07]

Valsartan improves arterial stiffness in type 2 diabetes independently of blood pressure lowering. [2008.06]

[Valsartan improves symptoms and quality of life in patients with chronic heart failure] [2008.04.10]

High-risk myocardial infarction in the young: the VALsartan In Acute myocardial iNfarcTion (VALIANT) trial. [2008.04]

Effect of valsartan compared with valsartan/hydrochlorothiazide on plasma levels of cellular adhesion molecules: the Val-MARC trial. [2008.03]

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Clinical Trials Related to Diovan (Valsartan)

A Safety and Tolerability Study of the Combination of Aliskiren/Valsartan in Patients With High Blood Pressure, Followed by Long-Term Safety and Tolerability of Aliskiren, Valsartan and Hydrochlorothiazide. [Active, not recruiting]

A Study in Chinese Mild to Moderate Hypertensive Patients Comparing the Efficacy of Co-Diovan With Diovan. [Completed]

To Compare the Blood Level of Marketed Japanese Valsartan Tablet Formulation vs Global Valsartan Tablet Formulation in Healthy Volunteers [Completed]

8-Week Study to Evaluate Safety and Efficacy of Various Combinations of Valsartan, HCTZ, and Amlodipine in Patients With Moderate to Severe Hypertension [Completed]

Bioavailability of Aliskiren and Valsartan Combined as a Single Tablet vs. the Same Medications Given Separately to Healthy Subjects. [Completed]

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