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Diovan HCT (Valsartan / Hydrochlorothiazide) - Summary

 


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USE IN PREGNANCY

When used in pregnanc y, drugs that ac t directly on the re nin-angiotensin system can cause injury and even death to the developing fetus. When pregnancy is detected, Diovan HCT should be discontinued as soon as possible.   See WARNINGS: Fetal/Neonatal Morbidity and Mortality.

 

DIOVAN HCT SUMMARY

Diovan HCT®

Diovan HCT® (valsartan and hydrochlorothiazide, USP) is a combination of valsartan, an orally active, specific angiotensin II antagonist acting on the AT1 receptor subtype, and hydrochlorothiazide, a diuretic.

Diovan HCT® (valsartan and hydrochlorothiazide, USP) is indicated for the treatment of hypertension. This fixed dose combination is not indicated for initial therapy (see DOSAGE AND ADMINISTRATION).
See all Diovan HCT indications & dosage >>

DIOVAN HCT NEWS HIGHLIGHTS

Media Articles Related to Diovan HCT (Valsartan / Hydrochlorothiazide)

International Medical Team Announces Patient Results In Adult Stem Cell Clinical Study For Pulmonary Hypertension
Source: Cardiovascular / Cardiology News From Medical News Today [2008.11.27]

Why Does It Take So Long For A Correct Diagnosis Of Pulmonary Hypertension?
Source: Respiratory / Asthma News From Medical News Today [2008.11.26]

Hypertension May Hit Black Males Earlier
Source: MedicineNet Exercise and Activity Specialty [2008.11.25]

Office Blood Pressure Measurement Useless in Patients with Resistant Hypertension
Source: MedPage Today Cardiovascular [2008.11.24]

Hypertension Develops Early, Silently, In African-American Men
Source: Hypertension News From Medical News Today [2008.11.18]

more >>

Published Studies Related to Diovan HCT (Valsartan / Hydrochlorothiazide)

Randomized, Double-blinded Trial Evaluation of Valsartan/Hydrochlorothiazide Combination Therapy in Mild to Moderate Essential Hypertension in North-east China. [2008.07]

Combination therapy with valsartan/hydrochlorothiazide at doses up to 320/25 mg improves blood pressure levels in patients with hypertension inadequately controlled by valsartan 320 mg monotherapy. [2008.06]

Combination therapy with valsartan/hydrochlorothiazide at doses up to 320/25 mg improves blood pressure levels in patients with hypertension inadequately controlled by valsartan 320 mg monotherapy. [2008.01.24]

[Therapeutic efficacy of valsartan and valsartan/HCTZ in mild to moderate hypertensive patients] [2007.08]

Aliskiren, an orally effective Renin inhibitor, provides antihypertensive efficacy alone and in combination with valsartan. [2007.01]

more >>

Clinical Trials Related to Diovan HCT (Valsartan / Hydrochlorothiazide)

A Safety and Tolerability Study of the Combination of Aliskiren/Valsartan in Patients With High Blood Pressure, Followed by Long-Term Safety and Tolerability of Aliskiren, Valsartan and Hydrochlorothiazide. [Active, not recruiting]

A Study in Chinese Mild to Moderate Hypertensive Patients Comparing the Efficacy of Co-Diovan With Diovan. [Completed]

To Compare the Blood Level of Marketed Japanese Valsartan Tablet Formulation vs Global Valsartan Tablet Formulation in Healthy Volunteers [Completed]

8-Week Study to Evaluate Safety and Efficacy of Various Combinations of Valsartan, HCTZ, and Amlodipine in Patients With Moderate to Severe Hypertension [Completed]

Bioavailability of Aliskiren and Valsartan Combined as a Single Tablet vs. the Same Medications Given Separately to Healthy Subjects. [Completed]

more >>

Page last updated: 2008-11-27

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