Differin (Adapalene) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

Some adverse effects such as erythema, scaling, dryness, pruritus, and burning will occur in 10-40% of patients. Pruritus or burning immediately after application also occurs in approximately 20% of patients. The following additional adverse experiences were reported in approximately 1% or less of patients: skin irritation, burning/stinging, erythema, sunburn, and acne flares. These are most commonly seen during the first month of therapy and decrease in frequency and severity thereafter. All adverse effects with use of DIFFERIN Gel during clinical trials were reversible upon discontinuation of therapy.

REPORTS OF SIDE EFFECTS / ADVERSE REACTIONS RELATED TO DIFFERIN

Possible Differin side effects / adverse reactions in 21 year old female

Reported by a physician from Canada on 2007-02-22

Patient: 21 year old female

Reactions: Thyroid Cancer

Suspect drug(s):
Differin
    Start date: 2000-05-01
    End date: 2000-05-01

Differin
    Start date: 2005-02-01

Proactiv
    Indication: Acne

Tetracycline
    Indication: Acne

T-Stat Pads
    Indication: Acne

Stievamycin
    Indication: Acne

OXY
    Indication: Acne

Persa-Gel W
    Indication: Acne

Spectro Gel
    Indication: Acne

Erypak
    Indication: Acne
    Start date: 1999-11-01

Solugel /tun/
    Indication: Acne
    Start date: 1999-11-01

Solugel /tun/
    Indication: Acne
    Start date: 2000-07-01

Alesse
    Indication: Contraception
    Start date: 2000-07-01

Clindamycin
    Indication: Acne

Possible Differin side effects / adverse reactions in 24 year old female

Reported by a physician from United States on 2007-03-12

Patient: 24 year old female weighing 56.7 kg (124.7 pounds)

Reactions: LIP Swelling, Hypoaesthesia Oral, Syncope, Dizziness, Enterocolitis, Muscle Spasms

Suspect drug(s):
Differin
    Dosage: 1 app qd tp
    Indication: Acne
    Start date: 2007-02-02
    End date: 2007-02-04

Benzaclin
    Start date: 2007-02-02
    End date: 2007-02-05

Other drugs received by patient: Lexapro; Yasmin