Differin Related Published Studies
Well-designed clinical trials related to Differin (Adapalene)
A North American study of adapalene-benzoyl peroxide combination gel in the treatment of acne. [2009.08]
Adapalene-benzoyl peroxide, a unique fixed-dose combination topical gel for the treatment of acne vulgaris: a transatlantic, randomized, double-blind, controlled study in 1670 patients. [2009.05.21]
Tolerability of clindamycin/tretinoin gel vs. tretinoin microsphere gel and adapalene gel. [2009.04]
Prospective, open-label, comparative study of clindamycin 1%/benzoyl peroxide 5% gel with adapalene 0.1% gel in Asian acne patients: efficacy and tolerability. [2009.03]
Adapalene 0.1% and benzoyl peroxide 2.5% as a fixed-dose combination gel is as well tolerated as the individual components alone in terms of cumulative irritancy. [2008.09]
Long-term safety and efficacy study of adapalene 0.3% gel. [2008.06]
Adapalene-benzoyl peroxide, a fixed-dose combination for the treatment of acne vulgaris: results of a multicenter, randomized double-blind, controlled study. [2007.11]
Adapalene-benzoyl peroxide, a fixed-dose combination for the treatment of acne vulgaris: Results of a multicenter, randomized double-blind, controlled study. [2007.07.24]
Community-based trial results of combination clindamycin 1%--benzoyl peroxide 5% topical gel plus tretinoin microsphere gel 0.04% or 0.1% or adapalene gel 0.1% in the treatment of moderate to severe acne. [2007.07]
Tolerability comparison of adapalene gel, 0.3% versus tazarotene cream, 0.05% in subjects with healthy skin. [2007.06]
Study results of benzoyl peroxide 5%/clindamycin 1% topical gel, adapalene 0.1% gel, and use in combination for acne vulgaris. [2007.06]
Adapalene gel, 0.1%, as maintenance therapy for acne vulgaris: a randomized, controlled, investigator-blind follow-up of a recent combination study. [2006.05]
Adapalene gel 0.3% for the treatment of acne vulgaris: a multicenter, randomized, double-blind, controlled, phase III trial. [2006.02]
The efficacy and safety of adapalene gel 0.3% in the treatment of acne vulgaris: A randomized, multicenter, investigator-blinded, controlled comparison study versus adapalene gel 0.1% and vehicle. [2005.08]
Combination therapy with adapalene gel 0.1% and doxycycline for severe acne vulgaris: a multicenter, investigator-blind, randomized, controlled study. [2005.05]
Cumulative irritation potential of adapalene 0.1% cream and gel compared with tretinoin microsphere 0.04% and 0.1%. [2005.04]
Benzoyl peroxide, adapalene, and their combination in the treatment of acne vulgaris. [2005.03]
Adapalene vs. metronidazole gel for the treatment of rosacea. [2005.03]
Tazarotene cream versus adapalene cream in the treatment of facial acne vulgaris: a multicenter, double-blind, randomized, parallel-group study. [2005.03]
A successful maintenance approach in inflammatory acne with adapalene gel 0.1% after an initial treatment in combination with clindamycin topical solution 1% or after monotherapy with clindamycin topical solution 1%. [2004.12]
Skin tolerability and efficacy of combination therapy with hydrogen peroxide stabilized cream and adapalene gel in comparison with benzoyl peroxide cream and adapalene gel in common acne. A randomized, investigator-masked, controlled trial. [2004.08]
Cumulative irritancy potential of adapalene cream 0.1% compared with adapalene gel 0.1% and several tretinoin formulations. [2003.12]
Cumulative irritancy comparison of adapalene gel 0.1% versus other retinoid products when applied in combination with topical antimicrobial agents. [2003.09]
Is combined oral and topical therapy better than oral therapy alone in patients with moderate to moderately severe acne vulgaris? A comparison of the efficacy and safety of lymecycline plus adapalene gel 0.1%, versus lymecycline plus gel vehicle. [2003.09]
Efficacy and tolerability of combined topical treatment of acne vulgaris with adapalene and clindamycin: a multicenter, randomized, investigator-blinded study. [2003.09]
Cumulative irritation comparison of adapalene gel and solution with 2 tazarotene gels and 3 tretinoin formulations. [2003.07]
Assessment of adapalene gel for the treatment of actinic keratoses and lentigines: a randomized trial. [2003.07]
Topical adapalene gel 0.1% vs. isotretinoin gel 0.05% in the treatment of acne vulgaris: a randomized open-label clinical trial. [2002.09]
Randomised, controlled trial of the efficacy and safety of adapalene gel 0.1% and tretinoin cream 0.05% in patients with acne vulgaris. [2002.07]
A multicenter, double-blind, randomized comparison study of the efficacy and tolerability of once-daily tazarotene 0.1% gel and adapalene 0.1% gel for the treatment of facial acne vulgaris. [2002.02]
Adapalene gel 0.1%: effective and well tolerated in the topical treatment of acne vulgaris in Chinese patients. [2001.10]
Efficacy and tolerance of adapalene cream 0.1% compared with its cream vehicle for the treatment of acne vulgaris. [2001.10]
Randomized, controlled, bilateral (split-face) comparison trial of the tolerability and patient preference of adapalene gel 0.1% and tretinoin microsphere gel 0.1% for the treatment of acne vulgaris. [2001.10]
Randomized controlled trial of the tolerability, safety, and efficacy of adapalene gel 0.1% and tretinoin microsphere gel 0.1% for the treatment of acne vulgaris. [2001.10]
Comparison of treatment of acne vulgaris with alternate-day applications of tazarotene 0.1% gel and once-daily applications of adapalene 0.1% gel: a randomized trial. [2001.06]
Comparison of the cumulative irritation potential of adapalene gel and cream with that of erythromycin/tretinoin solution and gel and erythromycin/isotretinoin gel. [2001.02]
A comparison of adapalene gel 0.1% vs. tretinoin gel 0.025% in the treatment of acne vulgaris in China. [2001]
Split-face clinical and bio-instrumental comparison of 0.1% adapalene and 0.05% tretinoin in facial acne. [1999]
Comparison of adapalene 0.1% solution and tretinoin 0.025% gel in the topical treatment of acne vulgaris. [1998.10]
Comparative tolerance of adapalene 0.1% gel and six different tretinoin formulations. [1998.10]
Evaluation of clinical efficacy and safety of adapalene 0.1% gel versus tretinoin 0.025% gel in the treatment of acne vulgaris, with particular reference to the onset of action and impact on quality of life. [1998.10]
Adapalene 0.1% gel has low skin irritation potential even when applied immediately after washing. [1998.10]
Adapalene 0.1% gel and adapalene 0.1% cream stimulate retinoic acid receptor mediated gene transcription without significant irritative effects in the skin of healthy human volunteers. [1998.10]
Clinical efficacy and safety comparison of adapalene gel and tretinoin gel in the treatment of acne vulgaris: Europe and U.S. multicenter trials. [1997.06]
Adapalene 0.1% gel is better tolerated than tretinoin 0.025% gel in acne patients. [1997.06]
Skin tolerance of adapalene 0.1% gel in combination with other topical antiacne treatments. [1997.06]
Adapalene 0.1% gel has low skin-irritation potential. [1997.06]
A comparison of the efficacy and safety of adapalene gel 0.1% and tretinoin gel 0.025% in the treatment of acne vulgaris: a multicenter trial. [1996.03]
[Comparative study of the efficacy and tolerability of 0.1 and 0.03 p.100 adapalene gel and 0.025 p.100 tretinoin gel in the treatment of acne] [1996]
Comparison of CD271 (adapalene) and all-trans retinoic acid in human skin: dissociation of epidermal effects and CRABP-II mRNA expression. [1993.09]
Well-designed clinical trials possibly related to Differin (Adapalene)
Oral isotretinoin is as effective as a combination of oral isotretinoin and topical anti-acne agents in nodulocystic acne. [2008.03]
Efficacy and safety of serial glycolic acid peels and a topical regimen in the treatment of recalcitrant melasma. [2007.01]
Clinical experience results with clindamycin 1% benzoyl peroxide 5% gel (Duac) as monotherapy and in combination. [2005.03]
Facial tolerability of topical retinoid therapy. [2004.11]
[The clinical observation of treating acne vulgaris with "xiao cuo fang"] [2004.04]
A comparative trial of two retinoids commonly used in the treatment of acne vulgaris. [2001.09]
Lipid analysis of follicular casts from cyanoacrylate strips as a new method for studying therapeutic effects of antiacne agents. [2001.07]
Comparative irritancy study among retinoid creams and gels. [1999.10]
Efficacy and safety of CD 271 alcoholic gels in the topical treatment of acne vulgaris. [1991.04]
Other research related to Differin (Adapalene)
Adapalene 0.1% and benzoyl peroxide 2.5%: a novel combination for treatment of acne vulgaris. [2009.07]
Adapalene gel 0.1% is better tolerated than tretinoin gel 0.025% among healthy volunteers of various ethnic origins. [2009.01.01]
A review of adapalene in the treatment of acne vulgaris. [2008.11]
Adapalene 0.1% gel compared to tazarotene 0.1% cream in the treatment of acne vulgaris. [2008.06]
Efficacy and tolerability of adapalene 0.3% gel compared to tazarotene 0.1% gel in the treatment of acne vulgaris. [2008.06]
Adapalene gel 0.1% in the treatment of infantile acne: an open clinical study. [2008.05]
Adapalene gel 0.1% is effective and safe for Japanese patients with acne vulgaris: a randomized, multicenter, investigator-blinded, controlled study. [2008.03]
Adapalene-benzoyl peroxide once-daily, fixed-dose combination gel for the treatment of acne vulgaris: a randomized, bilateral (split-face), dose-assessment study of cutaneous tolerability in healthy participants. [2008.03]
A randomized, single-blind comparison of topical clindamycin + benzoyl peroxide and adapalene in the treatment of mild to moderate facial acne vulgaris. [2008.01]
Adapalene gel 0.1% is effective and safe for Japanese patients with acne vulgaris: A randomized, multicenter, investigator-blinded, controlled study. [2007.12.04]
Long-term safety and efficacy of a unique fixed-dose combination gel of adapalene 0.1% and benzoyl peroxide 2.5% for the treatment of acne vulgaris. [2007.09]
Adapalene pretreatment increases follicular penetration of clindamycin: in vitro and in vivo studies. [2007.09]
Control of microcomedone formation throughout a maintenance treatment with adapalene gel, 0.1%. [2007.07]
Daily treatment with adapalene gel 0.1% maintains initial improvement of acne vulgaris previously treated with oral lymecycline. [2007.01]
Treatment considerations for inflammatory acne: clinical evidence for adapalene 0.1% in combination therapies. [2006.09]
Subject preferences for acne treatments containing adapalene gel 0.1%: results of the MORE trial. [2006.07]
The MORE trial: effectiveness of adapalene gel 0.1% in real-world dermatology practices. [2006.07]
Anti-inflammatory effects of tretinoin (all-trans-retinoic acid) 0.1% and adapalene 0.1% in rats. [2005.09]
Cumulative irritation potential of adapalene 0.1% cream and gel compared with tazarotene cream 0.05% and 0.1%. [2005.05]
Topical tretinoin or adapalene in acne vulgaris: an overview. [2004.07]
Phototoxic effects of topical azelaic acid, benzoyl peroxide and adapalene were not detected when applied immediately before UVB to normal skin. [2004.07]
Spotlight on adapalene in acne vulgaris. [2004]
Adapalene: a review of its use in the treatment of acne vulgaris. [2004]
Single-blind and comparative clinical study of the efficacy and safety of benzoyl peroxide 4% gel (BID) and adapalene 0.1% Gel (QD) in the treatment of acne vulgaris for 11 weeks. [2003.09]
Efficacy and cutaneous safety of adapalene in black patients versus white patients with acne vulgaris. [2002.10]
Adapalene gel 0.1% for topical treatment of acne vulgaris in African patients. [2001.10]
Adapalene gel 0.1% is effective and well tolerated in acne patients in a dermatology practice setting. [2001.10]
Polarized light photography and videomicroscopy greatly enhance the capability of estimating the therapeuic response to a topical retinoid (adapalene) in acne vulgaris. [2001.10]
Adapalene biochemistry and the evolution of a new topical retinoid for treatment of acne. [2001]
Adapalene in the treatment of African patients. [2001]
An update of recent clinical trials examining adapalene and acne. [2001]
Pivotal clinical trials of adapalene in the treatment of acne. [2001]
Adapalene: an update on newer comparative studies between the various retinoids. [2000.10]
Effective treatment of localized Darier's disease with adapalene 0.1% gel. [1999.04]
A comparison of the efficacy and tolerability of adapalene 0.1% gel versus tretinoin 0.025% gel in patients with acne vulgaris: a meta-analysis of five randomized trials. [1998.10]
[Pharma-Clinics. The drug of the month. Adapalene (Differin gel)] [1998.02]
Skin distribution and pharmaceutical aspects of adapalene gel. [1997.06]
Adapalene. A review of its pharmacological properties and clinical potential in the management of mild to moderate acne. [1997.03]
Adapalene, a new chemical entity with retinoid activity. [1993]
Other possibly related research studies
Mechanisms of the comedolytic and anti-inflammatory properties of topical retinoids. [2005.01]
Meta-analysis of topical tazarotene in the treatment of mild to moderate acne. [2004.10]
Axillary granular parakeratosis. [2003.07]
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