DICYCLOMINE SUMMARY
DICYCLOMINE HYDROCHLORIDE TABLETS, USP
Dicyclomine hydrochloride is an antispasmodic and anticholinergic (antimuscarinic) agent.
Dicyclomine hydrochloride is indicated for the treatment of functional bowel/irritable bowel syndrome.
|
NEWS HIGHLIGHTSMedia Articles Related to Dicyclomine
Lexicon Announces Positive Phase 2 Results Of LX1031 In Non-Constipating Irritable Bowel Syndrome
Source: GastroIntestinal / Gastroenterology News From Medical News Today [2009.11.13]
Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) announced that the company's investigational new drug, LX1031, a tryptophan hydroxylase (TPH) inhibitor, demonstrated positive results in clinically important parameters for the treatment of non-constipating irritable bowel syndrome (IBS).
Pharmos Announces Results Of Phase 2b Irritable Bowel Syndrome Study
Source: Irritable-Bowel Syndrome News From Medical News Today [2009.09.15]
Pharmos Corporation (Pink Sheets: PARS) announced the results of its Phase 2b Dextofisopam clinical trial to evaluate safety and efficacy of the compound in irritable bowel syndrome. Although the primary efficacy variable (% of weeks responding for adequate overall relief of IBS symptoms) did not reach statistical significance, the percentage responding for the Dextofisopam 200 mg group was higher than that observed for the Phase 2a trial.
Contrary To Insoluble Fiber, Soluble Fiber Is An Effective Treatment For Irritable Bowel Syndrome
Source: Irritable-Bowel Syndrome News From Medical News Today [2009.08.28]
The first trial in increasing dietary fiber in a primary care setting is published on bmj.com today. It reports that soluble fiber (psyllium) is an effective treatment for irritable bowel syndrome (IBS). On the other hand, insoluble fiber such as bran may worsen symptoms. Irritable bowel syndrome is characterized by abdominal pain and an irregular bowel habit. It affects about 10 percent of the population.
Alternative Treatment For Irritable Bowel Syndrome When Conventional Therapy Has Failed
Source: Irritable-Bowel Syndrome News From Medical News Today [2009.08.13]
IBS remains a common intestinal disorder causing significant discomfort and poor quality of life in patients who have the diagnosis. TCAs have been shown to improve abdominal pain in patients with IBS; however, there is insufficient evidence of global symptom relief. The search for an optimal treatment to improve symptoms and quality of life in IBS remains ongoing. A research article published in the World Journal of Gastroenterology addresses this problem.
Is Somatic Hypersensitivity A Predictor Of Irritable Bowel Syndrome?
Source: Irritable-Bowel Syndrome News From Medical News Today [2009.07.23]
Although visceral hypersensitivity is considered a hallmark feature of IBS, conflicting evidence exists regarding somatic hypersensitivity in this patient population. Several investigators have found no evidence for heightened somatic pain sensitivity in IBS patients. Also, others have reported similar cold presser pain tolerance in IBS patients and controls. These conflicting findings may result from differing somatic pain testing procedures.
|
PATIENT REVIEWS / RATINGS / COMMENTSBased on a total of 2 ratings/reviews, Dicyclomine has an overall score of 7. The effectiveness score is 6 and the side effect score is 8. The scores are on ten point scale: 10 - best, 1 - worst.
| | Dicyclomine review by 48 year old female patient | | | Rating |
| Overall rating: | |   |
| Effectiveness: | | Moderately Effective |
| Side effects: | | Mild Side Effects | | |
Treatment Info |
| Condition / reason: | | ibs |
| Dosage & duration: | | 4xa day (dosage frequency: 1x a day) for the period of 4 months |
| Other conditions: | | anxiety,panic, depression |
| Other drugs taken: | | b/c pill, ritalin | | |
Reported Results |
| Benefits: | | helps with ibs-c |
| Side effects: | | slightly "drugged" feeling, went away after a few days |
| Comments: | | supposed to take one tablet before each meal and one at bedtime. i take only one at bedtime and have still had considerable success w/ibs symptoms. i also supplement with acacia powder, apple cider vinegar, acidophilus supplements, and magnesium supplements. |
|
| | Dicyclomine review by 48 year old female patient | | | Rating |
| Overall rating: | | |
| Effectiveness: | | Moderately Effective |
| Side effects: | | Mild Side Effects | | |
Treatment Info |
| Condition / reason: | | ibs |
| Dosage & duration: | | 4xa day (dosage frequency: 1x a day) for the period of 4 months |
| Other conditions: | | anxiety,panic, depression |
| Other drugs taken: | | b/c pill, ritalin | | |
Reported Results |
| Benefits: | | helps with ibs-c |
| Side effects: | | slightly "drugged" feeling, went away after a few days |
| Comments: | | supposed to take one tablet before each meal and one at bedtime. i take only one at bedtime and have still had considerable success w/ibs symptoms. i also supplement with acacia powder, apple cider vinegar, acidophilus supplements, and magnesium supplements. |
|
|
|
Page last updated: 2009-11-13
|
