|
DRUG INTERACTIONS
DEXAMETHASONE drug label information in our database does not contain a dedicated section on drug interactions. Please check subsections of WARNINGS AND PRECAUTIONS as well as other sources.
|
OVERDOSAGE
Reports of acute toxicity and/or death following overdosage of glucocorticoids are rare. In the event of overdosage, no specific antidote is available; treatment is supportive and symptomatic.
The oral LD50 of dexamethasone in female mice was 6.5 g/kg. The intravenous LD50 of dexamethasone sodium phosphate in female mice was 794 mg/kg.
|
CONTRAINDICATIONS
Systemic fungal infections (see
WARNINGS
regarding amphotericin B).
Hypersensitivity to any component of this product (see
WARNINGS
)
.
|
REFERENCES
- Cavanagh, D.; Singh, K.B.: Endotoxin shock in pregnancy and abortion, in: “Corticosteroids in the Treatment of Shock”, Schumer, W.; Nyhus, L.M., Editors, Urbana, University of Illinois Press, 1970, pp. 86-96.
- Dietzman, R.H.; Ersek, R.A.; Bloch, J.M.; Lilleheir, R.C.: High-output, low-resistance gram-negative septic shock in man, Angiology
20
: 691-700, Dec. 1969.
- Frank, E.: Clinical observations in shock and management (in: Shields, T.F., ed.: Symposium on current concepts and management of shock), J. Maine Med. Ass.
59
: 195-200, Oct. 1968.
- Oaks, W. W.; Cohen, H.E.: Endotoxin shock in the geriatric patient, Geriat.
22
: 120-130, Mar. 1967.
- Schumer, W.; Nyhus, L.M.: Corticosteroid effect on biochemical parameters of human oligemic shock, Arch. Surg.
100
: 405-408, Apr. 1970.
45955D
Revised: April 2008
|
|
|
-- advertisement --
|