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Desonide (Desonide Topical) - Summary

 



DESONIDE SUMMARY

DESONIDE OINTMENT, 0.05%

Desonide Ointment, 0.05% contains microdispersed desonide (the active ingredient) in white petrolatum. Each gram of desonide ointment contains 0.5 milligrams of desonide. Desonide Ointment is applied topically. Desonide is a non-fluorinated corticosteroid.

Topical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.


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NEWS HIGHLIGHTS

Media Articles Related to Desonide (Desonide Topical)

ACAAI: Combo Beats Budesonide Alone in Asthma (CME/CE)
Source: MedPage Today Allergy & Immunology [2009.11.12]
MIAMI BEACH (MedPage Today) -- Regardless of the asthma patient's age, treatment with a combination of budesonide and formoterol produced a greater improvement in lung function than budesonide pressurized metered-dose inhalers alone, researchers reported here.

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Published Studies Related to Desonide (Desonide Topical)

Safety and efficacy of desonide hydrogel 0.05% in pediatric subjects with atopic dermatitis. [2007.02]
Low to mid potency corticosteroids remain a cornerstone of therapy for atopic dermatitis (AD)...

Corneofungimetry bioassay on Malassezia spp. under ketoconazole and desonide influences. [2005.03]
CONCLUSION: The presence of 0.05% desonide does not impair or improve the Malassezia susceptibility to 2% ketoconazole when growing on lipid-enriched human stratum corneum. Copyright 2005 S. Karger AG, Basel.

Desonide foam 0.05%: safety in children as young as 3 months. [2008.08]
BACKGROUND: Desonide 0.05% was recently developed in an emulsion foam formulation. OBJECTIVE: The safety of desonide foam 0.05% in children aged 3 months to 17 years was evaluated in two phase II studies and one phase III study... CONCLUSION: Desonide foam was safe and well tolerated in participants as young as 3 months.

Desonide: a review of formulations, efficacy and safety. [2008.07]
BACKGROUND: Desonide is a low-potency topical corticosteroid that has been used for decades in the treatment of steroid-responsive dermatoses. The favorable safety profile of this topical agent makes it ideal for patients of all ages. OBJECTIVE: This article provides a review of desonide's history, pharmacodynamic properties, vehicle technology, efficacy and safety... CONCLUSION: Clinical efficacy and safety have been proven in multiple clinical trials. In addition to cream, lotion and ointment formulations, the recently developed hydrogel and foam preparations have increased desonide's versatility and patient tolerability.

Desonide foam: a review. [2008.01]
Desonide foam is a newly approved topical corticosteroid preparation of 0.05% desonide. It has been shown effective compared with vehicle placebo in the treatment of mild-to-moderate atopic dermatitis in both pediatric and adult populations.

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Clinical Trials Related to Desonide (Desonide Topical)

Efficacy of Desonide (Desonatetm) Gel 0.05% in Younger and Older Subjects With Atopic Dermatitis [Active, not recruiting]
The purpose of this research study is to better understand how this study drug works when people use it to treat atopic dermatitis. Desonate has been approved by the US Food and Drug Administration (FDA) for atopic dermatitis.

Comparison of the Efficacy and Safety of Two Topical Creams for Pediatric Atopic Dermatitis [Not yet recruiting]
This study compares the effectiveness of two topical creams for atopic dermatitis in pediatric subjects. Subjects will be randomly assigned to use one of the two creams twice daily for 6 weeks or until clear.

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PATIENT REVIEWS / RATINGS / COMMENTS

Based on a total of 1 ratings/reviews, Desonide has an overall score of 4. The effectiveness score is 6 and the side effect score is 6. The scores are on ten point scale: 10 - best, 1 - worst.
 

Desonide review by 29 year old female patient

  Rating
Overall rating:  
Effectiveness:   Moderately Effective
Side effects:   Moderate Side Effects
  
Treatment Info
Condition / reason:   exzema of the face
Dosage & duration:   0.05% (dosage frequency: up to three times daily) for the period of up to 6 months
Other conditions:   none. just skin irritations
Other drugs taken:   none
  
Reported Results
Benefits:   the treatment benefits was that the skin irritation did go away for awhile. I thought that I had been cured of the skin rash. It cleared my skin up and gave me relief from the rash.
Side effects:   It turns out it did not cure it at all but possibly hurt my face. It also may have made the condition spread to other areas of my face because in time I had other areas of my face where the rash was. The cream was only a temporary relief to a deeper situation. If one is looking for fast relief it will help but it covers up an initial problem that needs to be addressed.
Comments:   I saw a few dermatologists and each one told me to use it twice daily. I was even given different forms. One a cream and the other a foam. I was also informed to use them for two weeks and then stop. I did, and when I stopped my rash slowly started coming back.

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Page last updated: 2009-11-12

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