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Depo-Testosterone (Testosterone Cypionate) - Summary

 
 



SUMMARY

DEPO-Testosterone Injection, for intramuscular injection, contains testosterone cypionate which is the oil-soluble 17 (beta)- cyclopentylpropionate ester of the androgenic hormone testosterone. Testosterone cypionate is a white or creamy white crystalline powder, odorless or nearly so and stable in air. It is insoluble in water, freely soluble in alcohol, chloroform, dioxane, ether, and soluble in vegetable oils.

DEPO-Testosterone Injection is indicated for replacement therapy in the male in conditions associated with symptoms of deficiency or absence of endogenous testosterone.

1. Primary hypogonadism (congenital or acquired)-testicular failure due to cryptorchidism, bilateral torsion, orchitis, vanishing testis syndrome; or orchidectomy.

2. Hypogonadotropic hypogonadism (congenital or acquired)-idiopathic gonadotropin or LHRH deficiency, or pituitary-hypothalamic injury from tumors, trauma, or radiation.


See all Depo-Testosterone indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Depo-Testosterone (Testosterone)

Man With Micropenis Responds to Testosterone
Source: MedPageToday.com - medical news plus CME for physicians [2016.05.27]
(MedPage Today) -- Therapy helps Kallmann syndrome patient

Prostate cancer: Testosterone therapy 'does not increase aggressive disease risk'
Source: Prostate / Prostate Cancer News From Medical News Today [2016.05.09]
A study using Swedish data finds men prescribed testosterone for over a year had no overall rise in prostate cancer risk, and they showed a 50 percent fall in aggressive disease.

Studies show oral testosterone safe and efficacious in long-term management of hypogonadism
Source: Endocrinology News From Medical News Today [2016.05.08]
Research highlights safety and efficacy of novel treatment option for hypogonadism over 52-week periodLCPN10, a novel oral testosterone undecanoate formulation has been shown to be safe and...

Studies demonstrate protective effects of testosterone in hypogonadal men
Source: Endocrinology News From Medical News Today [2016.05.07]
Maintaining healthy levels of testosterone (T) may decrease a man's risk of developing not only prostate cancer, but also other metabolic conditions, according to new research being presented at the...

Testosterone undecanoate improves sexual function in men with type 2 diabetes and very low testosterone
Source: Endocrinology News From Medical News Today [2016.05.06]
In a recent placebo-controlled study, long acting testosterone undecanoate (an ester of testosterone) improved erectile function, intercourse satisfaction, and sexual desire scores in type 2...

more news >>

Published Studies Related to Depo-Testosterone (Testosterone)

Testosterone replacement therapy in older male subjective memory complainers: double-blind randomized crossover placebo-controlled clinical trial of physiological assessment and safety. [2015]
Testosterone replacement therapy (TRT) has been investigated in older men as a preventative treatment against Alzheimer's disease and dementia. However, previous studies have been contradictory... Our study suggests TRT is safe and well-tolerated in this Indonesian cohort, yet longitudinal studies with larger cohorts are needed to assess TRT further, and to establish whether TRT reduces dementia risk.

Testosterone induces erythrocytosis via increased erythropoietin and suppressed hepcidin: evidence for a new erythropoietin/hemoglobin set point. [2014]
hematocrit remain unclear... CONCLUSIONS: Testosterone-induced increase in hemoglobin and hematocrit is

Effect of testosterone treatment on constitutional and sexual symptoms in men with type 2 diabetes in a randomized, placebo-controlled clinical trial. [2014]
constitutional and sexual symptoms in men with type 2 diabetes (T2D)... CONCLUSIONS: In this trial, T treatment did not substantially improve

The role of androgen receptor CAG repeat polymorphism and other factors which affect the clinical response to testosterone replacement in metabolic syndrome and type 2 diabetes: TIMES2 sub-study. [2013]
TRT in the TIMES2 study... CONCLUSION: AR CAG affected the response of some variables to TRT in the TIMES2

Mechanical muscle function and lean body mass during supervised strength training and testosterone therapy in aging men with low-normal testosterone levels. [2013]
24-week study... CONCLUSION: Strength training in aging men with low-normal testosterone levels

more studies >>

Clinical Trials Related to Depo-Testosterone (Testosterone)

Effect of Androgel on Type 2 Diabetic Males With Hypogonadism [Active, not recruiting]
This is to study the effect of replacing testosterone on different inflammatory cells in type 2 diabetics with low testosterone levels.

Safety Study of Transdermal Testosterone for Low Libido in Pre and Postmenopausal Women [Completed]
Female sexual dysfunction (FSD) is an established side effect of Selective serotonin reuptake inhibitors (SSRIs) and serotonin noradrenalin reuptake inhibitors (SNRIs), causing symptoms such as loss of libido, arousal difficulties, or delayed orgasm or anorgasmia. Efficacy of testosterone therapy for the treatment of hypoactive sexual desire disorder (HSDD) in women has been demonstrated in studies including naturally and surgically menopausal women, either alone or in combination with estrogen, with or without progestin therapy.

TRADE-Testosterone Replacement and Dutasteride Effectiveness [Completed]
The purpose of this research study is to determine whether the combination of the male hormone testosterone [T] in gel form and the oral drug dutasteride [D], used to shrink large prostate glands can safely reduce the size of the prostate gland and symptoms of prostate enlargement (called benign prostatic hyperplasia [BPH]) compared to T treatment alone in men with low testosterone (called hypogonadism).

Pharmacokinetic Study of Testosterone Enanthate [Completed]

Anabolic and Inflammatory Responses to Short-Term Testosterone Administration in Older Men [Recruiting]
Skeletal muscle loss is a common consequence of aging and in some individuals reaches a level that compromises health and quality of life. Age-associated increases in cytokine and inflammatory signaling may be important contributors to this process. In this project the investigators will test the hypotheses that 1) testosterone will inhibit cytokine and inflammatory signaling in skeletal muscles of older adults and 2) will augment the anabolic response to increased skeletal muscle activity. The investigators will also assess the practical question of whether testosterone injection and gel application elicit similar responses. Resistance exercise will be used as a means of stimulating both inflammatory and anabolic responses in skeletal muscle. In order to assess the effects of testosterone on these responses, fourteen subjects will perform resistance exercise on two occasions separated by 7 days. The first session will be performed prior to the initiation of testosterone therapy and the second session will be performed after receiving testosterone for 7 days.

more trials >>

Reports of Suspected Depo-Testosterone (Testosterone) Side Effects

Poor Quality Drug Administered (33)Burning Sensation (30)Drug Ineffective (11)Feeling Hot (8)Injection Site Pain (7)Malaise (6)Rash (5)Pain (4)Headache (4)Injection Site Swelling (4)more >>


Page last updated: 2016-05-27

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