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Depo-Provera (Medroxyprogesterone Acetate) - Summary

 

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DEPO-PROVERA SUMMARY

DEPO-PROVERA Contraceptive Injection contains medroxyprogesterone acetate, a derivative of progesterone, as its active ingredient. Medroxyprogesterone acetate is active by the parenteral and oral routes of administration.

DEPO-PROVERA Contraceptive Injection is indicated only for the prevention of pregnancy. To ensure that DEPO-PROVERA Contraceptive Injection is not administered inadvertently to a pregnant woman, the first injection must be given ONLY during the first 5 days of a normal menstrual period; ONLY within the first 5-days postpartum if not breast-feeding, and if exclusively breast-feeding, ONLY at the sixth postpartum week. The efficacy of DEPO-PROVERA Contraceptive Injection depends on adherence to the recommended dosage schedule (see DOSAGE AND ADMINISTRATION). It is a long-term injectable contraceptive in women when administered at 3-month (13-week) intervals. Dosage does not need to be adjusted for body weight.

DEPO-PROVERA NEWS HIGHLIGHTS

Media Articles Related to Depo-Provera (Medroxyprogesterone)

Bone Mineral Density Concerns Should Not Discourage Use Of Contraceptive Shot
Source: Pregnancy / Obstetrics News From Medical News Today [2008.09.02]

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Published Studies Related to Depo-Provera (Medroxyprogesterone)

Estrogen, medroxyprogesterone acetate, endothelial function, and biomarkers of cardiovascular risk in young women. [2008.04]

Association between caffeine intake and bone mass among young women: potential effect modification by depot medroxyprogesterone acetate use. [2008.04]

Continuous oral or intramuscular medroxyprogesterone acetate versus the levonorgestrel releasing intrauterine system in the treatment of perimenopausal menorrhagia: a randomized, prospective, controlled clinical trial in female smokers. [2008]

A comparative study of Cyclofem and depot medroxyprogesterone acetate (DMPA) effects on endometrial vasculature. [2007.10]

Body composition during treatment with conjugated estrogens with and without medroxyprogesterone acetate: analysis of the women's Health, Osteoporosis, Progestin, Estrogen (HOPE) trial. [2007.08]

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Clinical Trials Related to Depo-Provera (Medroxyprogesterone)

Depo-Medroxyprogesterone Acetate (DMPA, Depo-Provera) Use With Certain Anti-HIV Drugs in HIV-Infected Women [Completed]

Depo-Provera: Bone Mineral Density and Total Body Calcium in Adolescent DP150CI Users and Non-Hormonal Contraception [Completed]

Pilot Study of Femring Estrogen Supplementation During Depo-Provera Initiation [Recruiting]

Surgery Plus Medroxyprogesterone in Preventing Endometrial Cancer [Active, not recruiting]

Medroxyprogesterone or Interferon and/or Aldesleukin in Treating Patients With Metastatic Kidney Cancer [Active, not recruiting]

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Page last updated: 2008-09-02

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