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Depakote (Divalproex Sodium) - Published Studies

 



Depakote Related Published Studies

Well-designed clinical trials related to Depakote (Divalproex)

Olanzapine-Divalproex combination versus divalproex monotherapy in the treatment of bipolar mixed episodes: a double-blind, placebo-controlled study. [2009.09.22]

A double-blind, randomized, placebo-controlled trial of divalproex extended-release in the treatment of bipolar disorder in children and adolescents. [2009.05]

A preliminary controlled trial of divalproex in posttraumatic stress disorder. [2009.04]

Comparative efficacy and safety of oxcarbazepine versus divalproex sodium in the treatment of acute mania: a pilot study. [2009.04]

Maintenance treatment for patients with bipolar I disorder: results from a north american study of quetiapine in combination with lithium or divalproex (trial 127). [2009.04]

Divalproex ER combined with olanzapine or risperidone for treatment of acute exacerbations of schizophrenia. [2009.04]

A 6-month, double-blind, maintenance trial of lithium monotherapy versus the combination of lithium and divalproex for rapid-cycling bipolar disorder and Co-occurring substance abuse or dependence. [2009.01]

Divalproex sodium extended-release for the prophylaxis of migraine headache in adolescents: results of a stand-alone, long-term open-label safety study. [2009.01]

Olanzapine versus divalproex versus placebo in the treatment of mild to moderate mania: a randomized, 12-week, double-blind study. [2008.11]

Divalproex in the treatment of posttraumatic stress disorder: a randomized, double-blind, placebo-controlled trial in a veteran population. [2008.02]

Divalproex in the treatment of acute bipolar depression: a preliminary double-blind, randomized, placebo-controlled pilot study. [2007.12]

Divalproex Sodium for the Treatment of PTSD and Conduct Disordered Youth: A Pilot Randomized Controlled Clinical Trial. [2007.10]

A double blind, randomized, placebo-controlled trial of quetiapine as an add-on therapy to lithium or divalproex for the treatment of bipolar mania. [2007.07]

Double-blind, placebo-controlled trial of divalproex monotherapy in the treatment of symptomatic youth at high risk for developing bipolar disorder. [2007.05]

Efficacy profiles of psychopharmacology: divalproex sodium in conduct disorder. [2006.09]

Reduced suicidal ideation in bipolar I disorder mixed-episode patients in a placebo-controlled trial of olanzapine combined with lithium or divalproex. [2006.08]

Comparative absorption profiles of divalproex sodium delayed-release versus extended-release tablets -- clinical implications. [2006.04]

Divalproex sodium vs. placebo in the treatment of repetitive behaviours in autism spectrum disorder. [2006.04]

A double-blind randomized pilot study comparing quetiapine and divalproex for adolescent mania. [2006.03]

Every-12-hour administration of extended-release divalproex in patients with epilepsy: impact on plasma valproic acid concentrations. [2006.03]

A randomized, double-blind, placebo-controlled pilot trial of safety and tolerability of two doses of divalproex sodium in outpatients with probable Alzheimer's disease. [2005.12]

Baseline predictors of response to divalproex in conduct disorder. [2005.12]

A 20-month, double-blind, maintenance trial of lithium versus divalproex in rapid-cycling bipolar disorder. [2005.11]

Divalproex sodium in nursing home residents with possible or probable Alzheimer Disease complicated by agitation: a randomized, controlled trial. [2005.11]

Relationship of mania symptomatology to maintenance treatment response with divalproex, lithium, or placebo. [2005.10]

Effect of divalproex on metabolic parameters is dose related in migraine prophylaxis. [2005.09]

Once-a-day extended-release dosage form of divalproex sodium III: development and validation of a Level A in vitro-in vivo correlation (IVIVC). [2005.09]

Effectiveness and medical costs of divalproex versus lithium in the treatment of bipolar disorder: results of a naturalistic clinical trial. [2005.06]

Divalproex sodium for pediatric mixed mania: a 6-month prospective trial. [2005.06]

Double-blind 18-month trial of lithium versus divalproex maintenance treatment in pediatric bipolar disorder. [2005.05]

Service utilization and costs of olanzapine versus divalproex treatment for acute mania: results from a randomized, 47-week clinical trial. [2005.04]

Divalproex in the treatment of bipolar depression: a placebo-controlled study. [2005.04]

Impact of trait impulsivity and state aggression on divalproex versus placebo response in borderline personality disorder. [2005.03]

Extended-release divalproex in child and adolescent outpatients with epilepsy. [2005.03]

Lower effectiveness of divalproex versus valproic acid in a prospective, quasi-experimental clinical trial involving 9,260 psychiatric admissions. [2005.02]

Divalproex sodium in the management of post-herpetic neuralgia: a randomized double-blind placebo-controlled study. [2005.01]

Randomized, placebo-controlled trial of mixed amphetamine salts for symptoms of comorbid ADHD in pediatric bipolar disorder after mood stabilization with divalproex sodium. [2005.01]

Topiramate and divalproex in combination with risperidone for acute mania: a randomized open-label study. [2005.01]

Quetiapine versus placebo in combination with lithium or divalproex for the treatment of bipolar mania. [2004.12]

Pharmacokinetics and safety of extended-release divalproex sodium tablets: morning versus evening administration. [2004.11.01]

Comparison of the bioavailability of 250 and 500 mg divalproex sodium extended-release tablets in healthy volunteers. [2004.11]

Quetiapine with lithium or divalproex for the treatment of bipolar mania: a randomized, double-blind, placebo-controlled study. [2004.06]

Adjunctive divalproex and hostility among patients with schizophrenia receiving olanzapine or risperidone. [2004.03]

Pharmacotherapy for marijuana dependence: a double-blind, placebo-controlled pilot study of divalproex sodium. [2004.01]

Risperidone does not affect steady-state pharmacokinetics of divalproex sodium in patients with bipolar disorder. [2004]

Divalproex sodium for the treatment of conduct disorder: a randomized controlled clinical trial. [2003.10]

Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: a 47-week study. [2003.07]

Maintenance efficacy of divalproex in the prevention of bipolar depression. [2003.07]

Once-a-day controlled-release dosage form of divalproex sodium I: formulation design and in vitro/in vivo investigations. [2003.06]

Divalproex in the treatment of impulsive aggression: efficacy in cluster B personality disorders. [2003.06]

Divalproex sodium versus olanzapine in the treatment of acute mania in bipolar disorder: health-related quality of life and medical cost outcomes. [2003.03]

Effect of divalproex combined with olanzapine or risperidone in patients with an acute exacerbation of schizophrenia. [2003.01]

A comparison of the efficacy, safety, and tolerability of divalproex sodium and olanzapine in the treatment of bipolar disorder. [2002.12]

The use of divalproex in alcohol relapse prevention: a pilot study. [2002.08.01]

Divalproex extended-release versus the original divalproex tablet: results of a randomized, crossover study of well-controlled epileptic patients with primary generalized seizures. [2002.08]

A randomized trial of divalproex sodium extended-release tablets in migraine prophylaxis. [2002.06.11]

Olanzapine versus divalproex in the treatment of acute mania. [2002.06]

Divalproex sodium treatment of women with borderline personality disorder and bipolar II disorder: a double-blind placebo-controlled pilot study. [2002.05]

Pattern of response to divalproex, lithium, or placebo in four naturalistic subtypes of mania. [2002.04]

Comparison of the bioavailability of unequal doses of divalproex sodium extended-release formulation relative to the delayed-release formulation in healthy volunteers. [2002.03]

Divalproex sodium (Depakote) for alcohol withdrawal and relapse prevention. [2002]

Divalproex therapy in medication-naive and mood-stabilizer-naive bipolar II depression. [2001.12]

Divalproex sodium in alcohol withdrawal: a randomized double-blind placebo-controlled clinical trial. [2001.09]

[Prediction of treatment response in acute mania: controlled clinical trials with divalproex] [2001.05]

A preliminary double-blind, placebo-controlled trial of divalproex sodium in borderline personality disorder. [2001.03]

Placebo-controlled study of divalproex sodium for agitation in dementia. [2001.01]

Effects of divalproex versus lithium on length of hospital stay among patients with bipolar disorder. [2000.09]

Effect size of lithium, divalproex sodium, and carbamazepine in children and adolescents with bipolar disorder. [2000.06]

Randomized, placebo-controlled pilot study of divalproex sodium in the treatment of acute exacerbations of chronic schizophrenia. [2000.06]

A randomized, placebo-controlled 12-month trial of divalproex and lithium in treatment of outpatients with bipolar I disorder. Divalproex Maintenance Study Group. [2000.05]

Divalproex treatment for youth with explosive temper and mood lability: a double-blind, placebo-controlled crossover design. [2000.05]

Safety and tolerability of oral loading divalproex sodium in acutely manic bipolar patients. [1999.12]

Differential effect of number of previous episodes of affective disorder on response to lithium or divalproex in acute mania. [1999.08]

A comparison of divalproex with propranolol and placebo for the prophylaxis of migraine without aura. [1997.09]

Divalproex sodium in migraine prophylaxis: a dose-controlled study. [1997.04]

A pilot study of lithium carbonate plus divalproex sodium for the continuation and maintenance treatment of patients with bipolar I disorder. [1997.03]

Safety and efficacy of divalproex sodium monotherapy in partial epilepsy: a double-blind, concentration-response design clinical trial. Depakote Monotherapy for Partial Seizures Study Group. [1997.01]

Depression during mania. Treatment response to lithium or divalproex. [1997.01]

Maintenance clinical trials in bipolar disorder: design implications of the divalproex-lithium-placebo study. [1997]

Effect size of efficacy measures comparing divalproex, lithium and placebo in acute mania. [1997]

Pharmacokinetic interactions and side effects resulting from concomitant administration of lithium and divalproex sodium. [1996.05]

A randomized, blinded, placebo-controlled trial of divalproex sodium prophylaxis in adults with newly diagnosed brain tumors. [1996.04]

A randomized comparison of divalproex oral loading versus haloperidol in the initial treatment of acute psychotic mania. [1996.04]

Plasma GABA predicts acute response to divalproex in mania. [1996.02.15]

Efficacy and safety of add-on divalproex sodium in the treatment of complex partial seizures. The M88-194 Study Group. [1996.01]

Migraine prophylaxis with divalproex. [1995.03]

Efficacy of divalproex vs lithium and placebo in the treatment of mania. The Depakote Mania Study Group. [1994.03.23]

Well-designed clinical trials possibly related to Depakote (Divalproex)

Anticonvulsant drugs for pediatric migraine prevention: an evidence-based review. [2009.10]

Effect of valproic acid on body weight, food intake, physical activity and hormones: results of a randomized controlled trial. [2009.09]

Randomized sequential trial of valproic acid in amyotrophic lateral sclerosis. [2009.08]

Effects of valproic acid on sleep in children with epilepsy. [2009.08]

Valproate preparations for agitation in dementia. [2009.07.08]

Valproate treatment and cocaine cue reactivity in cocaine dependent individuals. [2009.06.01]

A double-blind randomized trial of mood stabilizer augmentation using lamotrigine and valproate for patients with schizophrenia who are stabilized and partially responsive. [2009.06]

Lamotrigine and valproate pharmacokinetics interactions in epileptic patients. [2009.04]

Effects of valproate or lamotrigine monotherapy on the reproductive endocrine and insulin-related metabolic profile in Chinese adults with epilepsy: a prospective randomized study. [2009.04]

Lamotrigine and valproic acid have different effects on motorcortical neuronal excitability. [2009.04]

A limited number of 5-azacitidine cycles can be effective treatment in MDS. [2009.03]

Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures: a randomized, double-blind, placebo-controlled, parallel-group phase III study. [2009.03]

Management of diabetic neuropathy by sodium valproate and glyceryl trinitrate spray: a prospective double-blind randomized placebo-controlled study. [2009.03]

Comparison of add-on valproate and primidone in carbamazepine-unresponsive patients with partial epilepsy. [2009.03]

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