Depacon Related Published Studies
Well-designed clinical trials related to Depacon (Valproate)
Valproate preparations for agitation in dementia. [2009.07.08]
Valproate treatment and cocaine cue reactivity in cocaine dependent individuals. [2009.06.01]
A double-blind randomized trial of mood stabilizer augmentation using lamotrigine and valproate for patients with schizophrenia who are stabilized and partially responsive. [2009.06]
Lamotrigine and valproate pharmacokinetics interactions in epileptic patients. [2009.04]
Effects of valproate or lamotrigine monotherapy on the reproductive endocrine and insulin-related metabolic profile in Chinese adults with epilepsy: a prospective randomized study. [2009.04]
Folic acid efficacy as an alternative drug added to sodium valproate in the treatment of acute phase of mania in bipolar disorder: a double-blind randomized controlled trial. [2009.03.10]
Management of diabetic neuropathy by sodium valproate and glyceryl trinitrate spray: a prospective double-blind randomized placebo-controlled study. [2009.03]
Comparison of add-on valproate and primidone in carbamazepine-unresponsive patients with partial epilepsy. [2009.03]
Comparison of the effectiveness of topiramate and sodium valproate in pediatric migraine. [2008.12]
Efficacy of adjunctive aripiprazole to either valproate or lithium in bipolar mania patients partially nonresponsive to valproate/lithium monotherapy: a placebo-controlled study. [2008.10]
A 12-week, open, randomized trial comparing sodium valproate to lithium in patients with bipolar I disorder suffering from a manic episode. [2008.09]
Hyperandrogenism, ovulatory dysfunction, and polycystic ovary syndrome with valproate versus lamotrigine. [2008.08]
Cinnarizine in refractory migraine prophylaxis: efficacy and tolerability. A comparison with sodium valproate. [2008.04]
Valproate-induced thrombocytopenia: a prospective monotherapy study. [2008.03]
Valproate (depakine-chrono) in the acute treatment of outpatients with generalized anxiety disorder without psychiatric comorbidity: randomized, double-blind placebo-controlled study. [2008.03]
The effect of sodium valproate on chronic daily headache and its subgroups. [2008.02]
The cognitive effects of oxcarbazepine versus carbamazepine or valproate in newly diagnosed children with partial seizures. [2007.12]
Intravenous sodium valproate versus diazepam infusion for the control of refractory status epilepticus in children: a randomized controlled trial. [2007.10]
Subcutaneous histamine versus sodium valproate in migraine prophylaxis: a randomized, controlled, double-blind study. [2007.10]
Topiramate or valproate in patients with juvenile myoclonic epilepsy: A randomized open-label comparison. [2007.06]
The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial. [2007.03.24]
Safety of rapid intravenous valproate infusion in pediatric patients. [2007.02]
A placebo-controlled trial of valproate for agitation and aggression in Alzheimer's disease. [2007]
Efficacy of carbamazepine and valproate as monotherapy for early epilepsy and single seizures. [2006.11.28]
Sodium valproate vs phenytoin in status epilepticus: a pilot study. [2006.07.25]
Inositol augmentation of lithium or valproate for bipolar depression. [2006.04]
Modulation of serum concentrations of melatonin by carbamazepine and valproate. [2006.01]
Valproate attenuates dextroamphetamine-induced subjective changes more than lithium. [2005.12]
Efficacy of topiramate and valproate in chronic migraine. [2005.11]
A double-blind, placebo-controlled study of valproate for aggression in youth with pervasive developmental disorders. [2005.08]
Differential effects of chronic lithium and valproate on brain activation in healthy volunteers. [2005.08]
A placebo-controlled screening trial of olanzapine, valproate, and coenzyme Q10/L-carnitine for the treatment of cocaine dependence. [2005.03]
Lithium and valproate attenuate dextroamphetamine-induced changes in brain activation. [2005.03]
Bioequivalence of a new sustained-release formulation of sodium valproate, valproate modified-release granules, compared with existing sustained-release formulations after once- or twice-daily administration. [2005.01]
Comparison of intravenous valproate with intravenous lysine-acetylsalicylic acid in acute migraine attacks. [2005.01]
Efficacy of valproate maintenance in patients with bipolar disorder and alcoholism: a double-blind placebo-controlled study. [2005.01]
Efficacy of olanzapine combined with valproate or lithium in the treatment of dysphoric mania. [2004.12]
A randomized, double-blind, placebo controlled trial of melatonin add-on therapy in epileptic children on valproate monotherapy: effect on glutathione peroxidase and glutathione reductase enzymes. [2004.11]
Efficacy and tolerability of conversion to monotherapy with lamotrigine compared with valproate and carbamazepine in patients with epilepsy. [2004.08]
The prophylactic effect of valproate on glyceryltrinitrate induced migraine. [2004.07]
Add-on melatonin improves quality of life in epileptic children on valproate monotherapy: a randomized, double-blind, placebo-controlled trial. [2004.06]
The effectiveness of divalproate in all forms of mania and the broader bipolar spectrum: many questions, few answers. [2004.04]
Topiramate, carbamazepine, and valproate monotherapy: double-blind comparison in children with newly diagnosed epilepsy. [2004.02]
Sodium valproate for painful diabetic neuropathy: a randomized double-blind placebo-controlled study. [2004.01]
Effect of valproate on hemostatic function in patients with traumatic brain injury. [2003.12]
Lamotrigine monotherapy compared with carbamazepine, phenytoin, or valproate monotherapy in patients with epilepsy. [2003.12]
Valproate therapy for agitation in dementia: open-label extension of a double-blind trial. [2003.07]
Intravenous sodium valproate versus prochlorperazine for the emergency department treatment of acute migraine headaches: a prospective, randomized, double-blind trial. [2003.06]
Differential cognitive and behavioral effects of topiramate and valproate. [2003.05.13]
Topiramate, carbamazepine and valproate monotherapy: double-blind comparison in newly diagnosed epilepsy. [2003.03]
Lamotrigine versus valproate monotherapy-associated weight change in adolescents with epilepsy: results from a post hoc analysis of a randomized, double-blind clinical trial. [2003.02]
Safety and tolerance of rapidly infused Depacon. A randomized trial in subjects with epilepsy. [2003.01]
Sodium valproate in the management of painful neuropathy in type 2 diabetes - a randomized placebo controlled study. [2002.11]
A pilot study of loading versus titration of valproate in the treatment of acute mania. [2002.10]
Lithium and valproate treatment of pathological gambling: a randomized single-blind study. [2002.07]
Sodium valproate in the treatment of aggressive behavior in patients with dementia--a randomized placebo controlled clinical trial. [2002.06]
Randomized double-blind parallel-group study comparing cognitive effects of a low-dose lamotrigine with valproate and placebo in healthy volunteers. [2002.01]
Efficacy of olanzapine in combination with valproate or lithium in the treatment of mania in patients partially nonresponsive to valproate or lithium monotherapy. [2002.01]
Comparison of intravenous valproate versus intramuscular dihydroergotamine and metoclopramide for acute treatment of migraine headache. [2001.11]
Weight change associated with valproate and lamotrigine monotherapy in patients with epilepsy. [2001.01.23]
Phenytoin versus valproate monotherapy for partial onset seizures and generalized onset tonic-clonic seizures. [2001]
[Effectiveness, safety and practicality of delayed-release minitablets of valproate in bipolar affective disorders] [2000.11]
Can sodium valproate improve learning in children with epileptiform bursts but without clinical seizures? [2000.11]
A multicenter, randomized clinical study to evaluate the effect on cognitive function of topiramate compared with valproate as add-on therapy to carbamazepine in patients with partial-onset seizures. [2000.09]
Study on the dose proportionality of the pharmacokinetics of sustained release sodium valproate. [2000.08]
Weight gain associated with valproate in childhood. [2000.05]
Valproate as an adjunct to neuroleptic medication for the treatment of acute episodes of mania: a prospective, randomized, double-blind, placebo-controlled, multicenter study. European Valproate Mania Study Group. [2000.04]
Neuropsychological effects of valproate in traumatic brain injury: a randomized trial. [2000.02.22]
Carbamazepine versus valproate monotherapy for epilepsy. [2000]
Valproate therapy for prevention of posttraumatic seizures: a randomized trial. [1999.10]
Comparative double blind clinical trial of phenytoin and sodium valproate as anticonvulsant prophylaxis after craniotomy: efficacy, tolerability, and cognitive effects. [1999.10]
Effects of carbamazepine and valproate on haloperidol plasma levels and on psychopathologic outcome in schizophrenic patients. [1999.08]
Double-blind substitution of vigabatrin and valproate in carbamazepine-resistant partial epilepsy. 012 Study group. [1999.04]
Valproate monotherapy in juvenile myoclonic epilepsy: dose-related effects on electroencephalographic and other neurophysiologic tests. [1999.02]
Trazodone and valproate in patients discontinuing long-term benzodiazepine therapy: effects on withdrawal symptoms and taper outcome. [1999.01]
Combined treatment of schizophrenic psychoses with haloperidol and valproate. [1998.07]
A pilot open randomized trial of valproate and phenobarbital in the treatment of acute alcohol withdrawal. [1998.06]
Prophylactic sodium valproate therapy in patients with drug-resistant migraine. [1998.05]
Valproate as monotherapy for juvenile myoclonic epilepsy: dose-effect study. [1998.04]
Influence of food on the pharmacokinetics of a new multiple unit sustained release sodium valproate formulation. [1997.12]
Valproate prophylaxis in a prospective clinical trial of refractory bipolar disorder. [1997.10]
Valproate versus flunarizine in migraine prophylaxis: a randomized, double-open, clinical trial. [1997.09]
An open trial of valproate for agitation in geriatric neuropsychiatric disorders. [1997.09]
Lack of pharmacokinetic interaction between remacemide hydrochloride and sodium valproate in epileptic patients. [1997.06]
Effect of valproate on the pharmacokinetics and pharmacodynamics of lorazepam. [1997.05]
Weight gain with valproate or carbamazepine--a reappraisal. [1997.04]
A double-blind controlled clinical trial: oxcarbazepine versus sodium valproate in adults with newly diagnosed epilepsy. [1997.03]
Suppression of nocturnal plasma melatonin levels by evening administration of sodium valproate in healthy humans. [1997.02.01]
The effect of repeated-dose activated charcoal on the pharmacokinetics of sodium valproate in healthy volunteers. [1997.01]
A pharmacokinetic study to determine the drug interaction between valproate and propranolol. [1996.11]
Effect of valproate on cognitive functioning. Comparison with carbamazepine. The Department of Veterans Affairs Epilepsy Cooperative Study 264 Group. [1996.10]
Bidirectional interaction of valproate and lamotrigine in healthy subjects. [1996.08]
Comparison of phenobarbitone, phenytoin with sodium valproate: randomized, double-blind study. [1996.07]
Relation of serum valproate concentration to response in mania. [1996.06]
[Open randomized comparative trial of sodium valproate and carbamazepine in adult onset epilepsy] [1996.05]
Randomised comparative monotherapy trial of phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed childhood epilepsy. [1996.03.16]
Epilim chrono: a multidose, crossover comparison of two formulations of valproate in healthy volunteers. [1996.03]
Valproate as an antidepressant in major depressive disorder. [1996]
Carbamazepine but not valproate induces bupropion metabolism. [1995.10]
Comparative cognitive effects of phenobarbital, phenytoin, and valproate in healthy adults. [1995.08]
Effect of sodium valproate on naloxone-stimulated ACTH and cortisol release in humans. [1995.06]
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