Demadex (Torsemide) - Summary

DEMADEX SUMMARY

DEMADEX^® 
(torsemide)
 TABLETS
 INJECTION

DEMADEX (torsemide) is a diuretic of the pyridine-sulfonylurea class.

DEMADEX is indicated for the treatment of edema associated with congestive heart failure, renal disease, or hepatic disease. Use of torsemide has been found to be effective for the treatment of edema associated with chronic renal failure. Chronic use of any diuretic in hepatic disease has not been studied in adequate and well-controlled trials.

DEMADEX intravenous injection is indicated when a rapid onset of diuresis is desired or when oral administration is impractical.

DEMADEX is indicated for the treatment of hypertension alone or in combination with other antihypertensive agents.

DEMADEX NEWS HIGHLIGHTS

Published Studies Related to Demadex (Torsemide)

Torsemide versus furosemide after continuous renal replacement therapy due to acute renal failure in cardiac surgery patients. [2005]

Open-label randomized trial of torsemide compared with furosemide therapy for patients with heart failure. [2001.11]

Long-term efficacy of torsemide compared with frusemide in cirrhotic patients with ascites. [2001.03]

Pharmacodynamics of torsemide administered as an intravenous injection and as a continuous infusion to patients with congestive heart failure. [1996.03]

Bioavailability, pharmacokinetics, and pharmacodynamics of torsemide and furosemide in patients with congestive heart failure. [1995.06]

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Clinical Trials Related to Demadex (Torsemide)

Bioavailability Study of Torsemide Tablets Under Fed Conditions [Completed]

Bioavailability Study of Torsemide Tablets Under Fasting Conditions [Completed]

Hypertension Study: Multinational Torasemide Trial in Mild to Moderate Hypertension. [Completed]

Effect of a New Formulation of Torasemide (Prolonged Release)on Myocardial Fibrosis in Patients With Heart Failure. [Recruiting]

Bioequivalency Study of Torsemide Tablets Under Fasting Conditions [Completed]

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