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Deltasone (Prednisone) - Side Effects and Adverse Reactions



Fluid and Electrolyte Disturbances: Sodium retention, fluid retention, congestive heart failure in susceptible patients, potassium loss, hypokalemic alkalosis, and hypertension.

Musculoskeletal: Muscle weakness, steriod myopathy, loss of muscle mass, osteoporosis, tendon rupture, particularly of the Achilles tendon, vertebral compression fractures, aseptic necrosis of femoral and humeral heads, and pathologic fracture of long bones.

Gastrointestinal: Peptic ulcer with possible perforation and hemorrhage; pancreatitis; abdominal distention; ulcerative esophagitis; Increases in alanine transaminase (ALT, SGPT), aspartate transaminase (AST, SGOT) and alkaline phosphatase have been observed following corticosteroid treatment. These changes are usually small, not associated with any clinical syndrome and are reversible upon discontinuation.

Dermatologic: Impaired wound healing, thin fragile skin, petechiae and ecchymoses, facial erythema, increased sweating, and may suppress reactions to skin tests.

Metabolic: Negative nitrogen balance due to protein catabolism.

Neurological: Increased intracranial pressure with papilledema (pseudo-tumor cerebri) usually after treatment, convulsions, vertigo, and headache.

Endocrine: Menstrual irregularities; development of Cushingoid state; secondary adrenocortical and pituitary unresponsiveness, particularly in times of stress, as in trauma, surgery or illness; suppression of growth of children; decreased carbohydrate tolerance; manifestations of latent diabetes mellitus; increased requirements for insulin or oral hypoglycemic agents in diabetics.

Ophthalmic: Posterior subcapsular cataracts, increased intraocular pressure, glaucoma, and exophthalmos.

Additional Reactions: Urticaria and other allergic, anaphylactic or hypersensitivity reactions.


Below is a sample of reports where side effects / adverse reactions may be related to Deltasone. The information is not vetted and should not be considered as verified clinical evidence.

Possible Deltasone side effects / adverse reactions in 42 year old male

Reported by a health professional (non-physician/pharmacist) from Argentina on 2011-11-22

Patient: 42 year old male

Reactions: Pulmonary Tuberculosis

Adverse event resulted in: hospitalization

Suspect drug(s):
    Dosage: route=ev
    Indication: Renal Transplant
    Start date: 2006-06-05

Mycophenolate Mofetil (Cellcept)
    Indication: Renal Transplant
    Start date: 2006-06-05

    Dosage: started on 05jan2011
    Indication: Renal Transplant
    Start date: 2006-06-05

Possible Deltasone side effects / adverse reactions in 23 year old male

Reported by a physician from United States on 2012-08-15

Patient: 23 year old male weighing 60.0 kg (132.0 pounds)

Reactions: Pneumonia

Adverse event resulted in: hospitalization

Suspect drug(s):
    Dosage: strength:5mg; 4 tablets daily
    Administration route: Oral
    Indication: Crohn's Disease
    Start date: 2010-11-12

    Indication: Crohn's Disease
    Start date: 2010-12-26

Other drugs received by patient: Vitamin B-12; Lactinex; Ultram; Boost Plus; Vitamin B-12; Folic Acid; Vitamin B-12; Prilosec; Multi MAX PO; Methotrexate; Calcium Carbonate-Vitamin D; Vitamin B-12

See index of all Deltasone side effect reports >>

Drug label data at the top of this Page last updated: 2006-09-17

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