DESCRIPTION
DDAVP® Nasal Spray (desmopressin acetate) is a synthetic analogue of the natural pituitary hormone 8-arginine vasopressin (ADH), an antidiuretic hormone affecting renal water conservation. It is chemically defined as follows:
Mol. wt. 1183.34
Empirical formula: C46H64N14O12S2·C2H4O2·3H2O
1-(3-mercaptopropionic acid)-8-D-arginine vasopressin monoacetate (salt) trihydrate. DDAVP Nasal Spray is provided as an aqueous solution for intranasal use.
Each mL contains:
Desmopressin acetate......................................... 0.1 mg
Sodium Chloride............................................... 7.5 mg
Citric acid monohydrate..................................... 1.7 mg
Disodium phosphate dihydrate............................. 3.0 mg
Benzalkonium chloride solution (50%).................. 0.2 mg
The DDAVP Nasal Spray compression pump delivers 0.1 mL (10 µg) of DDAVP (desmopressin acetate) per spray.
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