Darvon (Propoxyphene Hydrochloride) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

In a survey conducted in hospitalized patients, less than 1% of patients taking propoxyphene hydrochloride at recommended doses experienced side effects. The most frequently reported were dizziness, sedation, nausea, and vomiting. Some of these adverse reactions may be alleviated if the patient lies down.

Other adverse reactions include constipation, abdominal pain, skin rashes, lightheadedness, headache, weakness, euphoria, dysphoria, hallucinations, and minor visual disturbances.

Propoxyphene therapy has been associated with abnormal liver function tests and, more rarely, with instances of reversible jaundice (including cholestatic jaundice).

Subacute painful myopathy has occurred following chronic propoxyphene overdosage.

REPORTS OF SIDE EFFECTS / ADVERSE REACTIONS RELATED TO DARVON

Possible Darvon side effects / adverse reactions in 42 year old male

Reported by a individual with unspecified qualification from United States on 2009-06-15

Patient: 42 year old male weighing 91.2 kg (200.6 pounds)

Reactions: Confusional State, Anxiety, Hallucinations, Mixed, Incorrect Dose Administered, Drug Interaction, Mental Disorder, Somnambulism, Delirium

Suspect drug(s):
Clonidine
    Dosage: .2mg
    Indication: Back Pain
    Start date: 2001-05-19
    End date: 2002-05-19

Clonidine
    Dosage: .2mg
    Indication: Hypertension
    Start date: 2001-05-19
    End date: 2002-05-19

Darvon
    Dosage: 195 mg
    Indication: Back Pain
    Start date: 2001-05-19
    End date: 2002-05-19

Darvon
    Dosage: 195 mg
    Indication: Hypertension
    Start date: 2001-05-19
    End date: 2002-05-19

Elavil
    Dosage: 150 mg
    Indication: Depression
    Start date: 2001-05-19
    End date: 2002-05-19

Flexeril
    Dosage: 10 mg
    Indication: Back Pain
    Start date: 2001-05-19
    End date: 2002-05-19

Flexeril
    Dosage: 10 mg
    Indication: Hypertension
    Start date: 2001-05-19
    End date: 2002-05-19

Possible Darvon side effects / adverse reactions in 48 year old female

Reported by a physician from United States on 2010-02-02

Patient: 48 year old female

Reactions: Completed Suicide

Adverse event resulted in: death

Suspect drug(s):
Benzodiazepine
    Dosage: po
    Administration route: Oral
    End date: 2008-01-01

Darvon
    Dosage: po
    Administration route: Oral
    End date: 2008-01-01

Lithium
    Dosage: po
    Administration route: Oral
    End date: 2008-01-01

Methadone
    Dosage: po
    Administration route: Oral
    End date: 2008-01-01

Quetiapine
    Dosage: po
    Administration route: Oral
    End date: 2008-01-01

Roxicodone
    Dosage: po
    Administration route: Oral
    End date: 2008-01-01

Tricyclic Antidepressant
    Dosage: po
    Administration route: Oral
    End date: 2008-01-01

Varenicline
    Dosage: po
    Administration route: Oral
    End date: 2008-01-01

Venlafaxine
    Dosage: po
    Administration route: Oral
    End date: 2008-01-01

Possible Darvon side effects / adverse reactions in 27 year old male

Reported by a physician from United States on 2010-02-02

Patient: 27 year old male

Reactions: Respiratory Arrest, Cardiac Arrest

Adverse event resulted in: death

Suspect drug(s):
Clonazepam
    Dosage: po
    Administration route: Oral
    End date: 2008-01-01

Darvon
    Dosage: po
    Administration route: Oral
    End date: 2008-01-01

Marijuana
    Dosage: po
    Administration route: Oral
    End date: 2008-01-01

Roxanol
    Dosage: po
    Administration route: Oral
    End date: 2008-01-01