Daraprim Related Clinical Trials
Pyrimethamine as a Treatment for Late-Onset GM2-gangliosidosis (Tay-Sachs and Sandhoff Disease) [Completed]
Pyrimethamine for the Treatment of Relapsed Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma [Recruiting]
Prevention of Congenital Toxoplasmosis With Pyrimethamine + Sulfadiazine Versus Spiramycine During Pregnancy [Recruiting]
Clinical Trial to Investigate the Pharmacokinetic/Pharmacodynamic Drug-Drug Interaction of Pyrimethamine and Metformin IR [Completed]
Therapeutic Efficacy Study of Pyrimethamine/Sulfdoxine (Fansidar®) for the Treatment of Uncomplicated Falciparum Malaria in the Peruvian Amazon [Completed]
Pharmacokinetics of Sulfadoxine-pyrimethamine Plus Amodiaquine for Intermittent Preventive Treatment in Children (IPTc) [Completed]
SOD1 Inhibition by Pyrimethamine in Familial Amyotrophic Lateral Sclerosis (ALS) [Active, not recruiting]
Gestational Sulfadoxine-pyrimethamine and Azithromycin Treatment to Prevent Preterm Birth [Completed]
Intermittent Preventive Treatment With Azithromycin-containing Regimens in Pregnant Women in Papua New Guinea [Completed]
Intermittent Treatment With Sulfadoxine-pyrimethamine for Malaria Control in Infants [Completed]
Sulfadoxine- Pyrimethamine Versus Weekly Chloroquine for Malaria Prevention in Children With Sickle Cell Anemia [Completed]
Pyrimethamine to Treat Autoimmune Lymphoproliferative Syndrome [Completed]
A Randomized Controlled Trial for Intermittent Preventive Treatment in Pregnancy With Fansidar in Solomon Islands [Terminated]
Assessment of Sulphadoxine-pyrimethamine for Intermittent Preventive Treatment of Malaria in Pregnancy in Malawi [Completed]
Efficacy of Sulphadoxine-pyrimethamine and Artemisinin-containing Combination Therapy for Malaria [Completed]
Artesunate Plus Sulfadoxine-Pyrimethamine Pharmacokinetics, Efficacy, Gametocytes Carriage and Birth Outcomes in Pregnant Women With Malaria [Active, not recruiting]
Impact IPT With Sulfadoxine-pyrimethamine or Sulfadoxine-pyrimethamine Plus Piperaquine in Schoolchildren [Completed]
The Effect of Folic Acid on Efficacy of Sulfadoxine-pyrimethamine in Pregnant Women in Western Kenya [Completed]
A Randomised Trial of Artesunate-sulfamethoxypyrazine/Pyrimethamine Versus Praziquantel for the Treatment of S. Mansoni [Completed]
A Study of Pyrimethamine in the Treatment of Infection by a Certain Parasite in HIV-Positive Patients [Completed]
Sulphadoxine-Pyrimethamine for Intermittent Preventive Treatment of Malaria in Pregnancy in Uganda [Withdrawn]
A Pilot Study of Oral Clindamycin and Pyrimethamine for the Treatment of Toxoplasmic Encephalitis in Patients With AIDS [Completed]
A Randomized Prospective Study of Pyrimethamine Therapy for Prevention of Toxoplasmic Encephalitis in HIV-Infected Individuals With Serologic Evidence of Latent Toxoplasma Gondii Infection [Completed]
Phase II Randomized Open-Label Trial of Atovaquone Plus Pyrimethamine and Atovaquone Plus Sulfadiazine for the Treatment of Acute Toxoplasmic Encephalitis [Completed]
Efficacy of Sulfadoxine-Pyrimethamine for Treating Malaria in Gabonese Children [Terminated]
Treatment of Malaria With Quinine Plus Sulfadoxine-Pyrimethamine [Completed]
Pyrimethamine, Sulfadiazine, and Leucovorin in Treating Patients With Congenital Toxoplasmosis [Recruiting]
Artesunate Plus Sulfadoxine-Pyrimethamine Versus Chloroquine for Vivax Malaria [Completed]
The Efficacy of Re-treatment With Sulfadoxine-pyrimethamine in Children [Completed]
Intermittent Preventative Treatment With Sulfadoxine-Pyrimethamine in Gambian Multigravidae [Completed]
A Study of Azithromycin Plus Pyrimethamine in the Treatment of a Brain Infection in Patients With AIDS [Completed]
Trial of Azithromycin Plus Chloroquine Versus Sulfadoxine-Pyrimethamine Plus Chloroquine for the Treatment of Uncomplicated Malaria in India [Completed]
Efficacy and Safety of Sulphadoxine-Pyrimethamine and Amodiaquine in Ghanaian Pregnant Women [Completed]
CQSP in Malawi: Chloroquine and Sulfadoxine-pyrimethamine Efficacy for the Treatment of Malaria in Malawi [Completed]
Efficacy of Chloroquine + Sulfadoxine Pyrimethamine Versus Artemether + Lumefantrine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria in the Philippines [Completed]
Artesunate+Sulfadoxine-Pyrimethamine for the Treatment of Uncomplicated Falciparum Malaria [Completed]
Pharmacokinetics, Efficacy, Gametocyte Carriage, Birth Outcomes Following Sulfadoxine-Pyrimethamine Intermittent Presumptive Treatment in Pregnant Women [Active, not recruiting]
A Comparative Study of Mefloquine and S-P as Prophylaxis Against Malaria in Pregnant HIV + Patients [Not yet recruiting]
A Comparative Study of Azithromycin and S-P as Prophylaxis in Pregnant HIV+ Patients [Not yet recruiting]
A Randomised Efficacy Study of Combination Antimalarials to Treat Uncomplicated Malaria [Completed]
Efficacy of Intermittent Screening and Treatment or Intermittent Preventive Treatment (IPT) With Dihydroartemisinin-Piperaquine, Versus IPT With Sulfadoxine-Pyrimethamine for the Control of Malaria in Pregnancy in Kenya [Active, not recruiting]
Three Alternative Drug Regimens for Malaria Seasonal Preventive Treatment in Senegal [Completed]
Seasonal Intermittent Preventive Treatment With Sulfadoxine-Pyrimethamine in Children in Mali [Completed]
Evaluate Azithromycin Plus Chloroquine And Sulfadoxine Plus Pyrimethamine Combinations For Intermittent Preventive Treatment Of Falciparum Malaria Infection In Pregnant Women In Africa [Terminated]
Sanaria PfSPZ Challenge With Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Trial to Determine Safety and Protective Efficacy of Sanaria PfSPZ Challenge With Concurrent Pyrimethamine Treatment That Inhibits Development of Asexual B... [Recruiting]
SPK Study in Afghanistan [Recruiting]
Intermittent Preventive Treatment for Malaria in Patient With Sickle Cell Disease [Completed]
Efficacy of Combination Therapy for Prevention of Effects of Malaria During Pregnancy [Completed]
Folic Acid Supplementation in Gambian Primigravidae [Completed]
Azithromycin Plus Chloroquine Versus Sulfadoxine-Pyrimethamine Plus Chloroquine For The Treatment Of Uncomplicated, Symptomatic Falciparum Malaria In Southeast Asia [Terminated]
Efficacy of Antifolates Against Malaria in HIV-infected Pregnant Women and the Emergence of Induced Resistance in Plasmodium Falciparum [Not yet recruiting]
Kilimanjaro IPTi Drug Options Trial [Completed]
Pyrimethamine and Sulfadoxine for Treatment of Autoimmune Lymphoproliferative Syndrome [Completed]
IPT and Efficacy of Sulphadoxine/Pyrimethamine and Chlorproguanil/Dapsone in 6-59 Month Old Children With Malaria. [Terminated]
A Randomised Efficacy Study of Combination Antimalarials to Treat Uncomplicated Malaria [Completed]
Combination Antimalarials in Uncomplicated Malaria [Completed]
Chemopreventive Therapy for Malaria in Ugandan Children [Completed]
Evaluation of SP Resistance and Effectiveness of IPTp in Nigeria [Recruiting]
Randomized Trial of Two Antimalarial Treatments for Clearing Low Density P.Falciparum Parasitaemia in Sudan [Completed]
Treatment of Uncomplicated Malaria in Benin [Completed]
Navrongo Drug Options for IPT in Pregnancy Trial [Completed]
Assessing the Efficacy of Four Drug Combinations as the Next First-line Therapy for Uncomplicated Malaria in Malawi [Completed]
Reducing the Effects of Malaria in Children by Administering Repeated Preventive Doses [Completed]
IPT of Malaria With SP in Different Zones of Drug Resistance in Rwanda [Completed]
Intermittent Preventive Treatment in Infant in Mali [Completed]
A Trial of Seasonal Malaria Chemoprevention Plus Azithromycin in African Children [Not yet recruiting]
Intermittent Preventive Treatment During Pregnancy in Benin [Completed]
Intermittent Preventive Treatment of Malaria in Schoolchildren [Completed]
ACT With Chloroquine, Amodiaquine & Sulphadoxine-Pyrimethamine in Pakistan [Completed]
Comparing Praziquantel Versus Artesunate + Sulfamethoxypyrazine/Pyrimethamine for Treating Schistosomiasis [Completed]
Evaluation of Alternative Antimalarial Drugs for Malaria in Pregnancy [Completed]
Prevention of Severe Anaemia in Gambian Children [Completed]
Intermittent Preventive Treatment of Malaria in HIV-Seropositive Pregnant Women in Zambia [Completed]
Chlorproguanil/Dapsone Compared With Chloroquine and SP for Vivax Malaria [Completed]
Chloroquine for Malaria in Pregnancy [Completed]
Effectiveness of Intermittent Preventive Treatment for Malaria in Children [Completed]
Primary Prophylaxis of Cerebral Toxoplasmosis in HIV-Infected Patients [Completed]
To Compare Intravitreal Clindamycin & Dexamethasone With Classic Treatment of Toxoplasmic Retinochoroiditis [Active, not recruiting]
IPTp Plus ITNs for Malaria Control in Pregnant Women [Active, not recruiting]
Toxoplasmic Encephalitis in Patients With AIDS. Treatment and Prevention of Relapse [Completed]
A Trial of Intermittent Treatment in the Prevention of Malaria in Senegalese Children [Completed]
Trial of the Effectiveness of AQ/AS, SP/AQ and SP/CQ for Uncomplicated Malaria in Gambian Children [Completed]
Prevention of Intrauterine Growth Retardation in Burkina Faso: the Malaria Component [Completed]
To Evaluate Current Efficacy of Antimalarials Used in Timika, Papua, Indonesia [Completed]
Influence of Chloroquine on HIV Viral Load Among Pregnant Women in Uganda [Completed]
New Approaches to Improve Coverage and Compliance of Antimalarial Treatment for Pregnant Women in Rural Africa [Completed]
Reducing the Burden of Malaria in HIV-uninfected Pregnant Women and Infants [Active, not recruiting]
Multi-Centre Trial Comparing Three Artemisinin-Based Combination Treatments on P. Falciparum Malaria [Completed]
Evaluation of the Public Health Impact of Seasonal Intermittent Preventive Treatment (IPT) in Children in Senegal [Enrolling by invitation]
Impact of IPT With Sulfadoxin Pyrimetamin on Pregnant Women and Their Babies Outcomes in Peri-urban Areas of Bobo-Dioulasso(Burkina Faso) [Completed]
Preventing Malaria During Pregnancy in Epidemic-Prone Areas. [Completed]
A Controlled Comparative Trial of Sulfamethoxazole-Trimethoprim Versus Aerosolized Pentamidine for Secondary Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients Receiving Azidothymidine (AZT) [Completed]
Antimalarial Drug Resistance in Mali [Completed]
Daily Co-trimoxazole Prophylaxis to Prevent Malaria in Pregnancy [Terminated]
ACT MALI: Treatment of Malaria Based on Combination Therapies [Completed]
Effect of Antimalarial Treatment on Gametocyte Carriage in Asymptomatic P. Falciparum [Completed]
Efficacy and Safety of Azithromycin and Artesunate in Pregnant Women [Completed]
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