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Daraprim (Pyrimethamine) - Current Clinical Trials


Daraprim Related Clinical Trials

Pyrimethamine as a Treatment for Late-Onset GM2-gangliosidosis (Tay-Sachs and Sandhoff Disease) [Completed]

Pyrimethamine for the Treatment of Relapsed Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma [Recruiting]

Prevention of Congenital Toxoplasmosis With Pyrimethamine + Sulfadiazine Versus Spiramycine During Pregnancy [Recruiting]

Clinical Trial to Investigate the Pharmacokinetic/Pharmacodynamic Drug-Drug Interaction of Pyrimethamine and Metformin IR [Completed]

Therapeutic Efficacy Study of Pyrimethamine/Sulfdoxine (Fansidar®) for the Treatment of Uncomplicated Falciparum Malaria in the Peruvian Amazon [Completed]

Pharmacokinetics of Sulfadoxine-pyrimethamine Plus Amodiaquine for Intermittent Preventive Treatment in Children (IPTc) [Completed]

SOD1 Inhibition by Pyrimethamine in Familial Amyotrophic Lateral Sclerosis (ALS) [Active, not recruiting]

Gestational Sulfadoxine-pyrimethamine and Azithromycin Treatment to Prevent Preterm Birth [Completed]

Intermittent Preventive Treatment With Azithromycin-containing Regimens in Pregnant Women in Papua New Guinea [Completed]

Intermittent Treatment With Sulfadoxine-pyrimethamine for Malaria Control in Infants [Completed]

Sulfadoxine- Pyrimethamine Versus Weekly Chloroquine for Malaria Prevention in Children With Sickle Cell Anemia [Completed]

Pyrimethamine to Treat Autoimmune Lymphoproliferative Syndrome [Completed]

A Randomized Controlled Trial for Intermittent Preventive Treatment in Pregnancy With Fansidar in Solomon Islands [Terminated]

Assessment of Sulphadoxine-pyrimethamine for Intermittent Preventive Treatment of Malaria in Pregnancy in Malawi [Completed]

Efficacy of Sulphadoxine-pyrimethamine and Artemisinin-containing Combination Therapy for Malaria [Completed]

Artesunate Plus Sulfadoxine-Pyrimethamine Pharmacokinetics, Efficacy, Gametocytes Carriage and Birth Outcomes in Pregnant Women With Malaria [Active, not recruiting]

Impact IPT With Sulfadoxine-pyrimethamine or Sulfadoxine-pyrimethamine Plus Piperaquine in Schoolchildren [Completed]

The Effect of Folic Acid on Efficacy of Sulfadoxine-pyrimethamine in Pregnant Women in Western Kenya [Completed]

A Randomised Trial of Artesunate-sulfamethoxypyrazine/Pyrimethamine Versus Praziquantel for the Treatment of S. Mansoni [Completed]

A Study of Pyrimethamine in the Treatment of Infection by a Certain Parasite in HIV-Positive Patients [Completed]

Sulphadoxine-Pyrimethamine for Intermittent Preventive Treatment of Malaria in Pregnancy in Uganda [Withdrawn]

A Pilot Study of Oral Clindamycin and Pyrimethamine for the Treatment of Toxoplasmic Encephalitis in Patients With AIDS [Completed]

A Randomized Prospective Study of Pyrimethamine Therapy for Prevention of Toxoplasmic Encephalitis in HIV-Infected Individuals With Serologic Evidence of Latent Toxoplasma Gondii Infection [Completed]

Phase II Randomized Open-Label Trial of Atovaquone Plus Pyrimethamine and Atovaquone Plus Sulfadiazine for the Treatment of Acute Toxoplasmic Encephalitis [Completed]

Efficacy of Sulfadoxine-Pyrimethamine for Treating Malaria in Gabonese Children [Terminated]

Treatment of Malaria With Quinine Plus Sulfadoxine-Pyrimethamine [Completed]

Pyrimethamine, Sulfadiazine, and Leucovorin in Treating Patients With Congenital Toxoplasmosis [Recruiting]

Artesunate Plus Sulfadoxine-Pyrimethamine Versus Chloroquine for Vivax Malaria [Completed]

The Efficacy of Re-treatment With Sulfadoxine-pyrimethamine in Children [Completed]

Intermittent Preventative Treatment With Sulfadoxine-Pyrimethamine in Gambian Multigravidae [Completed]

A Study of Azithromycin Plus Pyrimethamine in the Treatment of a Brain Infection in Patients With AIDS [Completed]

Trial of Azithromycin Plus Chloroquine Versus Sulfadoxine-Pyrimethamine Plus Chloroquine for the Treatment of Uncomplicated Malaria in India [Completed]

Efficacy and Safety of Sulphadoxine-Pyrimethamine and Amodiaquine in Ghanaian Pregnant Women [Completed]

CQSP in Malawi: Chloroquine and Sulfadoxine-pyrimethamine Efficacy for the Treatment of Malaria in Malawi [Completed]

Efficacy of Chloroquine + Sulfadoxine Pyrimethamine Versus Artemether + Lumefantrine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria in the Philippines [Completed]

Artesunate+Sulfadoxine-Pyrimethamine for the Treatment of Uncomplicated Falciparum Malaria [Completed]

Pharmacokinetics, Efficacy, Gametocyte Carriage, Birth Outcomes Following Sulfadoxine-Pyrimethamine Intermittent Presumptive Treatment in Pregnant Women [Active, not recruiting]

A Comparative Study of Mefloquine and S-P as Prophylaxis Against Malaria in Pregnant HIV + Patients [Not yet recruiting]

A Comparative Study of Azithromycin and S-P as Prophylaxis in Pregnant HIV+ Patients [Not yet recruiting]

A Randomised Efficacy Study of Combination Antimalarials to Treat Uncomplicated Malaria [Completed]

Efficacy of Intermittent Screening and Treatment or Intermittent Preventive Treatment (IPT) With Dihydroartemisinin-Piperaquine, Versus IPT With Sulfadoxine-Pyrimethamine for the Control of Malaria in Pregnancy in Kenya [Active, not recruiting]

Three Alternative Drug Regimens for Malaria Seasonal Preventive Treatment in Senegal [Completed]

Seasonal Intermittent Preventive Treatment With Sulfadoxine-Pyrimethamine in Children in Mali [Completed]

Evaluate Azithromycin Plus Chloroquine And Sulfadoxine Plus Pyrimethamine Combinations For Intermittent Preventive Treatment Of Falciparum Malaria Infection In Pregnant Women In Africa [Terminated]

Sanaria PfSPZ Challenge With Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Trial to Determine Safety and Protective Efficacy of Sanaria PfSPZ Challenge With Concurrent Pyrimethamine Treatment That Inhibits Development of Asexual B... [Recruiting]

SPK Study in Afghanistan [Recruiting]

Intermittent Preventive Treatment for Malaria in Patient With Sickle Cell Disease [Completed]

Efficacy of Combination Therapy for Prevention of Effects of Malaria During Pregnancy [Completed]

Folic Acid Supplementation in Gambian Primigravidae [Completed]

Azithromycin Plus Chloroquine Versus Sulfadoxine-Pyrimethamine Plus Chloroquine For The Treatment Of Uncomplicated, Symptomatic Falciparum Malaria In Southeast Asia [Terminated]

Efficacy of Antifolates Against Malaria in HIV-infected Pregnant Women and the Emergence of Induced Resistance in Plasmodium Falciparum [Not yet recruiting]

Kilimanjaro IPTi Drug Options Trial [Completed]

Pyrimethamine and Sulfadoxine for Treatment of Autoimmune Lymphoproliferative Syndrome [Completed]

IPT and Efficacy of Sulphadoxine/Pyrimethamine and Chlorproguanil/Dapsone in 6-59 Month Old Children With Malaria. [Terminated]

A Randomised Efficacy Study of Combination Antimalarials to Treat Uncomplicated Malaria [Completed]

Combination Antimalarials in Uncomplicated Malaria [Completed]

Chemopreventive Therapy for Malaria in Ugandan Children [Completed]

Evaluation of SP Resistance and Effectiveness of IPTp in Nigeria [Recruiting]

Randomized Trial of Two Antimalarial Treatments for Clearing Low Density P.Falciparum Parasitaemia in Sudan [Completed]

Treatment of Uncomplicated Malaria in Benin [Completed]

Navrongo Drug Options for IPT in Pregnancy Trial [Completed]

Assessing the Efficacy of Four Drug Combinations as the Next First-line Therapy for Uncomplicated Malaria in Malawi [Completed]

Reducing the Effects of Malaria in Children by Administering Repeated Preventive Doses [Completed]

IPT of Malaria With SP in Different Zones of Drug Resistance in Rwanda [Completed]

Intermittent Preventive Treatment in Infant in Mali [Completed]

A Trial of Seasonal Malaria Chemoprevention Plus Azithromycin in African Children [Not yet recruiting]

Intermittent Preventive Treatment During Pregnancy in Benin [Completed]

Intermittent Preventive Treatment of Malaria in Schoolchildren [Completed]

ACT With Chloroquine, Amodiaquine & Sulphadoxine-Pyrimethamine in Pakistan [Completed]

Comparing Praziquantel Versus Artesunate + Sulfamethoxypyrazine/Pyrimethamine for Treating Schistosomiasis [Completed]

Evaluation of Alternative Antimalarial Drugs for Malaria in Pregnancy [Completed]

Prevention of Severe Anaemia in Gambian Children [Completed]

Intermittent Preventive Treatment of Malaria in HIV-Seropositive Pregnant Women in Zambia [Completed]

Chlorproguanil/Dapsone Compared With Chloroquine and SP for Vivax Malaria [Completed]

Chloroquine for Malaria in Pregnancy [Completed]

Effectiveness of Intermittent Preventive Treatment for Malaria in Children [Completed]

Primary Prophylaxis of Cerebral Toxoplasmosis in HIV-Infected Patients [Completed]

To Compare Intravitreal Clindamycin & Dexamethasone With Classic Treatment of Toxoplasmic Retinochoroiditis [Active, not recruiting]

IPTp Plus ITNs for Malaria Control in Pregnant Women [Active, not recruiting]

Toxoplasmic Encephalitis in Patients With AIDS. Treatment and Prevention of Relapse [Completed]

A Trial of Intermittent Treatment in the Prevention of Malaria in Senegalese Children [Completed]

Trial of the Effectiveness of AQ/AS, SP/AQ and SP/CQ for Uncomplicated Malaria in Gambian Children [Completed]

Prevention of Intrauterine Growth Retardation in Burkina Faso: the Malaria Component [Completed]

To Evaluate Current Efficacy of Antimalarials Used in Timika, Papua, Indonesia [Completed]

Influence of Chloroquine on HIV Viral Load Among Pregnant Women in Uganda [Completed]

New Approaches to Improve Coverage and Compliance of Antimalarial Treatment for Pregnant Women in Rural Africa [Completed]

Reducing the Burden of Malaria in HIV-uninfected Pregnant Women and Infants [Active, not recruiting]

Multi-Centre Trial Comparing Three Artemisinin-Based Combination Treatments on P. Falciparum Malaria [Completed]

Evaluation of the Public Health Impact of Seasonal Intermittent Preventive Treatment (IPT) in Children in Senegal [Enrolling by invitation]

Impact of IPT With Sulfadoxin Pyrimetamin on Pregnant Women and Their Babies Outcomes in Peri-urban Areas of Bobo-Dioulasso(Burkina Faso) [Completed]

Preventing Malaria During Pregnancy in Epidemic-Prone Areas. [Completed]

A Controlled Comparative Trial of Sulfamethoxazole-Trimethoprim Versus Aerosolized Pentamidine for Secondary Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients Receiving Azidothymidine (AZT) [Completed]

Antimalarial Drug Resistance in Mali [Completed]

Daily Co-trimoxazole Prophylaxis to Prevent Malaria in Pregnancy [Terminated]

ACT MALI: Treatment of Malaria Based on Combination Therapies [Completed]

Effect of Antimalarial Treatment on Gametocyte Carriage in Asymptomatic P. Falciparum [Completed]

Efficacy and Safety of Azithromycin and Artesunate in Pregnant Women [Completed]

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