Daranide (Dichlorphenamide) - Indications and Dosage

INDICATIONS AND USAGE

For adjunctive treatment of: chronic simple (open-angle) glaucoma, secondary glaucoma, and preoperatively in acute angle-closure glaucoma where delay of surgery is desired in order to lower intraocular pressure.

DOSAGE AND ADMINISTRATION

DARANIDE is usually given in conjunction with topical ocular hypotensive agents. In acute angle-closure glaucoma, it may be used together with miotics and osmotic agents in an attempt to reduce intraocular tension rapidly. If this is not quickly relieved, surgery may be mandatory.

Dosage must be adjusted carefully to meet the requirements of the individual patient. A priming dose of 100 to 200 mg of DARANIDE (2 to 4 tablets) is suggested for adults, followed by 100 mg (2 tablets) every 12 hours until the desired response has been obtained. The recommended maintenance dosage for adults is 25 to 50 mg (¹[sol ]₂ to 1 tablet) once to three times daily.

HOW SUPPLIED

No. 3256--Tablets DARANIDE, 50 mg each, are yellow, round, scored, compressed tablets, coded MSD 49 on one side and DARANIDE on the other. They are supplied as follows:

NDC 0006-0049-68 bottles of 100.

7870319 Issued October 1996

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