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Dalmane (Flurazepam Hydrochloride) - Published Studies


Dalmane Related Published Studies

Well-designed clinical trials related to Dalmane (Flurazepam)

A double-blind, placebo- and flurazepam-controlled investigation of the residual psychomotor and cognitive effects of modified release zolpidem in young healthy volunteers. [2006.06]

Effects of flurazepam and zolpidem on the perception of sleep in insomniacs. [1995.02]

Effects of estazolam and flurazepam on cardiopulmonary function in patients with chronic obstructive pulmonary disease. [1992.03]

Objective measurements of daytime sleepiness and performance comparing quazepam with flurazepam in two adult populations using the Multiple Sleep Latency Test. [1991.09]

Hypnotic efficacy of estazolam compared with flurazepam in outpatients with insomnia. [1991.08]

Differential side effect profile of triazolam versus flurazepam in elderly patients undergoing rehabilitation therapy. [1991.02]

Zopiclone versus flurazepam in insomnia: prolonged administration and withdrawal. [1990.10]

Cognitive performance and mood in patients with chronic insomnia during 14-day use of flurazepam and midazolam. [1990.08]

Sleep evaluation in chronic insomniacs during 14-day use of flurazepam and midazolam. [1990.08]

Clinical safety of flurazepam and midazolam during 14-day use in chronic insomniacs. [1990.08]

Sleep, performance, and plasma levels in chronic insomniacs during 14-day use of flurazepam and midazolam: methodology. [1990.08]

Sleep, performance, and plasma levels in chronic insomniacs during 14-day use of flurazepam and midazolam: an introduction. [1990.08]

Estazolam and flurazepam: a multicenter, placebo-controlled comparative study in outpatients with insomnia. [1990.05]

A comparison of the efficacy, tolerance and residual effects of zopiclone, flurazepam and placebo in insomniac outpatients. [1990.04]

A comparative study on the effects of brotizolam and flurazepam on sleep and performance in the elderly. [1989.08]

Pharmacokinetic determinants of dynamic differences among three benzodiazepine hypnotics. Flurazepam, temazepam, and triazolam. [1989.04]

Well-designed clinical trials possibly related to Dalmane (Flurazepam)

Effect of hypnotic drugs on body balance and standing steadiness. [2010]

Sleep maintenance insomnia: strengths and weaknesses of current pharmacologic therapies. [2006.01]

Effects of itraconazole on the plasma kinetics of quazepam and its two active metabolites after a single oral dose of the drug. [2003.08]

Behavioral and hypnotic treatments for insomnia subtypes. [2003]

Lack of residual sedation following middle-of-the-night zaleplon administration in sleep maintenance insomnia. [2000.01]

A dose-range finding study of zopiclone in insomniac patients. [1990.04]

Daytime sleepiness, performance, mood, nocturnal sleep: the effect of benzodiazepine and caffeine on their relationship. [1990.04]

The influence of age-dependent pharmacokinetics on the pharmacodynamics of hypnotic drugs: comparison of two hypnotics with different half-lives. [1989.03]

Other research related to Dalmane (Flurazepam)

Genetically inbred Balb/C mice are more sensitive to an effect of flurazepam and more resistant to an effect of stress than a genetically outbred mouse strain. [2009.11]

An epigenetic intervention interacts with genetic strain differences to modulate the stress-induced reduction of flurazepam's antiseizure efficacy in the mouse. [2009.06]

Next-day residual effects of gaboxadol and flurazepam administered at bedtime: a randomized double-blind study in healthy elderly subjects. [2009.01]

Acute flurazepam intoxication: a case report. [2006.03]

Toxic epidermal necrolysis caused by flurazepam? [2005.12]

Flurazepam toxicosis in two dogs. [1997.12]

A fatality due to flurazepam. [1994.11]

Decreased expression of gamma-aminobutyric acid type A/benzodiazepine receptor beta subunit mRNAs in brain of flurazepam-tolerant rats. [1994.09]

Characterization of substantia nigra pars reticulata neurons based on response to iontophoretically applied GABA and flurazepam. [1993]

Behavioral tolerance to flurazepam. [1991.04]

Plasma concentrations of flurazepam and midazolam in chronic insomniacs during 14-day use and their relationship to therapeutic effects and next-day performance and mood. [1990.08]

Psychomotor performance in chronic insomniacs during 14-day use of flurazepam and midazolam. [1990.08]

Characteristics of chronic insomniacs examined in a multicenter 14-day study of flurazepam and midazolam. [1990.08]

Depot testosterone attenuates the anticonvulsant effect of flurazepam in mice. [1990]

Repeated dose effects of lormetazepam and flurazepam upon driving performance. [1990]

[Effects of flurazepam on disturbed sleep in patients with AIDS] [1989.12]

The effectiveness of flurazepam as night sedation prior to the removal of third molars. [1988.12]

Differential response to flurazepam in long-sleep and short-sleep mice. [1988.10]

Anaesthetic effects of flurazepam alone and in combination with thiopental or hexobarbital evaluated with an EEG-threshold method in male rats. [1988.03]

Comparison of lorazepam and flurazepam as hypnotic agents in chronic insomniacs. [1988.01]

Effects of flurazepam on sleep, arousal threshold, and the perception of being asleep. [1988]

Hepatic vs. gastrointestinal presystemic extraction of oral midazolam and flurazepam. [1987.12]

Effects of flurazepam and zopiclone on the performance of chronic insomniac patients: a study of ethanol-drug interaction. [1987]

Other possibly related research studies

H3 agonist immepip markedly reduces cortical histamine release, but only weakly promotes sleep in the rat. [2003.08]

Role of protein kinase A in GABAA receptor dysfunction in CA1 pyramidal cells following chronic benzodiazepine treatment. [2003.05]

Pharmacodynamic profile of Zaleplon, a new non-benzodiazepine hypnotic agent. [2001.07]

Effects of striatal injections of GABA(A) receptor agonists and antagonists in a genetic animal model of paroxysmal dystonia. [2002.05.17]

Chronic benzodiazepine agonist treatment produces functional uncoupling of the gamma-aminobutyric acid-benzodiazepine receptor ionophore complex in cortical neurons. [1994.04]

Management of insomnia in office-based practice. National prevalence and therapeutic patterns. [1993.11]

Oral benzodiazepines and conscious sedation: a review. [1992.09]

Diagnosis and treatment of outpatient insomnia by psychiatric and nonpsychiatric physicians. [1992.07]

Insomnia in the elderly. [1992.06]

Clinical uses and advantages of low doses of benzodiazepine hypnotics. [1992.06]

Pharmacology of benzodiazepine hypnotics. [1992.06]

Chronic benzodiazepine treatment of rats induces reduction of paired-pulse inhibition in CA1 region of in vitro hippocampus. [1991.10.04]

A review of the safety profiles of benzodiazepine hypnotics. [1991.09]

The beneficial and adverse effects of hypnotics. [1991.07]

Avoiding the blanket approach to insomnia. Targeted therapy for specific causes. [1991.07]

Ultradian dynamics of sleep after a single dose of benzodiazepine hypnotics. [1991.03.19]

Propranolol does not alter flutoprazepam kinetics and metabolism in the rat. [1991.01]

Failure to limit quantities of benzodiazepine hypnotic drugs for outpatients: placing the elderly at risk. [1990.12]

Evaluation of experimental combined toxicity by use of dose-frequency curves: comparison with theoretical additivity as well as independence. [1990.10]

Effects of patient age and physician training on choice and dose of benzodiazepine hypnotic drugs. [1990.02]

Regional GABA/benzodiazepine receptor/chloride channel coupling after acute and chronic benzodiazepine treatment. [1989.08.11]

Rebound insomnia: a critical review. [1989.06]

Longitudinal study on pharmacodynamics and pharmacokinetics of acute, steady-state and withdrawn quazepam. [1989.02]

Delirium after elective orthopedic surgery: risk factors and natural history. [1989]

Modulation of GABA-gated chloride ion flux in rat brain by acute and chronic benzodiazepine administration. [1988.07]

Liquid chromatographic assay and pharmacokinetics of quazepam and its metabolites following sublingual administration of quazepam. [1988.06]

Chronic benzodiazepine treatment increases the effects of the inverse agonist FG7142. [1988.04]

Behavioral measurement of benzodiazepine tolerance and GABAergic subsensitivity in the substantia nigra pars reticulata. [1988.01.12]

Hypernatraemia and hyperchloraemic acidosis after bleach ingestion. [1988.01]

The use of benzodiazepine hypnotics in the elderly. [1988]

Hypothermia induced by baclofen, a possible index of GABAB receptor function in mice, is enhanced by antidepressant drugs and ECS. [1987.12]

Obtundation in the elderly patient: presentation of a drug overdose. [1987.11]

Bidirectional effects of chronic treatment with agonists and inverse agonists at the benzodiazepine receptor. [1987.09]

Sleep induction by an adrenal steroid in the rat. [1987]

Adverse reactions to benzodiazepine hypnotics: spontaneous reporting system. [1987]

Hypnotic residual effects of benzodiazepines with repeated administration. [1986.06]

A 5-year prospective assessment of the risk associated with individual benzodiazepines and doses in new elderly users. [2005.02]

Quetiapine in hospitalized patients with schizophrenia refractory to treatment with first-generation antipsychotics: a 4-week, flexible-dose, single-blind, exploratory, pilot trial. [2004.08.01]

Transient plasticity of hippocampal CA1 neuron glutamate receptors contributes to benzodiazepine withdrawal-anxiety. [2004.11]

Residual effects of hypnotics: epidemiology and clinical implications. [2004]

The continuing challenge of inappropriate prescribing in the elderly: an update of the evidence. [2002.11]

Insomnia in children: when are hypnotics indicated? [2002]

The need for flexibility in dosing of hypnotic agents. [2000.02.01]

Zaleplon: a pyrazolopyrimidine sedative-hypnotic agent for the treatment of insomnia. [2000.11]

[Acute lipoid pneumonia caused by accidental aspiration of vaseline used in nasogastric intubation] [2000.09]

Zolpidem: an update of its pharmacology, therapeutic efficacy and tolerability in the treatment of insomnia. [2000.04]

A comparative assessment of the risks and benefits of zopiclone: a review of 15 years' clinical experience. [1999.12]

Rhabdomyolysis-induced acute renal failure after morphine overdose--a case report. [1999.09]

Management of insomnia. [1999.09]

High-dose discrimination training with midazolam: context determines generalization profile. [1999.10]

Anticonvulsant properties of 1,4-benzodiazepine derivatives in amygdaloid-kindled seizures and their chemical structure-related anticonvulsant action. [1998.11]

Psychotropic prescribing for the elderly in office-based practice. [1998.05]

Zopiclone. An update of its pharmacology, clinical efficacy and tolerability in the treatment of insomnia. [1998.02]

The effects of fentanyl and sufentanil on cerebral hemodynamics. [1997.07]

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