DALMANE SUMMARY
Dalmane is available as capsules containing 15 mg or 30 mg flurazepam hydrochloride.
Dalmane is a hypnotic agent useful for the treatment of insomnia characterized by difficulty in falling asleep, frequent nocturnal awakenings, and/or early morning awakening. Dalmane can be used effectively in patients with recurring insomnia or poor sleeping habits, and in acute or chronic medical situations requiring restful sleep. Sleep laboratory studies have objectively determined that Dalmane is effective for at least 28 consecutive nights of drug administration. Since insomnia is ofter transient and intermittent, short-term use is usually sufficient. Prolonged use of hypnotics is usually not indicated and should only be undertaken concomitantly with appropriate evaluation of the patient.
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NEWS HIGHLIGHTSMedia Articles Related to Dalmane (Flurazepam)
Relationship Between Sleep Duration And Suicidal Thoughts In People With Insomnia. Source: Health News from Medical News Today [2013.05.17] Results of a new study show that every one-hour increase in sleep duration was associated with a 72 percent decrease in the likelihood of moderate or high suicide risk, in comparison with low risk. Data were adjusted for age, gender, race/ethnicity, education and age of onset of sleep difficulties. "We were surprised by the strength of the association between sleep duration and suicide risk," said primary author Linden Oliver, MA, clinical research coordinator for the University of Pennsylvania Behavioral Sleep Medicine Research Program in Philadelphia, Pa...
Insomnia Can Lead To Future Hospitalization And Increased Health Service Use Source: Seniors / Aging News From Medical News Today [2013.05.14] Having trouble falling or staying asleep? According to a new study led by a team of researchers at the Johns Hopkins Bloomberg School of Public Health, insomnia may be an important indicator of future hospitalization among middle-aged and older adults...
A Woman's Risk Of Heart Disease May Be Increased By Insomnia And Disrupted Sleep During Menopause Source: Sleep / Sleep Disorders / Insomnia News From Medical News Today [2013.05.13] Insomnia and other sleep disturbances are common among perimenopausal and postmenopausal women and may increase their risk of coronary heart disease (CHD) and cardiovascular disease (CVD)...
Making Sense Of The Neurobiology Of Restless Legs Syndrome And Related Insomnia Source: Sleep / Sleep Disorders / Insomnia News From Medical News Today [2013.05.09] Johns Hopkins researchers believe they may have discovered an explanation for the sleepless nights associated with restless legs syndrome (RLS), a symptom that persists even when the disruptive, overwhelming nocturnal urge to move the legs is treated successfully with medication...
Insomnia May Raise Risk of Heart Attack, Stroke Source: MedicineNet Hyperthyroidism Specialty [2012.11.05] Title: Insomnia May Raise Risk of Heart Attack, Stroke Category: Health News Created: 11/4/2012 8:35:00 PM Last Editorial Review: 11/5/2012 12:00:00 AM
Published Studies Related to Dalmane (Flurazepam)
A double-blind, placebo- and flurazepam-controlled investigation of the residual psychomotor and cognitive effects of modified release zolpidem in young healthy volunteers. [2006.06] Short-acting hypnotic drugs, such as zolpidem, have minimal residual effects but may not provide optimal efficacy throughout the night for all insomnia patients... In conclusion, the study showed the good tolerance of zolpidem-MR in terms of residual neuropsychological effects as well as a beneficial effect on sleep quality in young healthy adults.
Effects of flurazepam and zolpidem on the perception of sleep in insomniacs. [1995.02] We have shown previously that the benzodiazepine hypnotic triazolam alters the perception of being awake or asleep in insomniacs, making it more likely that they will report having been asleep when awakened by an electronic tone at various times of the night... These findings suggest that drug-induced alterations in the perception of being awake or asleep are not unique to benzodiazepines, but occur with the nonbenzodiazepine zolpidem as well.
Effects of estazolam and flurazepam on cardiopulmonary function in patients with chronic obstructive pulmonary disease. [1992.03] Benzodiazepine drugs have been shown to suppress respiratory function in patients with chronic obstructive pulmonary disease (COPD). We designed a placebo-controlled crossover study to compare the effects of a new benzodiazepine, estazolam ('ProSom'), with those of flurazepam ('Dalmane') on cardiopulmonary function in COPD patients...
Objective measurements of daytime sleepiness and performance comparing quazepam with flurazepam in two adult populations using the Multiple Sleep Latency Test. [1991.09] Daytime residual drowsiness and psychomotor performance were assessed for two long half-life benzodiazepines, quazepam and flurazepam, in two randomized, parallel, and double-blind studies in insomniacs... Thus, quazepam 15 mg produces less daytime somnolence and fewer psychomotor performance decrements than does flurazepam.
Hypnotic efficacy of estazolam compared with flurazepam in outpatients with insomnia. [1991.08] Estazolam is a new benzodiazepine hypnotic agent with an intermediate half-life of 12 to 15 hours... Estazolam 1 mg is also effective in the treatment of outpatients with insomnia, but to a lesser degree.
Clinical Trials Related to Dalmane (Flurazepam)
Residual Effects of Zolpidem Tartrate Extended Release and Eszopiclone Vs Placebo [Completed]
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