Cymbalta Related Published Studies
Well-designed clinical trials related to Cymbalta (Duloxetine)
Pharmacokinetics of orally administered duloxetine in children and adolescents
with major depressive disorder. [2014]
Efficacy of duloxetine versus alternative oral therapies: an indirect comparison
of randomised clinical trials in chronic low back pain. [2013]
Effect of duloxetine on pain, function, and quality of life among patients with
chemotherapy-induced painful peripheral neuropathy: a randomized clinical trial. [2013]
Responsiveness of the Intermittent and Constant Osteoarthritis Pain (ICOAP) scale
in a trial of duloxetine for treatment of osteoarthritis knee pain. [2013]
Safety and tolerability of duloxetine in elderly patients with major depressive
disorder: a pooled analysis of two placebo-controlled studies. [2013]
The effect of duloxetine treatment on cognition in patients with fibromyalgia. [2012]
Evaluation of patient-rated stiffness associated with fibromyalgia: a post-hoc
analysis of 4 pooled, randomized clinical trials of duloxetine. [2012]
Time course of improvement of different symptom clusters in patients with major
depression and pain treated with duloxetine or placebo. [2012]
Duloxetine in the treatment of binge eating disorder with depressive disorders: a
placebo-controlled trial. [2012]
Duloxetine added to oral nonsteroidal anti-inflammatory drugs for treatment of knee pain due to osteoarthritis: results of a randomized, double-blind, placebo-controlled trial. [2011.12]
Duloxetine as adjunctive treatment to clozapine in patients with schizophrenia: a randomized, placebo-controlled trial. [2011.11]
A randomized placebo-controlled trial of duloxetine in patients with major depressive disorder and associated painful physical symptoms. [2011.10]
Efficacy and safety of duloxetine 60 mg and 120 mg daily in patients hospitalized for severe depression: a double-blind randomized trial. [2011.08]
Duloxetine, pregabalin, and duloxetine plus gabapentin for diabetic peripheral neuropathic pain management in patients with inadequate pain response to gabapentin: an open-label, randomized, noninferiority comparison. [2011.07]
Improvement in multiple dimensions of fatigue in patients with fibromyalgia treated with duloxetine: secondary analysis of a randomized, placebo-controlled trial. [2011.06.13]
A comparative evaluation of amitriptyline and duloxetine in painful diabetic neuropathy: a randomized, double-blind, cross-over clinical trial. [2011.04]
Subchronic duloxetine administration alters the extended amygdala circuitry in healthy individuals. [2011.03.15]
Sexual function during long-term duloxetine treatment in patients with recurrent major depressive disorder. [2011.03]
Duloxetine in patients with central neuropathic pain caused by spinal cord injury or stroke: a randomized, double-blind, placebo-controlled trial. [2011.02]
Duloxetine for mild to moderate postprostatectomy incontinence: preliminary results of a randomised, placebo-controlled trial. [2011.01]
A double-blind, randomized, placebo-controlled study of the efficacy and safety of duloxetine for the treatment of chronic pain due to osteoarthritis of the knee. [2011.01]
Trajectories of depression severity in clinical trials of duloxetine: insights
into antidepressant and placebo responses. [2011]
Duloxetine as adjunctive treatment to clozapine in patients with schizophrenia: a
randomized, placebo-controlled trial. [2011]
A comparative evaluation of amitriptyline and duloxetine in painful diabetic
neuropathy: a randomized, double-blind, cross-over clinical trial. [2011]
Comparative pain and mood effects in patients with comorbid fibromyalgia and
major depressive disorder: secondary analyses of four pooled randomized
controlled trials of duloxetine. [2011]
Flexible dosed duloxetine in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled trial. [2010.12]
Duloxetine versus placebo in patients with chronic low back pain: a 12-week, fixed-dose, randomized, double-blind trial. [2010.12]
Duloxetine versus placebo in the treatment of patients with diabetic neuropathic pain in China. [2010.11]
Flexible Dosed Duloxetine in the Treatment of Fibromyalgia: A Randomized, Double-blind, Placebo-controlled Trial. [2010.09.15]
Duloxetine reduces morphine requirements after knee replacement surgery. [2010.09]
A Double-blind, Randomized, Placebo-controlled Study of the Efficacy and Safety of Duloxetine for the Treatment of Chronic Pain Due to Osteoarthritis of the Knee. [2010.07.05]
Duloxetine for the treatment of generalized social anxiety disorder: a preliminary randomized trial of increased dose to optimize response. [2010.07]
Pain response profile of patients with fibromyalgia treated with duloxetine. [2010.07]
Efficacy and safety of duloxetine in patients with chronic low back pain. [2010.06.01]
Failure to replicate genetic associations with antidepressant treatment response in duloxetine-treated patients. [2010.06.01]
Long-term safety, tolerability, and efficacy of duloxetine in the treatment of fibromyalgia. [2010.06]
Duloxetine Versus Placebo in Patients With Chronic Low Back Pain: A 12-Week, Fixed-Dose, Randomized, Double-Blind Trial. [2010.05.14]
Effects of varying degrees of renal impairment on the pharmacokinetics of duloxetine: analysis of a single-dose phase I study and pooled steady-state data from phase II/III trials. [2010.05.01]
Escitalopram 20 mg versus duloxetine 60 mg for the treatment of chronic low back pain. [2010.05]
Urinary flow and urinary symptoms in elderly males exposed to either escitalopram or duloxetine. [2010.05]
Maintenance of effect of duloxetine in patients with chronic low back pain: a 41-week uncontrolled, dose-blinded study. [2010.05]
Duloxetine 60 mg/day for the prevention of depressive recurrences: post hoc analyses from a recurrence prevention study. [2010.05]
Short- and long-term efficacy and safety of duloxetine in women with predominant stress urinary incontinence. [2010.02]
Duloxetine versus venlafaxine in the treatment of unipolar and bipolar depression. [2010]
Pain response profile of patients with fibromyalgia treated with duloxetine. [2010]
Maintenance of effect of duloxetine in patients with chronic low back pain: a
41-week uncontrolled, dose-blinded study. [2010]
Safety and tolerability of duloxetine in the acute management of diabetic
peripheral neuropathic pain: analysis of pooled data from three
placebo-controlled clinical trials. [2010]
Efficacy and safety of duloxetine in patients with chronic low back pain. [2010]
Effects of varying degrees of renal impairment on the pharmacokinetics of
duloxetine: analysis of a single-dose phase I study and pooled steady-state data
from phase II/III trials. [2010]
Duloxetine 60 mg/day for the prevention of depressive recurrences: post hoc
analyses from a recurrence prevention study. [2010]
Failure to replicate genetic associations with antidepressant treatment response
in duloxetine-treated patients. [2010]
The clinical importance of changes in the 0 to 10 numeric rating scale for worst,
least, and average pain intensity: analyses of data from clinical trials of
duloxetine in pain disorders. [2010]
Long-term safety, tolerability, and efficacy of duloxetine in the treatment of
fibromyalgia. [2010]
Effects of duloxetine on the pharmacodynamics and pharmacokinetics of warfarin at steady state in healthy subjects. [2009.12]
Duloxetine, a centrally acting analgesic, in the treatment of patients with osteoarthritis knee pain: a 13-week, randomized, placebo-controlled trial. [2009.12]
A six-month double-blind, placebo-controlled, randomized clinical trial of duloxetine for the treatment of fibromyalgia. [2009.11.30]
A double-blind, randomized trial of duloxetine versus placebo in the management of chronic low back pain. [2009.09]
Safety and tolerability of duloxetine treatment of diabetic peripheral neuropathic pain between patients with and without cardiovascular conditions. [2009.09]
Duloxetine, a centrally acting analgesic, in the treatment of patients with osteoarthritis knee pain: A 13-week, randomized, placebo-controlled trial. [2009.07.20]
Duloxetine for the treatment of recurrent major depressive disorder in elderly patients: treatment outcomes in patients with comorbid arthritis. [2009.07]
A 1-year safety and efficacy study of duloxetine in patients with fibromyalgia. [2009.06]
Variation in catechol-O-methyltransferase is associated with duloxetine response in a clinical trial for major depressive disorder. [2009.05.01]
Duloxetine in the prevention of depressive recurrences: a randomized, double-blind, placebo-controlled trial. [2009.05]
Pharmacokinetics of duloxetine hydrochloride enteric-coated tablets in healthy Chinese volunteers: a randomized, open-label, single- and multiple-dose study. [2009.05]
Brain functional changes and duloxetine treatment response in fibromyalgia: a pilot study. [2009.05]
Extended release quetiapine fumarate monotherapy in major depressive disorder: a placebo- and duloxetine-controlled study. [2009.04]
Predictors of relapse in a study of duloxetine treatment in patients with major depressive disorder. [2009.03]
Switching to duloxetine in selective serotonin reuptake inhibitor non- and partial-responders: effects on painful physical symptoms of depression. [2009.02]
Improvement of psychic and somatic symptoms in adult patients with generalized anxiety disorder: examination from a duloxetine, venlafaxine extended-release and placebo-controlled trial. [2009.02]
Duloxetine: a review of its use in the treatment of generalized anxiety disorder. [2009]
An assessment of drug-drug interactions: the effect of desvenlafaxine and duloxetine on the pharmacokinetics of the CYP2D6 probe desipramine in healthy subjects. [2008.12]
Early improvement during duloxetine treatment of generalized anxiety disorder predicts response and remission at endpoint. [2008.10]
Factors predicting reduced antidepressant response: experience with the SNRI duloxetine in patients with major depression. [2008.10]
The effect of pain on outcomes in a trial of duloxetine treatment of major depressive disorder. [2008.10]
Duloxetine treatment for relapse prevention in adults with generalized anxiety disorder: a double-blind placebo-controlled trial. [2008.09]
A randomized, double-blind study of increasing or maintaining duloxetine dose in patients without remission of major depressive disorder after initial duloxetine therapy. [2008.09]
Long-term efficacy of duloxetine in women with stress urinary incontinence. [2008.07]
Efficacy and safety of duloxetine in elderly women with stress urinary incontinence or stress-predominant mixed urinary incontinence. [2008.06.20]
Efficacy and safety of duloxetine for treatment of fibromyalgia in patients with or without major depressive disorder: Results from a 6-month, randomized, double-blind, placebo-controlled, fixed-dose trial. [2008.06]
A randomized, controlled trial of duloxetine alone vs. duloxetine plus a telephone intervention in the treatment of depression. [2008.05]
Time to response for duloxetine 60 mg once daily versus placebo in elderly patients with major depressive disorder. [2008.04]
Duloxetine versus placebo for the treatment of women with stress predominant urinary incontinence in Taiwan: a double-blind, randomized, placebo-controlled trial. [2008.01.25]
A randomized, double-blind comparison of duloxetine and venlafaxine in the treatment of patients with major depressive disorder. [2008.01]
In vitro and in vivo evaluations of cytochrome P450 1A2 interactions with duloxetine. [2008]
Duloxetine compared with placebo for the treatment of women with mixed urinary incontinence. [2008]
Efficacy and safety of duloxetine in the treatment of generalized anxiety disorder: a flexible-dose, progressive-titration, placebo-controlled trial. [2008]
Implications of Pain in Generalized Anxiety Disorder: Efficacy of Duloxetine. [2008]
Long-term tolerability and effectiveness of duloxetine in the treatment of major depressive disorder. [2008]
Efficacy and safety of duloxetine 60 mg once daily in the treatment of pain in patients with major depressive disorder and at least moderate pain of unknown etiology: a randomized controlled trial. [2007.11]
A randomized, controlled trial of duloxetine alone vs. duloxetine plus a telephone intervention in the treatment of depression. [2007.09.28]
An open-label 52-week clinical extension comparing duloxetine with routine care in patients with diabetic peripheral neuropathic pain. [2007.09]
Duloxetine compared with placebo for treating women with symptoms of overactive bladder. [2007.08]
Effect of dose escalation on the tolerability and efficacy of duloxetine in the treatment of women with stress urinary incontinence. [2007.08]
Duloxetine increases stage 3 sleep and suppresses rapid eye movement (REM) sleep in patients with major depression. [2007.07]
Modafinil Augmentation of Selective Serotonin Reuptake Inhibitor Therapy in MDD Partial Responders with Persistent Fatigue and Sleepiness. [2007.07]
Once-daily duloxetine 60 mg in the treatment of major depressive disorder: Multicenter, double-blind, randomized, paroxetine-controlled, non-inferiority trial in China, Korea, Taiwan and Brazil. [2007.06]
The effects of supratherapeutic doses of duloxetine on blood pressure and pulse rate. [2007.06]
Efficacy of duloxetine on cognition, depression, and pain in elderly patients with major depressive disorder: an 8-week, double-blind, placebo-controlled trial. [2007.06]
Duloxetine versus escitalopram and placebo: an 8-month, double-blind trial in patients with major depressive disorder. [2007.06]
Duloxetine as an SNRI treatment for generalized anxiety disorder: results from a placebo and active-controlled trial. [2007.05]
Duloxetine treatment for role functioning improvement in generalized anxiety disorder: three independent studies. [2007.04]
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