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Cymbalta (Duloxetine Hydrochloride) - Published Studies

 


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Cymbalta Related Published Studies

Well-designed clinical trials related to Cymbalta (Duloxetine)

Long-term efficacy of duloxetine in women with stress urinary incontinence. [2008.07]

Efficacy and safety of duloxetine for treatment of fibromyalgia in patients with or without major depressive disorder: Results from a 6-month, randomized, double-blind, placebo-controlled, fixed-dose trial. [2008.06]

A randomized, controlled trial of duloxetine alone vs. duloxetine plus a telephone intervention in the treatment of depression. [2008.05]

Time to response for duloxetine 60 mg once daily versus placebo in elderly patients with major depressive disorder. [2008.04]

Duloxetine versus placebo for the treatment of women with stress predominant urinary incontinence in Taiwan: a double-blind, randomized, placebo-controlled trial. [2008.01.25]

A randomized, double-blind comparison of duloxetine and venlafaxine in the treatment of patients with major depressive disorder. [2008.01]

In vitro and in vivo evaluations of cytochrome P450 1A2 interactions with duloxetine. [2008]

Duloxetine compared with placebo for the treatment of women with mixed urinary incontinence. [2008]

Efficacy and safety of duloxetine in the treatment of generalized anxiety disorder: a flexible-dose, progressive-titration, placebo-controlled trial. [2008]

Implications of Pain in Generalized Anxiety Disorder: Efficacy of Duloxetine. [2008]

Long-term tolerability and effectiveness of duloxetine in the treatment of major depressive disorder. [2008]

Efficacy and safety of duloxetine 60 mg once daily in the treatment of pain in patients with major depressive disorder and at least moderate pain of unknown etiology: a randomized controlled trial. [2007.11]

A randomized, controlled trial of duloxetine alone vs. duloxetine plus a telephone intervention in the treatment of depression. [2007.09.28]

An open-label 52-week clinical extension comparing duloxetine with routine care in patients with diabetic peripheral neuropathic pain. [2007.09]

Duloxetine compared with placebo for treating women with symptoms of overactive bladder. [2007.08]

Effect of dose escalation on the tolerability and efficacy of duloxetine in the treatment of women with stress urinary incontinence. [2007.08]

Duloxetine increases stage 3 sleep and suppresses rapid eye movement (REM) sleep in patients with major depression. [2007.07]

Modafinil Augmentation of Selective Serotonin Reuptake Inhibitor Therapy in MDD Partial Responders with Persistent Fatigue and Sleepiness. [2007.07]

Once-daily duloxetine 60 mg in the treatment of major depressive disorder: Multicenter, double-blind, randomized, paroxetine-controlled, non-inferiority trial in China, Korea, Taiwan and Brazil. [2007.06]

The effects of supratherapeutic doses of duloxetine on blood pressure and pulse rate. [2007.06]

Efficacy of duloxetine on cognition, depression, and pain in elderly patients with major depressive disorder: an 8-week, double-blind, placebo-controlled trial. [2007.06]

Duloxetine versus escitalopram and placebo: an 8-month, double-blind trial in patients with major depressive disorder. [2007.06]

Duloxetine as an SNRI treatment for generalized anxiety disorder: results from a placebo and active-controlled trial. [2007.05]

Duloxetine treatment for role functioning improvement in generalized anxiety disorder: three independent studies. [2007.04]

Impact of disease characteristics on the efficacy of duloxetine in diabetic peripheral neuropathic pain. [2007.03]

Efficacy and safety of duloxetine in the treatment of generalized anxiety disorder: a flexible-dose, progressive-titration, placebo-controlled trial. [2007.02.20]

Comparison of duloxetine, escitalopram, and sertraline effects on cytochrome P450 2D6 function in healthy volunteers. [2007.02]

Pharmacokinetics and tolerability of duloxetine following oral administration to healthy Chinese subjects. [2007]

The efficacy of duloxetine in the treatment of premature ejaculation. [2007]

Duloxetine for the management of diabetic peripheral neuropathic pain: evidence-based findings from post hoc analysis of three multicenter, randomized, double-blind, placebo-controlled, parallel-group studies. [2007]

Differential antidepressant symptom efficacy: placebo-controlled comparisons of duloxetine and SSRIs (fluoxetine, paroxetine, escitalopram). [2007]

A randomized controlled trial of duloxetine in diabetic peripheral neuropathic pain. [2006.10.24]

Duloxetine in the treatment of major depressive disorder: a placebo- and paroxetine-controlled trial. [2006.09]

Duloxetine in the treatment of major depressive disorder: an assessment of the relationship between outcomes and episode characteristics. [2006.09]

Treatment benefits of duloxetine in major depressive disorder as assessed by number needed to treat. [2006.09]

Cost-effectiveness of duloxetine versus routine treatment for U.S. patients with diabetic peripheral neuropathic pain. [2006.06]

Management of depression relapse: re-initiation of duloxetine treatment or dose increase. [2006.06]

Duloxetine 60 mg once daily in the treatment of milder major depressive disorder. [2006.05]

Economic evaluation of duloxetine for the treatment of women with stress urinary incontinence: a Markov model comparing pharmacotherapy with pelvic floor muscle training. [2006.04]

Duloxetine in the prevention of relapse of major depressive disorder: double-blind placebo-controlled study. [2006.04]

Duloxetine for the treatment of stress urinary incontinence in women: an integrated analysis of safety. [2006.03.01]

Duloxetine versus routine care in the long-term management of diabetic peripheral neuropathic pain. [2006.02]

A randomized, double-blind, placebo-controlled trial of duloxetine in the treatment of women with fibromyalgia with or without major depressive disorder. [2005.12.15]

A double-blind, randomized multicenter trial comparing duloxetine with placebo in the management of diabetic peripheral neuropathic pain. [2005.09]

Impact of duloxetine on quality of life for women with symptoms of urinary incontinence. [2005.09]

Duloxetine for the treatment of major depressive disorder in women ages 40 to 55 years. [2005.07]

Duloxetine vs. placebo in patients with painful diabetic neuropathy. [2005.07]

Sexual functioning assessed in 4 double-blind placebo- and paroxetine-controlled trials of duloxetine for major depressive disorder. [2005.06]

A randomized controlled trial of duloxetine alone, pelvic floor muscle training alone, combined treatment and no active treatment in women with stress urinary incontinence. [2005.05]

Cardiovascular profile of duloxetine, a dual reuptake inhibitor of serotonin and norepinephrine. [2005.04]

Onset of action for duloxetine 60 mg once daily: double-blind, placebo-controlled studies. [2005.03]

Comparative effects of duloxetine and desipramine on sleep EEG in healthy subjects. [2005.02]

Duloxetine 60 mg once-daily in the treatment of painful physical symptoms in patients with major depressive disorder. [2005.01]

Duloxetine in the acute and long-term treatment of major depressive disorder: a placebo- and paroxetine-controlled trial. [2004.12]

Incidence and duration of antidepressant-induced nausea: duloxetine compared with paroxetine and fluoxetine. [2004.09]

A double-blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder. [2004.09]

Duloxetine: mechanism of action at the lower urinary tract and Onuf's nucleus. [2004.08]

Duloxetine in the treatment of depression: a double-blind placebo-controlled comparison with paroxetine. [2004.08]

Effect of duloxetine on tolterodine pharmacokinetics in healthy volunteers. [2004.05]

Duloxetine versus placebo in the treatment of European and Canadian women with stress urinary incontinence. [2004.03]

Duloxetine vs placebo in the treatment of stress urinary incontinence: a four-continent randomized clinical trial. [2004.02]

Effects of duloxetine on painful physical symptoms associated with depression. [2004.01]

Effect of age on the pharmacokinetics of duloxetine in women. [2004.01]

Duloxetine versus placebo for the treatment of North American women with stress urinary incontinence. [2003.10]

Duloxetine increases serotonin and norepinephrine availability in healthy subjects: a double-blind, controlled study. [2003.09]

Duloxetine in treatment of anxiety symptoms associated with depression. [2003]

Duloxetine 60 mg once daily dosing versus placebo in the acute treatment of major depression. [2002.11]

Duloxetine versus placebo in the treatment of stress urinary incontinence. [2002.07]

Duloxetine, 60 mg once daily, for major depressive disorder: a randomized double-blind placebo-controlled trial. [2002.04]

Duloxetine in the treatment of major depressive disorder: a double-blind clinical trial. [2002.03]

Assessment of the serotonin and norepinephrine reuptake blocking properties of duloxetine in healthy subjects. [2001.05]

Pharmacokinetics and safety of duloxetine, a dual-serotonin and norepinephrine reuptake inhibitor. [2000.02]

An open-label study of duloxetine hydrochloride, a mixed serotonin and noradrenaline reuptake inhibitor, in patients with DSM-III-R major depressive disorder. Lilly Duloxetine Depression Study Group. [1997.05]

Well-designed clinical trials possibly related to Cymbalta (Duloxetine)

Meta-analysis of major depressive disorder relapse and recurrence with second-generation antidepressants. [2008.10]

The relationship between functional outcomes and the treatment of anxious and painful somatic symptoms in patients with generalized anxiety disorder. [2008.09]

Minimal clinically important differences in Incontinence Quality-of-Life scores in stress urinary incontinence. [2006.06]

Efficacy and safety of second-generation antidepressants in the treatment of major depressive disorder. [2005.09.20]

Cost-effectiveness inferences from bootstrap quadrant confidence levels: three degrees of dominance. [2005]

Pharmacological treatment of women awaiting surgery for stress urinary incontinence. [2004.09]

Clinical assessment of norepinephrine transporter blockade through biochemical and pharmacological profiles. [2004.06.29]

Validation of two global impression questionnaires for incontinence. [2003.07]

Mixed urinary incontinence symptoms: urodynamic findings, incontinence severity, and treatment response. [2003.07]

Quality of life of women with urinary incontinence: further development of the incontinence quality of life instrument (I-QOL) [1999.01]

Other research related to Cymbalta (Duloxetine)

Clinical impact of duloxetine treatment on sleep in patients with major depressive disorder. [2008.11]

Duloxetine and pregabalin: safe and effective for the long-term treatment of fibromyalgia? [2008.10.14]

A Randomized, Double-Blind Study of Increasing or Maintaining Duloxetine Dose in Patients Without Remission of Major Depressive Disorder After Initial Duloxetine Therapy. [2008.07.15]

An 8-Week, Open-Label Trial of Duloxetine for Comorbid Major Depressive Disorder and Chronic Headache. [2008.07.15]

Predictors of relapse in a study of duloxetine treatment in patients with major depressive disorder. [2008.07.12]

Duloxetine for major depressive episodes in the course of psychotic disorders: an observational clinical trial. [2008.06.26]

A non-inferiority comparison of duloxetine and venlafaxine in the treatment of adult patients with generalized anxiety disorder. [2008.06]

Early improvement during duloxetine treatment of generalized anxiety disorder predicts response and remission at endpoint. [2008.03.16]

Duloxetine for premenstrual dysphoric disorder: a pilot study. [2008.03]

Safety and tolerability of duloxetine at 60 mg once daily in elderly patients with major depressive disorder. [2008.02]

Rescue Pharmacotherapy With Duloxetine for Selective Serotonin Reuptake Inhibitor Nonresponders in Late-Life Depression: Outcome and Tolerability. [2008.01.30]

Examining quality of life in patients with generalized anxiety disorder: Clinical relevance and response to duloxetine treatment. [2008.01.21]

Switching to duloxetine from selective serotonin reuptake inhibitor antidepressants: a multicenter trial comparing 2 switching techniques. [2008.01]

Duloxetine does not relieve painful physical symptoms in depression: a meta-analysis. [2008]

Escitalopram and Duloxetine in Major Depressive Disorder: A Pharmacoeconomic Comparison Using UK Cost Data. [2008]

A comparison of initial duloxetine dosing strategies in patients with major depressive disorder. [2007.12]

Differential Antidepressant Symptom Efficacy: Placebo-Controlled Comparisons of Duloxetine and SSRIs (Fluoxetine, Paroxetine, Escitalopram). [2007.11.23]

Evidence for the efficacy of duloxetine in treating mild, moderate, and severe depression. [2007.11]

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