Cutivate (Fluticasone Propionate Topical) - Description

DESCRIPTION

CUTIVATE (fluticasone propionate cream) Cream, 0.05% contains fluticasone propionate [(6(alpha),11(beta),16 (alpha),17 (alpha))-6,9,-difluoro-11-hydroxy-16-methyl- 3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid, S-fluoromethyl ester], a synthetic fluorinated corticosteroid, for topical dermatologic use. The topical corticosteroids constitute a class of primarily synthetic steroids used as anti-inflammatory and antipruritic agents.

Chemically, fluticasone propionate is C₂₅ H₃₁ F₃ O₅ S.

Fluticasone propionate has a molecular weight of 500.6. It is a white to off-white powder and is insoluble in water.

Each gram of CUTIVATE Cream contains fluticasone propionate 0.5 mg in a base of propylene glycol, mineral oil, cetostearyl alcohol, Ceteth-20, isopropyl myristate, dibasic sodium phosphate, citric acid, purified water, and imidurea as preservative.