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Cuprimine (Penicillamine) - Summary

 

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Physicians planning to use penicillamine should thoroughly familiarize themselves with its toxicity, special dosage considerations, and therapeutic benefits. Penicillamine should never be used casually. Each patient should remain constantly under the close supervision of the physician. Patients should be warned to report promptly any symptoms suggesting toxicity.

 

CUPRIMINE SUMMARY

CUPRIMINE ®
CAPSULES
(PENICILLAMINE)

Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy (see INDICATIONS).

CUPRIMINE is indicated in the treatment of Wilson's disease, cystinuria, and in patients with severe, active rheumatoid arthritis who have failed to respond to an adequate trial of conventional therapy. Available evidence suggests that CUPRIMINE is not of value in ankylosing spondylitis.

CUPRIMINE NEWS HIGHLIGHTS

Published Studies Related to Cuprimine (Penicillamine)

High-dose versus low-dose D-penicillamine in early diffuse systemic sclerosis trial: lessons learned. [2004.02]

The Disability Index of the Health Assessment Questionnaire is a predictor and correlate of outcome in the high-dose versus low-dose penicillamine in systemic sclerosis trial. [2001.03]

D-penicillamine is not an effective treatment in systemic sclerosis. [2001]

Evaluation of antineutrophil cytoplasmic antibody seroconversion induced by minocycline, sulfasalazine, or penicillamine. [2000.11]

Penicillamine in the treatment of systemic sclerosis. [1999.10]

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Clinical Trials Related to Cuprimine (Penicillamine)

Penicillamine Chelation for Children With Lead Poisoning [Active, not recruiting]

Penicillamine, Low Copper Diet, and Radiation Therapy in Treating Patients With Glioblastoma [Active, not recruiting]

more>>

Page last updated: 2006-01-31

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