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Crinone (Progesterone Vaginal) - Summary

 


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CRINONE SUMMARY

Crinone® (progesterone gel) is a bioadhesive vaginal gel containing micronized progesterone in an emulsion system, which is contained in single use, one piece polyethylene vaginal applicators. The carrier vehicle is an oil in water emulsion containing the water swellable, but insoluble polymer, polycarbophil. The progesterone is partially soluble in both the oil and water phase of the vehicle, with the majority of the progesterone existing as a suspension. Physically, Crinone® has the appearance of a soft, white to off-white gel.

Crinone® 8% is indicated for progesterone supplementation or replacement as part of an Assisted Reproductive Technology ("ART") treatment for infertile women with progesterone deficiency.

Crinone® 4% is indicated for the treatment of secondary amenorrhea.

Crinone® 8% is indicated for use in women who have failed to respond to treatment with Crinone® 4%.


See all Crinone indications & dosage >>

CRINONE NEWS HIGHLIGHTS

Media Articles Related to Crinone (Progesterone Vaginal)

Luteal Phase Bleeding Does Not Accurately Predict Ongoing Pregnancy In IVF
Source: Fertility News From Medical News Today [2008.11.17]

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Published Studies Related to Crinone (Progesterone Vaginal)

Progesterone supplementation during cryopreserved embryo transfer cycles: efficacy and convenience of two vaginal formulations. [2008.09]

Comparison of Crinone 8% intravaginal gel and intramuscular progesterone supplementation for in vitro fertilization/embryo transfer in women under age 40: interim analysis of a prospective randomized trial. [2008.02]

Progesterone vaginal gel for the reduction of recurrent preterm birth: primary results from a randomized, double-blind, placebo-controlled trial. [2007.10]

Vaginal progesterone is associated with a decrease in risk for early preterm birth and improved neonatal outcome in women with a short cervix: a secondary analysis from a randomized, double-blind, placebo-controlled trial. [2007.10]

Vaginal progesterone is associated with a decrease in risk for early preterm birth and improved neonatal outcome in women with a short cervix: a secondary analysis from a randomized, double-blind, placebo-controlled trial. [2007.10]

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Clinical Trials Related to Crinone (Progesterone Vaginal)

Multi-Center, Randomized, Open-Label, Parallel Group Study of a Vaginal Micronized Progesterone Tablet (Endometrin®) Compared to Crinone 8% Vaginal Gel in Female Patients Undergoing In-Vitro Fertilization (IVF) [Completed]

Evaluating the Roles of Estrogen and Progesterone in Heart Metabolism [Completed]

Artificial Endometrial Preparation for Frozen Thawed Embryo Transfer Applying Either Endometrin or Utrogestan [Suspended]

Progesterone Reduces Wakefulness in Sleep EEG and Has no Effect on Cognition in Healthy Postmenopausal Women [Completed]

Comparison of Crinone 8% Intravaginal Gel and IM Progesterone Supplementation for In Vitro Fertilization [Recruiting]

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Page last updated: 2008-11-17

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