Coumadin (Warfarin Sodium) - Summary

COUMADIN SUMMARY

COUMADIN (crystalline warfarin sodium) is an anticoagulant which acts by inhibiting vitamin K-dependent coagulation factors.

COUMADIN (Warfarin Sodium) is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, and pulmonary embolism.

COUMADIN is indicated for the prophylaxis and/or treatment of the thromboembolic complications associated with atrial fibrillation and/or cardiac valve replacement.

COUMADIN is indicated to reduce the risk of death, recurrent myocardial infarction, and thromboembolic events such as stroke or systemic embolization after myocardial infarction.

See all Coumadin indications & dosage >>

COUMADIN NEWS HIGHLIGHTS

Media Articles Related to Coumadin (Warfarin)

Joint Aspiration Safety With Coumadin (warfarin)
Source: MedicineNet Joint Aspiration Specialty [2003.01.20]

AHA: Home INR Monitoring for Warfarin Found Safe as Clinic Testing
Source: MedPage Today Neurology [2008.11.13]

Warfarin Underused in Atrial Fibrillation Patients
Source: MedicineNet Atrial Fibrillation Specialty [2008.10.15]

Warfarin Safer Than Heparin for Some Strokes
Source: MedicineNet enoxaparin Specialty [2008.07.15]

Aspirin as effective as warfarin and safer in stroke prevention
Source: The Doctors Lounge - Neurology

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Published Studies Related to Coumadin (Warfarin)

Pharmacodynamic interaction of warfarin with cranberry but not with garlic in healthy subjects. [2008.08]

Aspirin, clopidogrel, and warfarin: is the combination appropriate and effective or inappropriate and too dangerous? [2008.06]

The role of cytochrome P2C19 in R-warfarin pharmacokinetics and its interaction with omeprazole. [2008.06]

Effect of ximelagatran and warfarin on stroke subtypes in atrial fibrillation. [2008.05]

CYP2C9 genotype-guided warfarin prescribing enhances the efficacy and safety of anticoagulation: a prospective randomized controlled study. [2008.03]

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Clinical Trials Related to Coumadin (Warfarin)

Duloxetine - Warfarin Pharmacodynamic Study [Completed]

Access II - Trial of Warfarin to Prevent Malfunction of Haemodialysis Catheters [Completed]

Prospective Genotyping For Total Hip or Knee Replacement Patients Receiving Warfarin (Coumadin) [Recruiting]

Oral Vitamin K for Warfarin Associated Coagulopathy [Active, not recruiting]

A Study Testing the Effect and Safety of Casopitant (GW679769) While Taking Warfarin in Healthy Human Volunteers [Completed]

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COUMADIN PATIENT REVIEWS / RATINGS / COMMENTS

Coumadin review by 61 year old male patient
		Rating
Overall rating:
Effectiveness:		Moderately Effective
Side effects:		Severe Side Effects
		Treatment Info
Condition / reason:		heart murmer
Dosage & duration:		14.5 mg / day taken 1 per day for the period of continually
Other conditions:		none
Other drugs taken:		none
		Reported Results
Benefits:		reduced risk of stroke
Side effects:		excesive bleeding
Comments:		14.5 mg daily

Coumadin review by 59 year old female patient
		Rating
Overall rating:
Effectiveness:		Moderately Effective
Side effects:		Mild Side Effects
		Treatment Info
Condition / reason:		blood clots
Dosage & duration:		2-10 mg taken daily for the period of 8 months
Other conditions:		breast cancer treatment
Other drugs taken:		herceptin
		Reported Results
Benefits:		prevent further clots and to dissolve pulmonary embolism
Side effects:		blood clotting times would vary tremendously and required frequent testing to determine dosage adjustments. Sometimes clotting times would need to be checked weekly or more often.
Comments:		The diet was very restrictive. Too much vitamin K could lead to clots and too little could lead to spontaneous bleeding. Any medical procedure reqiured going off coumadin before hand and going on lovenox shots to the stomach for a week.