Cortisporin®-TC Otic Suspension with Neomycin and Hydrocortisone (colistin sulfate, neomycin sulfate, thonzonium bromide, hydrocortisone acetate otic suspension) is a sterile antibacterial and anti-inflammatory aqueous suspension containing in each mL: Colistin base activity, 3 mg (as the sulfate); Neomycin base activity, 3.3 mg (as the sulfate); Hydrocortisone acetate, 10 mg (1%); Thonzonium bromide, 0.5 mg (0.05%); Polysorbate 80, acetic acid, and sodium acetate in a buffered aqueous vehicle. Thimerosal (mercury derivative), 0.002%, is added as a preservative. It is a nonviscous liquid, buffered at pH 5, for instillation into the canal of the external ear or direct application to the affected aural skin.
Cortisporin®-TC Otic Suspension is indicated for the treatment of superficial bacterial infections of the external auditory canal, caused by organisms susceptible to the action of the antibiotics; and for the treatment of infections of mastoidectomy and fenestration cavities, caused by organisms susceptible to the antibiotics.
Media Articles Related to Cortisporin-TC (Colistin / Neomycin / Thonzonium / Hydrocortisone Otic)
Acute otitis externa: AAO-HNSF updated clinical practice guideline
Source: Ear, Nose and Throat News From Medical News Today [2014.02.05]
With one in every 123 people in the United States affected by Acute Otits Externa or "swimmer's ear" each year, the American Academy of Otolaryngology - Head and Neck Surgery Foundation released an evidence-based guideline to improve the diagnosis and treatment. The guideline, updated from 2006, was published in the journal Otolaryngology - Head and Neck Surgery.