Coreg (Carvedilol) - Summary

COREG SUMMARY

COREG ^® (carvedilol) Tablets

Carvedilol is a nonselective (beta)-adrenergic blocking agent with (alpha)₁-blocking activity. It is (±)-1-(Carbazol-4-yloxy)-3-[[2-(o-methoxyphenoxy)ethyl]amino]-2-propanol. It is a racemic mixture.

Carvedilol is indicated for the following:

Congestive Heart Failure: COREG is indicated for the treatment of mild to severe heart failure of ischemic or cardiomyopathic origin, usually in addition to diuretics, ACE inhibitor, and digitalis, to increase survival and, also, to reduce the risk of hospitalization (see CLINICAL TRIALS).

Left Ventricular Dysfunction Following Myocardial Infarction: COREG is indicated to reduce cardiovascular mortality in clinically stable patients who have survived the acute phase of a myocardial infarction and have a left ventricular ejection fraction of Hypertension: COREG is also indicated for the management of essential hypertension. It can be used alone or in combination with other antihypertensive agents, especially thiazide-type diuretics (see PRECAUTIONS, Drug Interactions).

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COREG NEWS HIGHLIGHTS

Media Articles Related to Coreg (Carvedilol)

FDA OKs 1st Generic Versions of Coreg
Source: MedicineNet carvedilol Specialty [2007.09.06]

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Published Studies Related to Coreg (Carvedilol)

Comparison of the efficacy of metoprolol and carvedilol for preventing atrial fibrillation after coronary bypass surgery. [2008.05.07]

Population pharmacokinetics and dose simulation of carvedilol in paediatric patients with congestive heart failure. [2008.04]

Safety and efficacy of carvedilol therapy for patients with dilated cardiomyopathy secondary to muscular dystrophy. [2008.03]

The impact of carvedilol on the defibrillation threshold. [2008.01]

Comparative dose titration responses to the introduction of bisoprolol or carvedilol in stable chronic systolic heart failure. [2007.12]

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Clinical Trials Related to Coreg (Carvedilol)

A Study to Compare the Effects of Coreg CR and Coreg IR on Heart Function in Subjects With Stable Chronic Heart Failure [Active, not recruiting]

A Study to Compare COREG CR to COREG CR Fixed-Dose Combination in Patients With High Blood Pressure [Completed]

A Study Investigating the Bioequivalence of the Fixed Dose Combination of COREG CR to COREG CR and ZESTRIL. [Completed]

Study to Demonstrate the Bioequivalence of the Fixed Dose Combination of COREG CRâ„¢ and Lisinopril to Its Components [Completed]

Fasting Study of Carvedilol Tablets 12.5 mg to Coreg® Tablets 12.5 mg [Completed]

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COREG PATIENT REVIEWS / RATINGS / COMMENTS

Coreg review by 49 year old female patient
		Rating
Overall rating:
Effectiveness:		Considerably Effective
Side effects:		Moderate Side Effects
		Treatment Info
Condition / reason:		HEART
Dosage & duration:		25MG taken tid for the period of 2 YEARS
Other conditions:		high blood pressure
Other drugs taken:		BP
		Reported Results
Benefits:		HEART WORKS BETTER -NO PVCS- less shortness of breath able to do physical activities again
Side effects:		DRY SKIN wrinkles decreased appetite takes the body a long time to adapt to such a radical change to the heart and lungs
Comments:		took the pill and get checkups? congestive heart failure first confirmed by an echocardiogram wore a holter for 24 hours to detect pvc's