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Coreg CR (Carvedilol Phosphate) - Summary

 

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COREG CR SUMMARY

COREG CR™
(carvedilol phosphate)
Controlled-Release Capsules

Carvedilol phosphate is a nonselective β-adrenergic blocking agent with α1-blocking activity.

COREG CR is indicated for the following:

Heart Failure

COREG CR is indicated for the treatment of mild-to-severe heart failure of ischemic or cardiomyopathic origin, usually in addition to diuretics, ACE inhibitor, and digitalis, to increase survival and, also, to reduce the risk of hospitalization (see CLINICAL TRIALS).

Left Ventricular Dysfunction Following Myocardial Infarction

COREG CR is indicated to reduce cardiovascular mortality in clinically stable patients who have survived the acute phase of a myocardial infarction and have a left ventricular ejection fraction of ≤40% (with or without symptomatic heart failure) (see CLINICAL TRIALS).

Hypertension

COREG CR is indicated for the management of essential hypertension. It can be used alone or in combination with other antihypertensive agents, especially thiazide-type diuretics (see PRECAUTIONS, Drug Interactions).

COREG CR NEWS HIGHLIGHTS

Published Studies Related to Coreg CR (Carvedilol)

Population pharmacokinetics and dose simulation of carvedilol in paediatric patients with congestive heart failure. [2008.04]

Comparison of the effects of carvedilol and metoprolol on exercise ventilatory efficiency in patients with congestive heart failure. [2008.03]

Safety and efficacy of carvedilol therapy for patients with dilated cardiomyopathy secondary to muscular dystrophy. [2008.03]

The impact of carvedilol on the defibrillation threshold. [2008.01]

Comparative dose titration responses to the introduction of bisoprolol or carvedilol in stable chronic systolic heart failure. [2007.12]

more>>

Clinical Trials Related to Coreg CR (Carvedilol)

A Study to Compare COREG CR to COREG CR Fixed-Dose Combination in Patients With High Blood Pressure [Completed]

A Study to Compare the Effects of Coreg CR and Coreg IR on Heart Function in Subjects With Stable Chronic Heart Failure [Active, not recruiting]

Drug Compliance and Quality of Life in Patients With Heart Failure Dosed With Either Once-Daily or Twice-Daily Coreg [Active, not recruiting]

The CLEVER Study - Coreg And Left Ventricular Mass Regression [Active, not recruiting]

Carvedilol Versus Metoprolol for the Prevention of Atrial Fibrillation After Off-Pump Coronary Bypass Surgery [Completed]

more>>

Page last updated: 2008-08-10

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