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Compro (Prochlorperazine Rectal) - Summary

 
 



COMPRO SUMMARY

COMPRO®
PROCHLORPERAZINE SUPPOSITORIES USP, 25mg

Prochlorperazine is a clear, pale yellow, viscous liquid. It is sensitive to light, very slightly soluble in water, freely soluble in alcohol, in chloroform, and in ether. Each suppository, for rectal administration, contains 25 mg of prochlorperazine; with glycerin, glyceryl monopalmitate, glyceryl monostearate, hydrogenated coconut oil fatty acids and hydrogenated palm kernel oil fatty acids.

Prochlorperazine 25mg suppositories are indicated in the control of severe nausea and vomiting in adults.


See all Compro indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Compro (Prochlorperazine Rectal)

Drug allergies reduced without compromising efficacy
Source: Allergy News From Medical News Today [2014.12.07]
An enzyme that usually triggers strong allergic reactions now circulates in the veins of a group of mice without alerting the immune system.

Deficits in one of the brain's off switches for anxiety can result in an anxious temperament
Source: Anxiety / Stress News From Medical News Today [2014.12.04]
Persistent anxiety is one of the most common and distressing symptoms compromising mental health.

The biology of anxious temperament may lie with a problem in an anxiety "off switch"
Source: Anxiety / Stress News From Medical News Today [2014.12.03]
Persistent anxiety is one of the most common and distressing symptoms compromising mental health.

TV sound system for the hard of hearing
Source: Hearing / Deafness News From Medical News Today [2014.11.17]
Families often watch TV together, but what happens when one member has hearing difficulties? Usually the result is a compromise on listening volume that doesn't really satisfy anyone.

Palonosetron and Aprepitant for Postop Nausea and Vomiting
Source: Medscape Anesthesiology Headlines [2014.12.08]
This study compares palonosetron with aprepitant for the prevention of postop nausea and vomiting.
BMC Anesthesiology

more news >>

Published Studies Related to Compro (Prochlorperazine Rectal)

Indomethacin/prochlorperazine/caffeine: a review of its use in the acute treatment of migraine and in the treatment of episodic tension-type headache. [2011.04.01]
The indomethacin/prochlorperazine/caffeine fixed combination (Difmetre(R)) combines the NSAID indomethacin with the phenothiazine antiemetic prochlorperazine and caffeine. It is currently available as two oral (effervescent tablet and coated tablet) and two rectal (suppository and low-dose suppository) formulations...

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Clinical Trials Related to Compro (Prochlorperazine Rectal)

StaccatoŽ Prochlorperazine for Inhalation [Completed]

Staccato Prochlorperazine in Patients With Migraine Headache [Completed]

Prochlorperazine vs Imitrex for Acute Migraine in the Emergency Department [Completed]
ED patients with acute migraine will be randomized to either prochlorperazine and Bendaryl OR imitrex. VAS for pain will be monitored, along with side effects. Primary outcome measure is improvement in pain scales between the groups.

Ondansetron vs Prochlorperazine for Nausea and Vomiting in the Emergency Department [Recruiting]
This study will compare the effect of prochlorperazine and ondansetron for the treatment of nausea and vomiting in the emergency department.

StaccatoŽ Prochlorperazine for Inhalation in Migraine [Completed]
Staccato Prochlorperazine is being developed to treat patients suffering from acute migraine headaches. In October 2005, we completed a 75 patient, multi-center, double-blind placebo-controlled Phase 2A clinical trial in patients suffering from moderate to severe acute migraine headaches. This Phase 2B clinical trial of Staccato Prochlorperazine has been initiated to assess the efficacy and safety in outpatients with migraine headache with or without aura.

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Page last updated: 2014-12-08

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