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Compro (Prochlorperazine Rectal) - Summary

 
 



COMPRO SUMMARY

COMPRO®
PROCHLORPERAZINE SUPPOSITORIES USP, 25mg

Prochlorperazine is a clear, pale yellow, viscous liquid. It is sensitive to light, very slightly soluble in water, freely soluble in alcohol, in chloroform, and in ether. Each suppository, for rectal administration, contains 25 mg of prochlorperazine; with glycerin, glyceryl monopalmitate, glyceryl monostearate, hydrogenated coconut oil fatty acids and hydrogenated palm kernel oil fatty acids.

Prochlorperazine 25mg suppositories are indicated in the control of severe nausea and vomiting in adults.


See all Compro indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Compro (Prochlorperazine Rectal)

Study compares consequences of teen alcohol and marijuana use
Source: Alcohol / Addiction / Illegal Drugs News From Medical News Today [2014.09.03]
The study found that for high school seniors, alcohol consumption led to unsafe driving and compromised relationships with peers, while marijuana consumption was found to compromise relationships...

Research has implications for understanding brain diseases caused by clumps of misshapen molecules
Source: Muscular Dystrophy / ALS News From Medical News Today [2014.06.02]
It's almost axiomatic that misfolded proteins compromise how cells normally function and cause debilitating human disease, but how these proteins are detected and degraded within the body is not well...

Nausea and Vomiting
Source: MedicineNet Anaphylaxis Specialty [2014.07.09]
Title: Nausea and Vomiting
Category: Diseases and Conditions
Created: 1/31/2005 8:21:00 AM
Last Editorial Review: 7/9/2014 12:00:00 AM

more news >>

Published Studies Related to Compro (Prochlorperazine Rectal)

Indomethacin/prochlorperazine/caffeine: a review of its use in the acute treatment of migraine and in the treatment of episodic tension-type headache. [2011.04.01]
The indomethacin/prochlorperazine/caffeine fixed combination (Difmetre(R)) combines the NSAID indomethacin with the phenothiazine antiemetic prochlorperazine and caffeine. It is currently available as two oral (effervescent tablet and coated tablet) and two rectal (suppository and low-dose suppository) formulations...

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Clinical Trials Related to Compro (Prochlorperazine Rectal)

StaccatoŽ Prochlorperazine for Inhalation [Completed]

Staccato Prochlorperazine in Patients With Migraine Headache [Completed]

Prochlorperazine vs Imitrex for Acute Migraine in the Emergency Department [Completed]
ED patients with acute migraine will be randomized to either prochlorperazine and Bendaryl OR imitrex. VAS for pain will be monitored, along with side effects. Primary outcome measure is improvement in pain scales between the groups.

Ondansetron vs Prochlorperazine for Nausea and Vomiting in the Emergency Department [Recruiting]
This study will compare the effect of prochlorperazine and ondansetron for the treatment of nausea and vomiting in the emergency department.

StaccatoŽ Prochlorperazine for Inhalation in Migraine [Completed]
Staccato Prochlorperazine is being developed to treat patients suffering from acute migraine headaches. In October 2005, we completed a 75 patient, multi-center, double-blind placebo-controlled Phase 2A clinical trial in patients suffering from moderate to severe acute migraine headaches. This Phase 2B clinical trial of Staccato Prochlorperazine has been initiated to assess the efficacy and safety in outpatients with migraine headache with or without aura.

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Page last updated: 2014-09-03

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