PROCHLORPERAZINE SUPPOSITORIES USP, 25mg
Prochlorperazine is a clear, pale yellow, viscous liquid. It is sensitive to light, very slightly soluble in water, freely soluble in alcohol, in chloroform, and in ether. Each suppository, for rectal administration, contains 25 mg of prochlorperazine; with glycerin, glyceryl monopalmitate, glyceryl monostearate, hydrogenated coconut oil fatty acids and hydrogenated palm kernel oil fatty acids.
Prochlorperazine 25mg suppositories are indicated in the control of severe nausea and vomiting in adults.
Media Articles Related to Compro (Prochlorperazine Rectal)
Drinking water downstream from 'fracking' sites may be compromised
Source: Public Health News From Medical News Today [2014.09.26]
Concerns that fluids from hydraulic fracturing, or "fracking," are contaminating drinking water abound. Now, scientists are bringing to light another angle that adds to the controversy.
How pneumonia bacteria can compromise heart health
Source: Respiratory / Asthma News From Medical News Today [2014.09.18]
Bacterial pneumonia in adults carries an elevated risk for adverse cardiac events (such as heart failure, arrhythmias, and heart attacks) that contribute substantially to mortality - but how the...
Rolapitant Reduces Chemo-Induced Nausea and Vomiting
Source: Medscape Medical News Headlines [2014.09.27]
An investigational NK-1 receptor antagonist as demonstrated a significant effect in both acute and delayed phases.
Medscape Medical News
Nausea and Vomiting
Source: MedicineNet Anaphylaxis Specialty [2014.07.09]
Title: Nausea and Vomiting
Category: Diseases and Conditions
Created: 1/31/2005 8:21:00 AM
Last Editorial Review: 7/9/2014 12:00:00 AM
Published Studies Related to Compro (Prochlorperazine Rectal)
Indomethacin/prochlorperazine/caffeine: a review of its use in the acute treatment of migraine and in the treatment of episodic tension-type headache. [2011.04.01]
The indomethacin/prochlorperazine/caffeine fixed combination (Difmetre(R)) combines the NSAID indomethacin with the phenothiazine antiemetic prochlorperazine and caffeine. It is currently available as two oral (effervescent tablet and coated tablet) and two rectal (suppository and low-dose suppository) formulations...
Clinical Trials Related to Compro (Prochlorperazine Rectal)
StaccatoŽ Prochlorperazine for Inhalation [Completed]
Staccato Prochlorperazine in Patients With Migraine Headache [Completed]
Prochlorperazine vs Imitrex for Acute Migraine in the Emergency Department [Completed]
ED patients with acute migraine will be randomized to either prochlorperazine and Bendaryl OR
imitrex. VAS for pain will be monitored, along with side effects. Primary outcome measure is
improvement in pain scales between the groups.
Ondansetron vs Prochlorperazine for Nausea and Vomiting in the Emergency Department [Recruiting]
This study will compare the effect of prochlorperazine and ondansetron for the treatment of
nausea and vomiting in the emergency department.
StaccatoŽ Prochlorperazine for Inhalation in Migraine [Completed]
Staccato Prochlorperazine is being developed to treat patients suffering from acute migraine
headaches. In October 2005, we completed a 75 patient, multi-center, double-blind
placebo-controlled Phase 2A clinical trial in patients suffering from moderate to severe
acute migraine headaches. This Phase 2B clinical trial of Staccato Prochlorperazine has been
initiated to assess the efficacy and safety in outpatients with migraine headache with or