Compro (Prochlorperazine Rectal) - Summary

COMPRO SUMMARY

COMPRO^®
PROCHLORPERAZINE SUPPOSITORIES USP, 25mg

Prochlorperazine is a clear, pale yellow, viscous liquid. It is sensitive to light, very slightly soluble in water, freely soluble in alcohol, in chloroform, and in ether. Each suppository, for rectal administration, contains 25 mg of prochlorperazine; with glycerin, glyceryl monopalmitate, glyceryl monostearate, hydrogenated coconut oil fatty acids and hydrogenated palm kernel oil fatty acids.

Prochlorperazine 25mg suppositories are indicated in the control of severe nausea and vomiting in adults.

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NEWS HIGHLIGHTS

Media Articles Related to Compro (Prochlorperazine Rectal)

Childhood Stress Compromises Immune System
Source: MedicineNet Herpes Simplex Infections (Non-Genital) Specialty [2009.01.29]
Title: Childhood Stress Compromises Immune System
Category: Health News
Created: 1/29/2009 2:00:00 AM
Last Editorial Review: 1/29/2009

A Selection Of Today's Opinions And Editorials
Source: Health News from Medical News Today [2009.11.19]
What Our Amendment Does Politico Rather than work with us to find a true compromise, members who support abortion rights ignored our concerns (Rep. Bart Stupak, D-Mich., 11/18). Health 'Reform' Gets a Failing Grade The Wall Street Journal As the dean of Harvard Medical School I am frequently asked to comment on the health-reform debate. I'd give it a failing grade (Jeffrey S.

New Research Shows Over-use Of Asthma Rescue Inhalers Substantially Reduced Through Pharmacist-initiated Physician Intervention
Source: Respiratory / Asthma News From Medical News Today [2009.11.13]
Research presented at the American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting shows that an intervention to reduce over-dispensing and waste of asthma medications can succeed without compromising patient safety and can result in substantial cost savings. Medco Health Solutions, Inc.

Resident Duty-Hour Cuts Said to Impair Surgical Education, Safety (CME/CE)
Source: MedPage Today Surgery [2009.11.05]
Limiting surgical residents' work hours has compromised both surgical education and patient safety, according to an analysis concluding that the 80-hour work week in the U.S. isn't enough.

Daily X-Rays Not Needed for Ventilated Patients (CME/CE, with audio)
Source: MedPage Today Radiology [2009.11.04]
Chest radiographs for mechanically ventilated patients that are taken as needed, rather than as part of daily routine, reduce radiation exposure without compromising safety, researchers found.

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Clinical Trials Related to Compro (Prochlorperazine Rectal)

Staccato® Prochlorperazine for Inhalation [Completed]

Staccato Prochlorperazine in Patients With Migraine Headache [Completed]

Prochlorperazine vs Imitrex for Acute Migraine in the Emergency Department [Completed]
ED patients with acute migraine will be randomized to either prochlorperazine and Bendaryl OR imitrex. VAS for pain will be monitored, along with side effects. Primary outcome measure is improvement in pain scales between the groups.

Staccato® Prochlorperazine for Inhalation in Migraine [Completed]
Staccato Prochlorperazine is being developed to treat patients suffering from acute migraine headaches. In October 2005, we completed a 75 patient, multi-center, double-blind placebo-controlled Phase 2A clinical trial in patients suffering from moderate to severe acute migraine headaches. This Phase 2B clinical trial of Staccato Prochlorperazine has been initiated to assess the efficacy and safety in outpatients with migraine headache with or without aura.

Staccato Prochlorperazine Thorough QT/QTc Study [Completed]

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