COLYTE SUMMARY
colyte® with flavor packs is a colon lavage preparation provided as water-soluble components for solution. In solution this preparation with one flavor pack added delivers the following, in grams per liter.
colyte® with flavor packs is indicated for bowel cleansing prior to colonoscopy or barium enema X-ray examination.
PEDIATRIC USE
Safety and effectiveness in pediatric patients have not been established.
GERIATRIC USE
Published literature contains isolated reports of serious adverse reactions following the administration of PEG-ELS products in patients over 60 years of age. These adverse events include upper GI bleeding from Mallory-Weiss Tear, esophageal perforation, asystole, sudden dyspnea with pulmonary edema, and "butterfly-like" infiltrate on chest x-ray after vomiting and aspirating PEG.
|
NEWS HIGHLIGHTS
Published Studies Related to Colyte (Polyethylene Glycol 3350)
Reduced cathartic bowel preparation for CT colonography: prospective comparison of 2-L polyethylene glycol and magnesium citrate. [2011.10]
PURPOSE: To prospectively compare adequacy of colonic cleansing, adequacy of solid stool and fluid tagging, and patient acceptance by using reduced-volume, 2-L polyethylene glycol (PEG) versus magnesium citrate bowel preparations for CT colonography... CONCLUSION: Reduced-volume PEG and magnesium citrate bowel preparations demonstrated adequate cleansing effectiveness for CT colonography, with better tagging and shorter interpretation time observed in the PEG group. Adequate polyp detection was maintained but requires further validation because of the small number of clinically important polyps. (c) RSNA, 2011.
Effect of bowel preparation with polyethylene glycol on quality of capsule endoscopy. [2011.06]
BACKGROUND AND AIMS: Capsule endoscopy (CE) has the problem that lumen visualization is impaired by bubbles, bile, and debris. The benefits of bowel preparation are still controversial and the best method remains to be determined. The objective of this study was to evaluate the effect of the method of bowel preparation on the quality of visualization and on transit time... CONCLUSIONS: Bowel preparation with PEG resulted in better image quality than fasting alone. No significant difference was observed between 2 and 4 l. PEG 2 l rather than 4 l may be a useful method of preparation for CE.
Low-volume bowel preparation is inferior to standard 4 1 polyethylene glycol. [2011.03]
BACKGROUND: Four liters or more of orally taken polyethylene glycol solution (PEG) has proved to be an effective large-bowel cleansing method prior to colonoscopy. The problem has been the large volume of fluid and its taste, which is unacceptable to some examinees. We aimed to investigate the effectiveness of 2 l PEG combined with senna compared with 4 l PEG for bowel preparation... CONCLUSIONS: 4 l PEG treatment is better than 36 mg senna and 2 l PEG as routine colonic cleansing before colonoscopy because of fewer failures.
Comparison of the effectiveness of polyethylene glycol 4000 without electrolytes and magnesium hydroxide in the treatment of chronic functional constipation in children. [2011.01]
OBJECTIVE: To compare the effectiveness of two drugs, polyethylene glycol 4000 without electrolytes and magnesium hydroxide, in the treatment of chronic functional constipation in children... CONCLUSION: The two laxatives showed no difference in effectiveness for the treatment of constipation. However, due to its better acceptance, because it is odorless and tasteless, polyethylene glycol proved to be a better option for treating chronic functional constipation.
The effects of polyethylene glycosylated creatine supplementation on muscular strength and power. [2010.12]
The purpose of the present investigation was to examine the effects of 28 days of polyethylene glycosylated creatine (PEG-creatine) supplementation on 1-repetition maximum bench press (1RMBP) and leg extension (1RMLE), mean power (MP), and peak power (PP) from the Wingate Anaerobic test and body weight (BW)...
Clinical Trials Related to Colyte (Polyethylene Glycol 3350)
Comparing 4L Golytely to 2L Golytely With 15mg Bisacodyl Regimens for Inpatient Colonic Preparation [Recruiting]
The investigators wish to compare the efficacy and patient tolerability of a preparation
consisting of 2L Golytely (PEG + electrolytes) plus 15mg of bisacodyl vs the standard
preparation of 4L Golytely. The investigators hypothesize that 2L Golytely with 15mg
bisacodyl will show similar bowel cleansing efficacy while offering better tolerability.
A Trial Comparing Bowel Preparation and Patient Tolerability of Miralax Versus Golytely [Not yet recruiting]
Prior to colonoscopies, the colon is cleansed using a laxative. Golytely is approved by the
FDA for this purpose. Another laxative, called MiraLax, is approved by the FDA to relieve
constipation, but it is not approved specifically for preparation for a colonoscopy.
Nonetheless, it is commonly used in clinical practice for this purpose, just as is Golytely.
The purpose of this study is to compare Golytely and MiraLax in two ways: to see whether one
is better tolerated by patients than the other and to see whether one more effectively
cleanses the bowel than the other. The investigators' hypothesis is that these 2 bowel
preparation methods are equally effective in bowel cleansing, but that patients prefer
Miralax to Golytely.
Amitiza® Plus GoLYTELY® Versus Placebo Plus GoLYTELY® for Outpatient Colonoscopy Preparation [Recruiting]
The primary objective is to compare the effectiveness and tolerance of Amitiza®
(lubiprostone) plus GoLYTELY® (polyethylene glycol-electrolyte solution) versus placebo and
GoLYTELY ® (polyethylene glycol-electrolyte solution) as a bowel cleansing preparation for
colonoscopy.
Study of Efficacy and Tolerability of Various Bowel Preps in Diabetic Patients [Recruiting]
Poor bowel preparation and patient intolerance of the procedure are the most important
factors contributing to the limitation of colonoscopy. Inadequate bowel cleansing results in
incomplete testing, increased potential to miss lesions, increased cost, and decreased
patient satisfaction. The investigators hope to gain better insight into which bowel
preparation works best in diabetic patients and hence would increase patient satisfaction,
tolerability of the bowel preparation and decrease overall costs. The investigators will
investigate which bowel preparation for colonoscopy will work optimally in diabetic patients
using three different regimens.
A Study Comparing PEG-3350 (Miralax) and Gatorade With PEG-ELS (Golytely) for Bowel Preparation Prior to Colonoscopy [Recruiting]
The purpose of this study to to see how well Miralax (PEG-3350) and Gatorade cleans the
colon before a colonoscopy and how easy it is to take compared to Golytely (PEG-ELS) bowel
preparation solution. Another purpose is to see if taking half of the bowel preparation
solution on the evening before the colonoscopy and half on the morning of the colonoscopy
will result in a cleaner colon than taking all of the bowel preparation solution on the
evening before.
|
