Cogentin (Benztropine Mesylate) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

The adverse reactions below, most of which are anticholinergic in nature, have been reported and within each category are listed in order of decreasing severity.

Cardiovascular

Tachycardia.

Digestive

Paralytic ileus, constipation, vomiting, nausea, dry mouth.

If dry mouth is so severe that there is difficulty in swallowing or speaking, or loss of appetite and weight, reduce dosage, or discontinue the drug temporarily.

Slight reduction in dosage may control nausea and still give sufficient relief of symptoms. Vomiting may be controlled by temporary discontinuation, followed by resumption at a lower dosage.

Nervous System

Toxic psychosis, including confusion, disorientation, memory impairment, visual hallucinations; exacerbation of pre-existing psychotic symptoms; nervousness; depression; listlessness; numbness of fingers.

Special Senses

Blurred vision, dilated pupils.

Urogenital

Urinary retention, dysuria.

Metabolic/Immune or Skin

Occasionally, an allergic reaction, e.g., skin rash, develops. If this cannot be controlled by dosage reduction, the medication should be discontinued.

Other

Heat stroke, hyperthermia, fever.

REPORTS OF SIDE EFFECTS / ADVERSE REACTIONS RELATED TO COGENTIN

Possible Cogentin side effects / adverse reactions in 48 year old male

Reported by a physician from United States on 2007-02-20

Patient: 48 year old male

Reactions: RED Cell Distribution Width Increased, Thrombocythaemia

Suspect drug(s):
Cogentin
    Indication: Drug USE FOR Unknown Indication

Risperidone
    Dosage: q2w; im
    Indication: Drug USE FOR Unknown Indication

Depakote
    Indication: Drug USE FOR Unknown Indication

Possible Cogentin side effects / adverse reactions in 27 year old female

Reported by a individual with unspecified qualification from United States on 2007-03-20

Patient: 27 year old female weighing 77.1 kg (169.6 pounds)

Reactions: Weight Increased, Stomatitis, Visual Disturbance, Tardive Dyskinesia

Suspect drug(s):
Risperdal
    Dosage: 25-55 millagrams ever 2 weeks iv
    Indication: Schizophrenia
    Start date: 2006-07-01
    End date: 2007-01-31

Cogentin
    Dosage: 3 a day 3 a day po
    Administration route: Oral
    Indication: Restlessness
    Start date: 2006-07-01
    End date: 2006-09-01

Possible Cogentin side effects / adverse reactions in 95 year old female

Reported by a pharmacist from United States on 2007-05-30

Patient: 95 year old female weighing 56.9 kg (125.2 pounds)

Reactions: Confusional State, Speech Disorder, Dystonia, Agonal Death Struggle, Motor Dysfunction, Chest Pain, Respiratory Arrest, Extrapyramidal Disorder, Respiratory Distress, Muscle Spasms

Adverse event resulted in: death, hospitalization

Suspect drug(s):
Ranexa
    Dosage: 1000 mg bid po
    Administration route: Oral
    Indication: Angina Pectoris
    Start date: 2007-05-25
    End date: 2007-05-28

Ranexa
    Dosage: 1000 mg bid po
    Administration route: Oral
    Indication: Coronary Artery Disease
    Start date: 2007-05-25
    End date: 2007-05-28

Cogentin
    Dosage: 1 mg once iv
    Indication: Extrapyramidal Disorder
    Start date: 2007-05-29
    End date: 2007-05-29