Cogentin (Benztropine Mesylate) - Summary

COGENTIN SUMMARY

COGENTIN^®
(Benztropine Mesylate Injection)

Benztropine mesylate is a synthetic compound containing structural features found in atropine and diphenhydramine.

COGENTIN (benztropine) is indicated for the following:

For use as an adjunct in the therapy of all forms of parkinsonism.

Useful also in the control of extrapyramidal disorders (except tardive dyskinesia — see PRECAUTIONS) due to neuroleptic drugs (e.g., phenothiazines).

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COGENTIN NEWS HIGHLIGHTS

Published Studies Related to Cogentin (Benztropine)

Formulation and biopharmaceutical evaluation of transdermal patch containing benztropine. [2008.06.05]

Dopamine transport inhibitors based on GBR12909 and benztropine as potential medications to treat cocaine addiction. [2008.01.01]

Fatal exertional heat stroke in a patient receiving zuclopenthixol, quetiapine and benztropine. [2007.09]

Transport, metabolism, and in vivo population pharmacokinetics of the chloro benztropine analogs, a class of compounds extensively evaluated in animal models of drug abuse. [2007.01]

Benztropine pretreatment does not affect responses to acute cocaine administration in human volunteers. [2006.12]

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Clinical Trials Related to Cogentin (Benztropine)

Evaluation of Benztropine for Cocaine Craving - 2 [Completed]

Anticholinergic Burden in Schizophrenia [Recruiting]

A Phase II/III Double-Blind Study of Amitriptyline and Mexiletine for Painful Neuropathy in HIV Infection [Completed]

Effect of Antidepressants on Back Pain [Completed]

A Comparison Study of the Efficacy of Quetiapine and Haloperidol in Agitated Adults in Emergency Room [Recruiting]

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