Codeine Related Published Studies
Well-designed clinical trials related to Codeine
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction. [2011.07]
Analgesia with paracetamol/tramadol vs. paracetamol/codeine in one day-surgery: a randomized open study. [2011.02]
Influence of codeine on lobeline-induced respiratory reflexes and sensations and on ventilation with exercise in healthy subjects. [2011.01.31]
The effects of methylnaltrexone alone and in combination with acutely administered codeine on gastrointestinal and colonic transit in health. [2010.10]
Differential effect of codeine on thermal nociceptive sensitivity in sleepy versus nonsleepy healthy subjects. [2010.06]
Paracetamol (acetaminophen) with or without an antiemetic for acute migraine
headaches in adults. [2010]
Efficacy of oxycodone/acetaminophen and codeine/acetaminophen vs. conventional therapy in elderly women with persistent, moderate to severe osteoarthritis-related pain. [2009.11]
Comparison of ibuprofen and acetaminophen with codeine following cosmetic facial surgery. [2009.10]
A randomized clinical trial of ibuprofen versus acetaminophen with codeine for acute pediatric arm fracture pain. [2009.10]
Ibuprofen provides analgesia equivalent to acetaminophen-codeine in the treatment of acute pain in children with extremity injuries: a randomized clinical trial. [2009.08]
O-demethylation of codeine to morphine inhibited by low-dose levomepromazine. [2009.08]
The Leeds Evaluation of Efficacy of Detoxification Study (LEEDS) prisons project: a randomised controlled trial comparing dihydrocodeine and buprenorphine for opiate detoxification. [2009.02.05]
Oxycodone versus codeine for triage pain in children with suspected forearm fracture: a randomized controlled trial. [2008.09]
A randomized controlled trial comparing acetaminophen plus ibuprofen versus acetaminophen plus codeine plus caffeine after outpatient general surgery. [2008.03]
Comparison of analgesic effects and patient tolerability of nabilone and dihydrocodeine for chronic neuropathic pain: randomised, crossover, double blind study. [2008.01.26]
Comparison of perceived itch induced by skin prick-tests with histamine and codeine. [2008]
Pharmacokinetic-pharmacodynamic modeling of the miotic effects of dihydrocodeine in humans. [2007.11]
Comparison of codeine phosphate and morphine sulphate in infants undergoing cleft palate repair. [2007.09]
Comparison of the analgesic efficacy and respiratory effects of morphine, tramadol and codeine after craniotomy. [2007.06]
Codeine/acetaminophen and hydrocodone/acetaminophen combination tablets for the management of chronic cancer pain in adults: a 23-day, prospective, double-blind, randomized, parallel-group study. [2007.04]
A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma. [2007.03]
Buprenorphine versus dihydrocodeine for opiate detoxification in primary care: a randomised controlled trial. [2007.01.08]
The effect of codeine on the Urge-to-Cough response to inhaled capsaicin. [2007]
Well-designed clinical trials possibly related to Codeine
Pregabalin and gabapentin for post-photorefractive keratectomy pain: a randomized
controlled trial. [2012]
Tolerability and efficacy of two synergistic ratios of oral morphine and
oxycodone combinations versus morphine in patients with chronic noncancer pain. [2012]
Addition of pregabalin to multimodal analgesic therapy following ankle surgery: a
randomized double-blind, placebo-controlled trial. [2012]
Liver cancer: effects, safety, and cost-effectiveness of controlled-release
oxycodone for pain control after TACE. [2012]
Sensitivity of gait parameters to the effects of anti-inflammatory and opioid
treatments in knee osteoarthritis patients. [2012]
A randomized, double-blind, active-controlled, double-dummy, parallel-group study
to determine the safety and efficacy of oxycodone/naloxone prolonged-release
tablets in patients with moderate/severe, chronic cancer pain. [2012]
Effect of tapentadol extended release on productivity: results from an analysis
combining evidence from multiple sources. [2012]
Buprenorphine 5, 10 and 20 mug/h Transdermal Patch: A Review of its Use in the Management of Chronic Non-Malignant Pain. [2011.12.24]
A randomised controlled trial of two analgesic techniques for paediatric tonsillectomy*. [2011.10]
Oxycodone lengthens reproductions of suprasecond time intervals in human research volunteers. [2011.08]
Clinical outcomes during opioid titration following initiation with or conversion to Remoxy(R), an extended-release formulation of oxycodone. [2011.07]
Inhibition of cytochrome P450 3A by clarithromycin uniformly affects the pharmacokinetics and pharmacodynamics of oxycodone in young and elderly volunteers. [2011.06]
Oral oxycodone offers equivalent analgesia to intravenous patient-controlled analgesia after total hip replacement: a randomized, single-centre, non-blinded, non-inferiority study. [2011.06]
Pregabalin has an opioid-sparing effect in elderly patients after cardiac surgery: a randomized placebo-controlled trial. [2011.06]
Analgesic and adverse effects of a fixed-ratio morphine-oxycodone combination (MoxDuo) in the treatment of postoperative pain. [2011.05]
Efficacy and safety of an extended-release oxycodone (Remoxy) formulation in patients with moderate to severe osteoarthritic pain. [2011.05]
Positive and negative subjective effects of extended-release oxymorphone versus controlled-release oxycodone in recreational opioid users. [2011.05]
Efficacy of augmenting a subacromial continuous-infusion pump with a preoperative interscalene block in outpatient arthroscopic shoulder surgery: a prospective, randomized, blinded, and placebo-controlled study. [2011.05]
Comparable efficacy and superior gastrointestinal tolerability (nausea, vomiting, constipation) of tapentadol compared with oxycodone hydrochloride. [2011.05]
Randomized controlled trial of percutaneous vertebroplasty versus optimal medical management for the relief of pain and disability in acute osteoporotic vertebral compression fractures. [2011.05]
Nicotine nasal spray as an adjuvant analgesic for third molar surgery. [2011.05]
The use of a non-benzodiazepine hypnotic sleep-aid (Zolpidem) in patients undergoing ACL reconstruction: a randomized controlled clinical trial. [2011.05]
The abuse potential of Remoxy((R)), an extended-release formulation of oxycodone, compared with immediate- and extended-release oxycodone. [2011.04]
Psychopharmacological effects of oxycodone in volunteers with and without generalized anxiety disorder. [2011.04]
Naloxone as part of a prolonged release oxycodone/naloxone combination reduces oxycodone-induced slowing of gastrointestinal transit in healthy volunteers. [2011.04]
The efficacy and safety of fentanyl buccal tablet compared with immediate-release oxycodone for the management of breakthrough pain in opioid-tolerant patients with chronic pain. [2011.03]
A randomised, five-parallel-group, placebo-controlled trial comparing the efficacy and tolerability of analgesic combinations including a novel single-tablet combination of ibuprofen/paracetamol for postoperative dental pain. [2011.03]
Efficacy and safety of oxycodone HCl/niacin tablets for the treatment of moderate-to-severe postoperative pain following bunionectomy surgery. [2011.03]
Miconazole oral gel increases exposure to oral oxycodone by inhibition of CYP2D6 and CYP3A4. [2011.03]
Pain management in young children undergoing diagnostic tympanocentesis. [2011.03]
Oral gabapentin for photorefractive keratectomy pain. [2011.02]
Effect of high-dose preoperative methylprednisolone on pain and recovery after total knee arthroplasty: a randomized, placebo-controlled trial. [2011.02]
Intra-articular morphine enhances analgesic efficacy of ropivacaine for knee arthroscopy in ambulatory patients. [2011.01.01]
A randomized comparison of infraclavicular and supraclavicular continuous peripheral nerve blocks for postoperative analgesia. [2011.01]
Evaluation of the dose range of etoricoxib in an acute pain setting using the postoperative dental pain model. [2011.01]
The subjective, reinforcing, and analgesic effects of oxycodone in patients with chronic, non-malignant pain who are maintained on sublingual buprenorphine/naloxone. [2011.01]
Effect of the inhibition of CYP3A4 or CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone. [2011.01]
Effect of inhibition of cytochrome P450 enzymes 2D6 and 3A4 on the pharmacokinetics of intravenous oxycodone: a randomized, three-phase, crossover, placebo-controlled study. [2011]
Post hoc analyses of data from a 90-day clinical trial evaluating the
tolerability and efficacy of tapentadol immediate release and oxycodone immediate
release for the relief of moderate to severe pain in elderly and nonelderly
patients. [2011]
Analgesic and adverse effects of a fixed-ratio morphine-oxycodone combination
(MoxDuo) in the treatment of postoperative pain. [2011]
Efficacy and safety of an extended-release oxycodone (Remoxy) formulation in
patients with moderate to severe osteoarthritic pain. [2011]
Efficacy and safety of buprenorphine transdermal system (BTDS) for chronic
moderate to severe low back pain: a randomized, double-blind study. [2011]
Short-term opioids for breathlessness in stable chronic heart failure: a
randomized controlled trial. [2011]
Efficacy of augmenting a subacromial continuous-infusion pump with a preoperative
interscalene block in outpatient arthroscopic shoulder surgery: a prospective,
randomized, blinded, and placebo-controlled study. [2011]
Oral gabapentin for photorefractive keratectomy pain. [2011]
A pharmacokinetic and pharmacodynamic study of oral oxycodone in a human experimental pain model of hyperalgesia. [2010.12.01]
Superficial cervical plexus block for transitional analgesia in infratentorial and occipital craniotomy: a randomized trial. [2010.12]
Hydroxyurea and acute painful crises in sickle cell anemia: effects on hospital length of stay and opioid utilization during hospitalization, outpatient acute care contacts, and at home. [2010.12]
Reduced cognitive and psychomotor impairment with extended-release oxymorphone versus controlled-release oxycodone. [2010.11]
Morphine versus oxycodone in pancreatic cancer pain: a randomized controlled study. [2010.11]
A comparison of the respiratory effects of oxycodone versus morphine: a randomised, double-blind, placebo-controlled investigation. [2010.10]
Oxycodone concentrations are greatly increased by the concomitant use of ritonavir or lopinavir/ritonavir. [2010.10]
Intravenous oxycodone, hydrocodone, and morphine in recreational opioid users: abuse potential and relative potencies. [2010.10]
Predicting the analgesic effect to oxycodone by 'static' and 'dynamic' quantitative sensory testing in healthy subjects. [2010.10]
Grapefruit juice enhances the exposure to oral oxycodone. [2010.10]
Efficacy and safety of combined prolonged-release oxycodone and naloxone in the management of moderate/severe chronic non-malignant pain: results of a prospectively designed pooled analysis of two randomised, double-blind clinical trials. [2010.09.29]
Superficial cervical plexus block for transitional analgesia in infratentorial and occipital craniotomy: a randomized trial. [2010.09.28]
Hydroxyurea and Acute Painful Crises in Sickle Cell Anemia: Effects on Hospital Length of Stay and Opioid Utilization During Hospitalization, Outpatient Acute Care Contacts, and at Home. [2010.09.21]
A double-blind, placebo-controlled study of dual-opioid treatment with the combination of morphine plus oxycodone in patients with acute postoperative pain. [2010.09]
Dilute proparacaine for the management of acute corneal injuries in the emergency department. [2010.09]
A randomized study to demonstrate noninferiority of once-daily OROS((R)) hydromorphone with twice-daily sustained-release oxycodone for moderate to severe chronic noncancer pain. [2010.09]
St John's wort greatly reduces the concentrations of oral oxycodone. [2010.09]
Different effects of morphine and oxycodone in experimentally evoked hyperalgesia: a human translational study. [2010.08]
Effects of pain management on sleep in preterm infants. [2010.08]
The antinociceptive effect and adverse drug reactions of oxycodone in human experimental pain in relation to genetic variations in the OPRM1 and ABCB1 genes. [2010.08]
Human abuse liability assessment of oxycodone combined with ultra-low-dose naltrexone. [2010.07]
Exposure to oral oxycodone is increased by concomitant inhibition of CYP2D6 and 3A4 pathways, but not by inhibition of CYP2D6 alone. [2010.07]
Evaluation of efficacy of the perioperative administration of Venlafaxine or gabapentin on acute and chronic postmastectomy pain. [2010.06]
The influence of ondansetron on the analgesic effect of acetaminophen after laparoscopic hysterectomy. [2010.06]
Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety. [2010.06]
Evaluation of study discontinuations with tapentadol inmmediate release and oxycodone immediate release in patients with low back or osteoarthritis pain. [2010.05]
Buprenorphine transdermal system for opioid therapy in patients with chronic low back pain. [2010.05]
A randomized, controlled trial of oxycodone versus placebo in patients with postherpetic neuralgia and painful diabetic neuropathy treated with pregabalin. [2010.05]
Magnesium and headache after aneurysmal subarachnoid haemorrhage. [2010.05]
Adjunctive tamsulosin improves stone free rate after ureteroscopic lithotripsy of large renal and ureteric calculi: a prospective randomized study. [2010.05]
Long-term efficacy and safety of combined prolonged-release oxycodone and naloxone in the management of non-cancer chronic pain. [2010.05]
Brief report: improved pain relief using intermittent bupivacaine injections at the donor site after breast reconstruction with deep inferior epigastric perforator flap. [2010.04.01]
A prospective, single-blind randomised study on the effect of intercostal nerve protection on early post-thoracotomy pain relief. [2010.04]
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