Clotrimazole (Clotrimazole Topical) - Summary

CLOTRIMAZOLE SUMMARY

CLOTRIMAZOLE TOPICAL SOLUTION, USP 1%

FOR DERMATOLOGIC USE ONLY
NOT FOR OPHTHALMIC USE

Clotrimazole, USP is a synthetic antifungal agent having the chemical name [1 (o -Chloro-α,α-diphenylbenzyl)imidazole].

Clotrimazole topical solution is indicated for the topical treatment of candidiasis due to Candida Albicans and tinea versicolor due to Malassezia furfur.

Clotrimazole is also available as a nonprescription item which is indicated for the topical treatment of the following dermal infections: tinea pedis, tinea cruris, and tinea corporis due to Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, and Microsporum canis.

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CLOTRIMAZOLE NEWS HIGHLIGHTS

Published Studies Related to Clotrimazole (Clotrimazole Topical)

Comparative efficacy of topical 1% butenafine and 1% clotrimazole in tinea cruris and tinea corporis: a randomized, double-blind trial. [2005]

A clinical multicenter study comparing efficacy and tolerability of topical combination therapy with clotrimazole (Canesten, two formats) with oral single dose fluconazole (Diflucan) in vulvovaginal mycoses. [2004.04]

Clinical comparison of the efficacy and tolerability of once daily Canesten with twice daily Nizoral (clotrimazole 1% cream vs. ketoconazole 2% cream) during a 28-day topical treatment of interdigital tinea pedis. [2002.04]

Clotrimazole increases tacrolimus blood levels: a drug interaction in kidney transplant patients. [2001.04]

A double-blind randomized comparative trial: eberconazole 1% cream versus clotrimazole 1% cream twice daily in Candida and dermatophyte skin infections. [2001]

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Clinical Trials Related to Clotrimazole (Clotrimazole Topical)

Efficacy and Safety Study of Miconazole Lauriad to Treat Oropharyngeal Candidiasis in HIV Patients [Completed]

Randomized Comparative Study of Fluconazole Versus Clotrimazole Troches in the Prevention of Serious Fungal Infection in Patients With AIDS or Advanced AIDS-Related Complex. (A Nested Study of ACTG 081) [Completed]

A Comparison of the Safety and Effectiveness of Fluconazole or Clotrimazole in the Treatment of Fungal Infections of the Mouth and Throat in Patients With AIDS [Completed]

Uptake of the Antifungal Miconazole and Effect on Estrogen Metabolizing Enzymes in Humans [Recruiting]

Comparative Efficacy of Ovule vs Tablet [Recruiting]

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