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Clorpres (Clonidine Hydrochloride / Chlorthalidone) - Summary

 
 



CLORPRES SUMMARY

CLORPRES® is a combination of clonidine hydrochloride (a centrally acting antihypertensive agent) and chlorthalidone (a diuretic). CLORPRES® is available as tablets for oral administration in three dosage strengths: 0.1 mg/15 mg, 0.2 mg/15 mg and 0.3 mg/15 mg of clonidine hydrochloride/chlorthalidone, respectively. The inactive ingredients are ammonium chloride, colloidal silicon dioxide, croscarmellose sodium (Type A), magnesium stearate, microcrystalline cellulose, sodium lauryl sulfate, D&C yellow #10.

CLORPRES® (clonidine hydrochloride USP/chlorthalidone USP) is indicated in the treatment of hypertension. This fixed combination drug is not indicated for initial therapy of hypertension. Hypertension requires therapy titrated to the individual patient. If the fixed combination represents the dosage so determined, its use may be more convenient in patient management. The treatment of hypertension is not static, but must be reevaluated as conditions in each patient warrant.


See all Clorpres indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Clorpres (Clonidine / Chlorthalidone)

Hypertension before the age of 55 increases risk of cardiovascular death
Source: Cardiovascular / Cardiology News From Medical News Today [2017.05.19]
When someone gets diagnosed with hypertension, either early (before the age of 55) or later in life, can have important health ramifications.

Options Emerging for Pulmonary Hypertension, Chronic Cough
Source: Medscape Allergy & Clinical Immunology Headlines [2017.05.15]
Results from the MERIT study evaluating macitentan in pulmonary hypertension will be presented at the American Thoracic Society Conference, along with a study of a P2X3 antagonist for chronic cough.
Medscape Medical News

Simple blood tests lead to improved hypertension treatment in African countries
Source: Hypertension News From Medical News Today [2017.05.04]
Using two simple blood tests, Western University researchers were able to drastically improve treatment for resistant hypertension across three sites in Nigeria, Kenya and South Africa.

Diabetes and hypertension: What is the relationship?
Source: Hypertension News From Medical News Today [2017.04.29]
Hypertension, or high blood pressure, is linked to diabetes, and each condition can make the other worse. How can people reduce the associated risks?

Endocrine Society issues statement to improve detection of curable forms of hypertension
Source: Endocrinology News From Medical News Today [2017.04.10]
A new Scientific Statement issued by the Endocrine Society advises healthcare providers on ways to spot hormonal causes of high blood pressure that can be cured with surgery or treated effectively...

more news >>

Published Studies Related to Clorpres (Clonidine / Chlorthalidone)

The treatment of obese hypertensive black women: a comparative study of chlorthalidone versus clonidine. [1992.05]
OBJECTIVE: We attempted to determine a valid pharmacological approach for the control of high blood pressure in obese hypertensive patients using two antihypertensive agents with different pharmacological actions... CONCLUSIONS: We conclude that a rational approach to the treatment of hypertension in obese black women includes diuretics, a first choice attempt that tries to address the hemodynamic alterations previously identified in those patients. Combining diuretics with an alpha-adrenergic agonist resulted in complete control of blood pressure in most of the hypertensive patients in our study. The lowest dose of each antihypertensive medication, especially when used in combination, was effective in a high percentage of patients. The use of this antihypertensive approach also helps to clarify which of the underlying pathophysiological mechanisms should be targeted when other currently available antihypertensive medications are used.

Efficacy and safety of two-year therapy with transdermal clonidine for essential hypertension. [1988.05]
We evaluated the safety and efficacy of transdermal clonidine (TC) in 23 patients with essential hypertension over a two-year period...

more studies >>


Page last updated: 2017-05-19

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