CLORPRES SUMMARY
CLORPRES® is a combination of clonidine hydrochloride (a centrally acting antihypertensive agent) and chlorthalidone (a diuretic). CLORPRES® is available as tablets for oral administration in three dosage strengths: 0.1 mg/15 mg, 0.2 mg/15 mg and 0.3 mg/15 mg of clonidine hydrochloride/chlorthalidone, respectively.
CLORPRES® (clonidine hydrochloride USP/chlorthalidone USP) is indicated in the treatment of hypertension. This fixed combination drug is not indicated for initial therapy of hypertension. Hypertension requires therapy titrated to the individual patient. If the fixed combination represents the dosage so determined, its use may be more convenient in patient management. The treatment of hypertension is not static, but must be reevaluated as conditions in each patient warrant.
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NEWS HIGHLIGHTSMedia Articles Related to Clorpres (Clonidine / Chlorthalidone)
Seasoning May Cut Salt Needs in Hypertension (CME/CE) Source: MedPage Today Primary Care [2013.05.18] SAN FRANCISCO (MedPage Today) -- A greater taste for salt among older hypertensive adults might be sated by seasoning instead, a small experimental study showed.
Surprising Findings On Hypertension In Adolescents Source: Hypertension News From Medical News Today [2013.05.07] Teenagers with high blood pressure appear to have better psychological adjustment and enjoy higher quality of life than those with normal blood pressure, suggests a study in the May issue of Psychosomatic Medicine: Journal of Biobehavioral Medicine, the official journal of the American Psychosomatic Society...
Safety-Net Clinics Face Challenges Controlling Hypertension In Their Patients Source: Hypertension News From Medical News Today [2013.04.19] Federally funded safety-net clinics for the uninsured lag behind other health care providers in controlling blood pressure among the low-income patients who rely on them for care, a new Michigan State University analysis suggests...
Relationship Between Obesity, Heart Disease And Hypertension Source: Hypertension News From Medical News Today [2013.04.13] Obesity, heart disease, and high blood pressure (hypertension) are all related, but understanding the molecular pathways that underlie cause and effect is complicated...
Preeclampsia (Pregnancy Induced Hypertension) Source: MedicineNet Hydronephrosis Specialty [2012.05.21] Title: Preeclampsia (Pregnancy Induced Hypertension) Category: Diseases and Conditions Created: 11/14/1998 4:06:00 PM Last Editorial Review: 5/21/2012 12:00:00 AM
Published Studies Related to Clorpres (Clonidine / Chlorthalidone)
The treatment of obese hypertensive black women: a comparative study of chlorthalidone versus clonidine. [1992.05] OBJECTIVE: We attempted to determine a valid pharmacological approach for the control of high blood pressure in obese hypertensive patients using two antihypertensive agents with different pharmacological actions... CONCLUSIONS: We conclude that a rational approach to the treatment of hypertension in obese black women includes diuretics, a first choice attempt that tries to address the hemodynamic alterations previously identified in those patients. Combining diuretics with an alpha-adrenergic agonist resulted in complete control of blood pressure in most of the hypertensive patients in our study. The lowest dose of each antihypertensive medication, especially when used in combination, was effective in a high percentage of patients. The use of this antihypertensive approach also helps to clarify which of the underlying pathophysiological mechanisms should be targeted when other currently available antihypertensive medications are used.
Efficacy and safety of two-year therapy with transdermal clonidine for essential hypertension. [1988.05] We evaluated the safety and efficacy of transdermal clonidine (TC) in 23 patients with essential hypertension over a two-year period...
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