Clobevate (Clobetasol Propionate Topical) - Summary

CLOBEVATE SUMMARY

Clobevate® (Clobetasol Propionate Gel) contains the active compound clobetasol propionate, a synthetic corticosteroid, for topical dermatologic use. Clobetasol, an analog of prednisolone, has a high degree of glucocorticoid activity and a slight degree of mineralocorticoid activity.

Clobevate is a super-high potency corticosteroid formulation indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Treatment beyond 2 consecutive weeks is not recommended, and the total dosage should not exceed 50 g per week because of the potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis. Use in children under 12 years of age is not recommended.

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CLOBEVATE NEWS HIGHLIGHTS

Media Articles Related to Clobevate (Clobetasol Topical)

Patient Education Is Key To Managing Atopic Dermatitis
Source: Dermatology News From Medical News Today [2008.11.11]

Experts Reveal The Complexity Of Dermatitis Management
Source: Allergy News From Medical News Today [2008.11.07]

Dermatitis Can Have Many Causes
Source: MedicineNet Allergy Specialty [2008.11.07]

Atopic Dermatitis
Source: MedicineNet Hives Specialty [2008.06.03]

Health Tip: Soothing Eczema (HealthDay)
Source: Y! Health Skin Conditions News [2008.10.29]

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Published Studies Related to Clobevate (Clobetasol Topical)

The efficacy of '0.05% Clobetasol + 2.5% zinc sulphate' cream vs. '0.05% Clobetasol alone' cream in the treatment of the chronic hand eczema: a double-blind study. [2008.05]

A comparative treatment study of topical tacrolimus and clobetasol in oral lichen planus. [2008.02]

Comparison of clinical efficacy of topical tazarotene 0.1% cream with topical clobetasol propionate 0.05% cream in chronic plaque psoriasis: a double-blind, randomized, right-left comparison study. [2007.01]

Clobetasol propionate foam 0.05% as a novel topical formulation for plaque-type and scalp psoriasis. [2007]

Efficacy and safety of a new clobetasol propionate 0.05% foam in alopecia areata: a randomized, double-blind placebo-controlled trial. [2006.11]

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Clinical Trials Related to Clobevate (Clobetasol Topical)

A Comparison Between Clobetasol Propionate 0.05% (Clobex®) Spray and Clobetasol Propionate 0.05% (Olux®) Foam [Completed]

Efficacy, Tolerance and Satisfaction With CLOBEX® Spray When Used as Monotherapy or Add-on Therapy in Plaque Psoriasis [Completed]

Efficacy, Safety, Preference and Response Duration of Clobex® Spray and Taclonex® Ointment in Psoriasis [Completed]

Maintenance Effect of Clobex Shampoo on Subjects With Moderate to Severe Scalp Psoriasis [Completed]

Safety & Effectiveness of Clobex Spray, Followed by Calcitriol Ointment in Management of Plaque Psoriasis [Recruiting]

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