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Clinoril (Sulindac) - Published Studies

 


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Clinoril Related Published Studies

Well-designed clinical trials related to Clinoril (Sulindac)

Concomitant DFMO and sulindac chemoprevention of colorectal adenomas: a major clinical advance. [2008.11]

Difluoromethylornithine Plus Sulindac for the Prevention of Sporadic Colorectal Adenomas: A Randomized Placebo-Controlled, Double-Blind Trial. [2008]

The effect of long-term treatment with sulindac on the progression of diabetic retinopathy. [2007.08]

Genetic polymorphisms of human flavin monooxygenase 3 in sulindac-mediated primary chemoprevention of familial adenomatous polyposis. [2004.12.15]

A double-blind randomized study of fetal side effects during and after the short-term maternal administration of indomethacin, sulindac, and nimesulide for the treatment of preterm labor. [2003.04]

Primary chemoprevention of familial adenomatous polyposis with sulindac. [2002.04.04]

Sulindac to prevent recurrent preterm labor: a randomized controlled trial. [2001.10]

Rectal epithelial apoptosis in familial adenomatous polyposis patients treated with sulindac. [1999.12]

A randomized double-blind study comparing the fetal effects of sulindac to terbutaline during the management of preterm labor. [1999.02]

Comparative effects of nabumetone, sulindac, and ibuprofen on renal function. [1997.06]

Prospective randomized study of sulindac versus calcium and calciferol for upper gastrointestinal polyps in familial adenomatous polyposis. [1996.12]

Tissue prostaglandin levels in familial adenomatous polyposis patients treated with sulindac. [1996.06]

Absorption of sulindac from a novel (Pro-SorbTM) liquid formulation. [1996.04]

The effects of sulindac on colorectal proliferation and apoptosis in familial adenomatous polyposis. [1995.09]

Fetal cardiac function and ductus arteriosus during indomethacin and sulindac therapy for threatened preterm labor: a randomized study. [1995.07]

Outpatient oral sulindac to prevent recurrence of preterm labor. [1995.05]

Effect of sulindac on sporadic colonic polyps. [1995.04]

Comparative effects of nabumetone, sulindac, and indomethacin on urinary prostaglandin excretion and platelet function in volunteers. [1994.11]

Randomized controlled trial of the effect of sulindac on duodenal and rectal polyposis and cell proliferation in patients with familial adenomatous polyposis. [1993.12]

Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis. [1993.05.06]

Randomized comparative trial of indomethacin and sulindac for the treatment of refractory preterm labor. [1992.02]

A comparison of ketoprofen SR and sulindac in the elderly with rheumatoid arthritis. [1992.01]

No adverse effect of non-steroidal anti-inflammatory drugs, sulindac and diclofenac sodium, on blood pressure control with a calcium antagonist, nifedipine, in elderly hypertensive patients. [1991.11]

Sulindac causes regression of rectal polyps in familial adenomatous polyposis. [1991.09]

Effect of sulindac on the cough reflex of healthy subjects. [1991.02]

The effects of enalapril and sulindac on the dermal response to substance P and neurokinin A. [1991.01]

The effects of sulindac and diclofenac in essential hypertension controlled by treatment with a beta blocker and/or diuretic. [1991]

The effect of sulindac on the abnormal cough reflex associated with dry cough. [1990.10]

Effect of naproxen and sulindac on blood pressure response to atenolol. [1990.09]

Renal effects of ibuprofen, piroxicam, and sulindac in patients with asymptomatic renal failure. A prospective, randomized, crossover comparison. [1990.04.15]

Multicentre double-blind study of the efficacy, safety and tolerance of pirazolac compared with sulindac in patients with rheumatoid arthritis. [1990]

Effect of sulindac on angiotensin converting enzyme inhibitor-induced cough: randomised placebo-controlled double-blind cross-over study. [1989.12]

The effects of indomethacin and sulindac upon the blood pressures of individuals with untreated labile or mild hypertension. [1989.08]

Reduced incidence of hyperkalemia and azotemia in patients receiving sulindac compared with indomethacin. [1988]

Effects of the non-steroidal anti-inflammatory drugs, piroxicam or sulindac, on the antihypertensive actions of propranolol and verapamil. [1987.12]

Well-designed clinical trials possibly related to Clinoril (Sulindac)

Rationale for, and design of, a clinical trial targeting polyamine metabolism for colon cancer chemoprevention. [2007.08]

Rationale for, and design of, a clinical trial targeting polyamine metabolism for colon cancer chemoprevention. [2007.03.30]

Sporadic adenomatous polyp regression with exisulind is effective but toxic: a randomised, double blind, placebo controlled, dose-response study. [2006.03]

Prostanoids, ornithine decarboxylase, and polyamines in primary chemoprevention of familial adenomatous polyposis. [2004.02]

Observation on the therapeutic effect of Shu Feng Huo Luo Pian for treatment of osseous arthritis. [2002.03]

Effects of non-steroidal anti-inflammatory drugs on hypertension control using angiotensin converting enzyme inhibitors and thiazide diuretics. [2001.10]

Exisulind, a selective apoptotic antineoplastic drug. [2001.10]

Safety and efficacy of exisulind for treatment of recurrent prostate cancer after radical prostatectomy. [2001.09]

Antihypertensive effect of the combination of fosinopril and HCTZ is resistant to interference by nonsteroidal antiinflammatory drugs. [1999.09]

Effect of estrogen replacement therapy with or without concomitant nonsteroidal anti-inflammatory drugs on pulsatility and resistance index of uterine arteries in healthy postmenopausal women. [1997.07]

Acute and chronic effects of nonsteroidal antiinflammatory drugs on glomerular filtration rate in elderly patients. [1995.11]

Effects of non-steroidal anti-inflammatory drugs on prostacyclin and thromboxane biosynthesis in patients with mild essential hypertension. [1990.10]

Non-steroidal anti-inflammatory drugs as the first step in cancer pain therapy: double-blind, within-patient study comparing nine drugs. [1990.01]

Antihypertensive effect of enalapril in essential hypertension: role of prostacyclin. [1987.12]

Other research related to Clinoril (Sulindac)

Combination treatment with arsenic trioxide and sulindac enhances apoptotic cell death in lung cancer cells via activation of oxidative stress and mitogen-activated protein kinases. [2008.08]

The proapoptotic effects of sulindac, sulindac sulfone and indomethacin are mediated by nucleolar translocation of the RelA(p65) subunit of NF-kappaB. [2008.04.17]

Comparative Bioavailability of Sulindac in Capsule and Tablet Formulations. [2008.03]

Aseptic meningitis associated with chronic sulindac use for osteoarthritis: a case report. [2008.02]

Sulindac prevents esophageal adenocarcinomas induced by gastroduodenal reflux in rats. [2007.12.31]

Anti-angiogenic properties of a sulindac analogue. [2007.12]

Sulindac loaded alginate beads for a mucoprotective and controlled drug release. [2007.06]

Sulindac treatment in hereditary non-polyposis colorectal cancer. [2007.05]

Sulindac treatment in hereditary non-polyposis colorectal cancer. [2007.04.13]

Sulindac induces apoptosis and inhibits tumor growth in vivo in head and neck squamous cell carcinoma. [2007.03]

A phase I clinical and pharmacokinetic study of the multi-drug resistance protein-1 (MRP-1) inhibitor sulindac, in combination with epirubicin in patients with advanced cancer. [2007.01]

Dietary anthocyanin-rich tart cherry extract inhibits intestinal tumorigenesis in APC(Min) mice fed suboptimal levels of sulindac. [2006.12.13]

Synergistic induction of apoptosis by sulindac and arsenic trioxide in human lung cancer A549 cells via reactive oxygen species-dependent down-regulation of survivin. [2006.11.15]

High perinatal survival in monoamniotic twins managed by prophylactic sulindac, intensive ultrasound surveillance, and Cesarean delivery at 32 weeks' gestation. [2006.10]

A phase I clinical and pharmacokinetic study of the multi-drug resistance protein-1 (MRP-1) inhibitor sulindac, in combination with epirubicin in patients with advanced cancer. [2006.04.27]

MF tricyclic and sulindac retard tumor formation in an animal model. [2006.01.01]

Effect of the non-steroidal anti-inflammatory drug sulindac on colorectal adenomas of uncolectomized familial adenomatous polyposis. [2006.01]

Dietary putrescine reduces the intestinal anticarcinogenic activity of sulindac in a murine model of familial adenomatous polyposis. [2006]

Genetic polymorphisms of flavin monooxygenase 3 in sulindac-induced regression of colorectal adenomas in familial adenomatous polyposis. [2005.10]

[The effects of sulindac on the pathology of colorectal remnant polyps of familial adenomatous polyposis (FAP) patients] [2005.08.18]

The influence of sulindac on diabetic cardiomyopathy: a non-invasive evaluation by Doppler echocardiography in streptozotocin-induced diabetic rats. [2005.08]

Sulindac inhibits beta-catenin expression in normal-appearing colon of hereditary nonpolyposis colorectal cancer and familial adenomatous polyposis patients. [2005.07]

Sulindac induces apoptosis and protects against colon carcinoma in mice. [2005.05.14]

Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-kappa B pathway in pancreatic carcinoma cells. [2005.04]

Sulindac sulfide-induced apoptosis in sinonasal cancer cells. [2005.02]

Ursodeoxycholate/Sulindac combination treatment effectively prevents intestinal adenomas in a mouse model of polyposis. [2004.09]

Combined effect of arsenic trioxide and sulindac sulfide in A549 human lung cancer cells in vitro. [2004.06]

Photoprotective effects of sulindac against ultraviolet B-induced phototoxicity in the skin of SKH-1 hairless mice. [2004.03.15]

Increased anti-tumour efficacy of doxorubicin when combined with sulindac in a xenograft model of an MRP-1-positive human lung cancer. [2004.03]

Sulindac improves memory and increases NMDA receptor subunits in aged Fischer 344 rats. [2004.03]

High-dose tamoxifen and sulindac as first-line treatment for desmoid tumors. [2004.02.01]

Regional response leading to tumorigenesis after sulindac in small and large intestine of mice with Apc mutations. [2003.03]

Inhibition of the phosphatidylinositol 3'-kinase signaling pathway increases the responsiveness of pancreatic carcinoma cells to sulindac. [2003.03]

The influence of sulindac on patients with primary biliary cirrhosis that responds incompletely to ursodeoxycholic acid: a pilot study. [2002.12]

Effects of long-term administration of sulindac on APC mRNA and apoptosis in colons of rats treated with azoxymethane. [2002.11]

Effect of sulindac treatment for attenuated familial adenomatous polyposis with a new germline APC mutation at codon 161: report of a case. [2002.10]

Phase I and pharmacokinetic trial of the proapoptotic sulindac analog CP-461 in patients with advanced cancer. [2002.10]

[Rectal carcinoma in a patient with familial adenomatous polyposis coli after colectomy with ileorectal anastomosis and consecutive chemoprevention with sulindac suppositories] [2002.08]

Synergistic effects of (-)-epigallocatechin gallate with sulindac against colon carcinogenesis of rats treated with azoxymethane. [2002.03.08]

Long-term treatment with sulindac in familial adenomatous polyposis: a prospective cohort study. [2002.03]

Effects of betamethasone, sulindac and quinacrine drugs on the inflammatory neoangiogenesis response induced by polyurethane sponge implanted in mouse. [2002]

Nerve pathology in the type 1 diabetic dog: effects of treatment with sulindac. [2001.12]

Molecular analysis of sulindac-resistant adenomas in familial adenomatous polyposis. [2001.12]

Complete regression of colonic adenomas after treatment with sulindac in Gardner's syndrome: a 4-year follow-up. [2001.11]

Relationship between APC genotype, polyp distribution, and oral sulindac treatment in the colon and rectum of patients with familial adenomatous polyposis. [2001.08]

Enhanced apoptosis and transforming growth factor-beta1 expression in colorectal adenomas and carcinomas after Sulindac therapy. [2001.07]

Sulindac and its derivatives: a novel class of anticancer agents. [2001.05]

Sulindac in familial adenomatous polyposis: evaluation by nuclear morphometry. [2001.05]

Bowen's disease (squamous cell carcinoma in situ) in immunosuppressed patients treated with imiquimod 5% cream and a cox inhibitor, sulindac: potential applications for this combination of immunotherapy. [2001.02]

Long-term treatment with sulindac in familial adenomatous polyposis: is there an actual efficacy in prevention of rectal cancer? [2000.05]

Sulindac and exisulind exhibit a significant antiproliferative effect and induce apoptosis in human hepatocellular carcinoma cell lines. [2000.04.15]

Inhibition of rat colon tumors by sulindac and sulindac sulfone is independent of K-ras (codon 12) mutation. [2000.02]

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