Clinoril Related Published Studies
Well-designed clinical trials related to Clinoril (Sulindac)
Concomitant DFMO and sulindac chemoprevention of colorectal adenomas: a major clinical advance. [2008.11]
Difluoromethylornithine Plus Sulindac for the Prevention of Sporadic Colorectal Adenomas: A Randomized Placebo-Controlled, Double-Blind Trial. [2008]
The effect of long-term treatment with sulindac on the progression of diabetic retinopathy. [2007.08]
Genetic polymorphisms of human flavin monooxygenase 3 in sulindac-mediated primary chemoprevention of familial adenomatous polyposis. [2004.12.15]
A double-blind randomized study of fetal side effects during and after the short-term maternal administration of indomethacin, sulindac, and nimesulide for the treatment of preterm labor. [2003.04]
Primary chemoprevention of familial adenomatous polyposis with sulindac. [2002.04.04]
Sulindac to prevent recurrent preterm labor: a randomized controlled trial. [2001.10]
Rectal epithelial apoptosis in familial adenomatous polyposis patients treated with sulindac. [1999.12]
A randomized double-blind study comparing the fetal effects of sulindac to terbutaline during the management of preterm labor. [1999.02]
Comparative effects of nabumetone, sulindac, and ibuprofen on renal function. [1997.06]
Prospective randomized study of sulindac versus calcium and calciferol for upper gastrointestinal polyps in familial adenomatous polyposis. [1996.12]
Tissue prostaglandin levels in familial adenomatous polyposis patients treated with sulindac. [1996.06]
Absorption of sulindac from a novel (Pro-SorbTM) liquid formulation. [1996.04]
The effects of sulindac on colorectal proliferation and apoptosis in familial adenomatous polyposis. [1995.09]
Fetal cardiac function and ductus arteriosus during indomethacin and sulindac therapy for threatened preterm labor: a randomized study. [1995.07]
Outpatient oral sulindac to prevent recurrence of preterm labor. [1995.05]
Effect of sulindac on sporadic colonic polyps. [1995.04]
Comparative effects of nabumetone, sulindac, and indomethacin on urinary prostaglandin excretion and platelet function in volunteers. [1994.11]
Randomized controlled trial of the effect of sulindac on duodenal and rectal polyposis and cell proliferation in patients with familial adenomatous polyposis. [1993.12]
Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis. [1993.05.06]
Randomized comparative trial of indomethacin and sulindac for the treatment of refractory preterm labor. [1992.02]
A comparison of ketoprofen SR and sulindac in the elderly with rheumatoid arthritis. [1992.01]
No adverse effect of non-steroidal anti-inflammatory drugs, sulindac and diclofenac sodium, on blood pressure control with a calcium antagonist, nifedipine, in elderly hypertensive patients. [1991.11]
Sulindac causes regression of rectal polyps in familial adenomatous polyposis. [1991.09]
Effect of sulindac on the cough reflex of healthy subjects. [1991.02]
The effects of enalapril and sulindac on the dermal response to substance P and neurokinin A. [1991.01]
The effects of sulindac and diclofenac in essential hypertension controlled by treatment with a beta blocker and/or diuretic. [1991]
The effect of sulindac on the abnormal cough reflex associated with dry cough. [1990.10]
Effect of naproxen and sulindac on blood pressure response to atenolol. [1990.09]
Renal effects of ibuprofen, piroxicam, and sulindac in patients with asymptomatic renal failure. A prospective, randomized, crossover comparison. [1990.04.15]
Multicentre double-blind study of the efficacy, safety and tolerance of pirazolac compared with sulindac in patients with rheumatoid arthritis. [1990]
Effect of sulindac on angiotensin converting enzyme inhibitor-induced cough: randomised placebo-controlled double-blind cross-over study. [1989.12]
The effects of indomethacin and sulindac upon the blood pressures of individuals with untreated labile or mild hypertension. [1989.08]
Reduced incidence of hyperkalemia and azotemia in patients receiving sulindac compared with indomethacin. [1988]
Effects of the non-steroidal anti-inflammatory drugs, piroxicam or sulindac, on the antihypertensive actions of propranolol and verapamil. [1987.12]
Well-designed clinical trials possibly related to Clinoril (Sulindac)
Rationale for, and design of, a clinical trial targeting polyamine metabolism for colon cancer chemoprevention. [2007.08]
Rationale for, and design of, a clinical trial targeting polyamine metabolism for colon cancer chemoprevention. [2007.03.30]
Sporadic adenomatous polyp regression with exisulind is effective but toxic: a randomised, double blind, placebo controlled, dose-response study. [2006.03]
Prostanoids, ornithine decarboxylase, and polyamines in primary chemoprevention of familial adenomatous polyposis. [2004.02]
Observation on the therapeutic effect of Shu Feng Huo Luo Pian for treatment of osseous arthritis. [2002.03]
Effects of non-steroidal anti-inflammatory drugs on hypertension control using angiotensin converting enzyme inhibitors and thiazide diuretics. [2001.10]
Exisulind, a selective apoptotic antineoplastic drug. [2001.10]
Safety and efficacy of exisulind for treatment of recurrent prostate cancer after radical prostatectomy. [2001.09]
Antihypertensive effect of the combination of fosinopril and HCTZ is resistant to interference by nonsteroidal antiinflammatory drugs. [1999.09]
Effect of estrogen replacement therapy with or without concomitant nonsteroidal anti-inflammatory drugs on pulsatility and resistance index of uterine arteries in healthy postmenopausal women. [1997.07]
Acute and chronic effects of nonsteroidal antiinflammatory drugs on glomerular filtration rate in elderly patients. [1995.11]
Effects of non-steroidal anti-inflammatory drugs on prostacyclin and thromboxane biosynthesis in patients with mild essential hypertension. [1990.10]
Non-steroidal anti-inflammatory drugs as the first step in cancer pain therapy: double-blind, within-patient study comparing nine drugs. [1990.01]
Antihypertensive effect of enalapril in essential hypertension: role of prostacyclin. [1987.12]
Other research related to Clinoril (Sulindac)
Combination treatment with arsenic trioxide and sulindac enhances apoptotic cell death in lung cancer cells via activation of oxidative stress and mitogen-activated protein kinases. [2008.08]
The proapoptotic effects of sulindac, sulindac sulfone and indomethacin are mediated by nucleolar translocation of the RelA(p65) subunit of NF-kappaB. [2008.04.17]
Comparative Bioavailability of Sulindac in Capsule and Tablet Formulations. [2008.03]
Aseptic meningitis associated with chronic sulindac use for osteoarthritis: a case report. [2008.02]
Sulindac prevents esophageal adenocarcinomas induced by gastroduodenal reflux in rats. [2007.12.31]
Anti-angiogenic properties of a sulindac analogue. [2007.12]
Sulindac loaded alginate beads for a mucoprotective and controlled drug release. [2007.06]
Sulindac treatment in hereditary non-polyposis colorectal cancer. [2007.05]
Sulindac treatment in hereditary non-polyposis colorectal cancer. [2007.04.13]
Sulindac induces apoptosis and inhibits tumor growth in vivo in head and neck squamous cell carcinoma. [2007.03]
A phase I clinical and pharmacokinetic study of the multi-drug resistance protein-1 (MRP-1) inhibitor sulindac, in combination with epirubicin in patients with advanced cancer. [2007.01]
Dietary anthocyanin-rich tart cherry extract inhibits intestinal tumorigenesis in APC(Min) mice fed suboptimal levels of sulindac. [2006.12.13]
Synergistic induction of apoptosis by sulindac and arsenic trioxide in human lung cancer A549 cells via reactive oxygen species-dependent down-regulation of survivin. [2006.11.15]
High perinatal survival in monoamniotic twins managed by prophylactic sulindac, intensive ultrasound surveillance, and Cesarean delivery at 32 weeks' gestation. [2006.10]
A phase I clinical and pharmacokinetic study of the multi-drug resistance protein-1 (MRP-1) inhibitor sulindac, in combination with epirubicin in patients with advanced cancer. [2006.04.27]
MF tricyclic and sulindac retard tumor formation in an animal model. [2006.01.01]
Effect of the non-steroidal anti-inflammatory drug sulindac on colorectal adenomas of uncolectomized familial adenomatous polyposis. [2006.01]
Dietary putrescine reduces the intestinal anticarcinogenic activity of sulindac in a murine model of familial adenomatous polyposis. [2006]
Genetic polymorphisms of flavin monooxygenase 3 in sulindac-induced regression of colorectal adenomas in familial adenomatous polyposis. [2005.10]
[The effects of sulindac on the pathology of colorectal remnant polyps of familial adenomatous polyposis (FAP) patients] [2005.08.18]
The influence of sulindac on diabetic cardiomyopathy: a non-invasive evaluation by Doppler echocardiography in streptozotocin-induced diabetic rats. [2005.08]
Sulindac inhibits beta-catenin expression in normal-appearing colon of hereditary nonpolyposis colorectal cancer and familial adenomatous polyposis patients. [2005.07]
Sulindac induces apoptosis and protects against colon carcinoma in mice. [2005.05.14]
Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-kappa B pathway in pancreatic carcinoma cells. [2005.04]
Sulindac sulfide-induced apoptosis in sinonasal cancer cells. [2005.02]
Ursodeoxycholate/Sulindac combination treatment effectively prevents intestinal adenomas in a mouse model of polyposis. [2004.09]
Combined effect of arsenic trioxide and sulindac sulfide in A549 human lung cancer cells in vitro. [2004.06]
Photoprotective effects of sulindac against ultraviolet B-induced phototoxicity in the skin of SKH-1 hairless mice. [2004.03.15]
Increased anti-tumour efficacy of doxorubicin when combined with sulindac in a xenograft model of an MRP-1-positive human lung cancer. [2004.03]
Sulindac improves memory and increases NMDA receptor subunits in aged Fischer 344 rats. [2004.03]
High-dose tamoxifen and sulindac as first-line treatment for desmoid tumors. [2004.02.01]
Regional response leading to tumorigenesis after sulindac in small and large intestine of mice with Apc mutations. [2003.03]
Inhibition of the phosphatidylinositol 3'-kinase signaling pathway increases the responsiveness of pancreatic carcinoma cells to sulindac. [2003.03]
The influence of sulindac on patients with primary biliary cirrhosis that responds incompletely to ursodeoxycholic acid: a pilot study. [2002.12]
Effects of long-term administration of sulindac on APC mRNA and apoptosis in colons of rats treated with azoxymethane. [2002.11]
Effect of sulindac treatment for attenuated familial adenomatous polyposis with a new germline APC mutation at codon 161: report of a case. [2002.10]
Phase I and pharmacokinetic trial of the proapoptotic sulindac analog CP-461 in patients with advanced cancer. [2002.10]
[Rectal carcinoma in a patient with familial adenomatous polyposis coli after colectomy with ileorectal anastomosis and consecutive chemoprevention with sulindac suppositories] [2002.08]
Synergistic effects of (-)-epigallocatechin gallate with sulindac against colon carcinogenesis of rats treated with azoxymethane. [2002.03.08]
Long-term treatment with sulindac in familial adenomatous polyposis: a prospective cohort study. [2002.03]
Effects of betamethasone, sulindac and quinacrine drugs on the inflammatory neoangiogenesis response induced by polyurethane sponge implanted in mouse. [2002]
Nerve pathology in the type 1 diabetic dog: effects of treatment with sulindac. [2001.12]
Molecular analysis of sulindac-resistant adenomas in familial adenomatous polyposis. [2001.12]
Complete regression of colonic adenomas after treatment with sulindac in Gardner's syndrome: a 4-year follow-up. [2001.11]
Relationship between APC genotype, polyp distribution, and oral sulindac treatment in the colon and rectum of patients with familial adenomatous polyposis. [2001.08]
Enhanced apoptosis and transforming growth factor-beta1 expression in colorectal adenomas and carcinomas after Sulindac therapy. [2001.07]
Sulindac and its derivatives: a novel class of anticancer agents. [2001.05]
Sulindac in familial adenomatous polyposis: evaluation by nuclear morphometry. [2001.05]
Bowen's disease (squamous cell carcinoma in situ) in immunosuppressed patients treated with imiquimod 5% cream and a cox inhibitor, sulindac: potential applications for this combination of immunotherapy. [2001.02]
Long-term treatment with sulindac in familial adenomatous polyposis: is there an actual efficacy in prevention of rectal cancer? [2000.05]
Sulindac and exisulind exhibit a significant antiproliferative effect and induce apoptosis in human hepatocellular carcinoma cell lines. [2000.04.15]
Inhibition of rat colon tumors by sulindac and sulindac sulfone is independent of K-ras (codon 12) mutation. [2000.02]
|