Clindets® (Clindamycin Phosphate Pledgets) contain clindamycin phosphate, USP at a concentration equivalent to 10 mg clindamycin per milliliter in a vehicle of isopropyl alcohol 52% v/v, propylene glycol and water. Each Clindets® pledget applicator contains approximately 1 mL of Clindamycin Phosphate Topical Solution. Clindamycin Phosphate Topical Solution has a pH range between 4.0 and 7.0.
Clindets are indicated in the treatment of acne vulgaris. In view of the potential for diarrhea, bloody diarrhea and pseudomembranous colitis, the physician should consider whether other agents are more appropriate. (See CONTRAINDICATIONS, WARNINGS, and ADVERSE REACTIONS.)
Media Articles Related to Clindets (Clindamycin Topical)
Surprising link discovered between chloracne and a molecule that protects cells against stress
Source: Dermatology News From Medical News Today [2014.02.10]
ETH-Zurich researchers have discovered a new, surprising link between chloracne and a molecule that protects cells against stress: if Nrf2 gets out of control, disfiguring cysts form on the skin.The images were seen all over the world and stuck in the minds of many: in the autumn of 2004, former President of the Ukraine, Viktor Yushchenko, was poisoned with a high dose of dioxin.
Treating autoimmune and transplant patients with the vitamin a used in acne medicines
Source: Transplants / Organ Donations News From Medical News Today [2014.02.03]
The same form of Vitamin A used by teenagers to combat acne might offer benefits that are more than skin deep. That's because an international team of researchers have found that it may also help keep the immune system under control for people with autoimmune disorders or those who have received transplants. This finding was published in the February 2014 issue of the Journal of Leukocyte Biology.
Health Tip: Taming Acne
Source: MedicineNet Acne Specialty [2014.01.10]
Title: Health Tip: Taming Acne
Category: Health News
Created: 1/10/2014 7:35:00 AM
Last Editorial Review: 1/10/2014 12:00:00 AM
Acne Pictures Slideshow: Causes, Solutions and Treatments for Adults
Source: MedicineNet Acne Specialty [2013.11.21]
Title: Acne Pictures Slideshow: Causes, Solutions and Treatments for Adults
Created: 9/15/2011 3:45:00 PM
Last Editorial Review: 11/21/2013 12:00:00 AM
Clear Skin Pictures Slideshow: Helping Your Teen With Acne
Source: MedicineNet Boils Specialty [2013.11.07]
Title: Clear Skin Pictures Slideshow: Helping Your Teen With Acne
Created: 1/20/2010 3:54:00 PM
Last Editorial Review: 11/7/2013 12:00:00 AM
Published Studies Related to Clindets (Clindamycin Topical)
A randomized, double-blind, placebo-controlled, pilot study to assess the
efficacy and safety of clindamycin 1.2% and tretinoin 0.025% combination gel for
the treatment of acne rosacea over 12 weeks. 
rosacea after 12 weeks of usage... CONCLUSIONS: A combination gel of clindamycin phosphate 1.2% and tretinoin 0.025%
Efficacy and safety of topical nadifloxacin and benzoyl peroxide versus clindamycin and benzoyl peroxide in acne vulgaris: A randomized controlled trial. [2011.11]
BACKGROUND: Topical therapy with comedolytics and antibiotics are often advocated for mild and moderate severity acne vulgaris. Nadifloxacin, a new fluoroquinolone with anti-Propionibacterium acnes activity and additional anti-inflammatory activity, is approved for use in acne. This randomized controlled assessor blind trial compared the clinical effectiveness and safety of eight weeks therapy of nadifloxacin 1% versus clindamycin 1% as add-on therapy to benzoyl peroxide (2.5%) in mild to moderate grade acne... CONCLUSIONS: Topical nadifloxacin, a new fluoroquinolone is effective, tolerable, and safe for mild o moderate facial acne. Its clinical effectiveness is comparable to clindamycin when used as add-on therapy to benzoyl peroxide.
Efficacy of topical combination of benzoyl peroxide 5% and clindamycin 1% for the treatment of progressive macular hypomelanosis: a randomized, doubleblind, placebo-controlled trial. [2011.02]
BACKGROUND: Progressive macular hypomelanosis is a dermatosis without definite etiology. There is no consensus or first-line therapy in the treatment of progressive macular hypomelanosis, and the treatment options used are very little effective. OBJECTIVE: To evaluate the therapeutic efficacy of the topical combination of benzoyl peroxide 5% and clindamycin 1% associated with sun exposure for the treatment of progressive macular hypomelanosis... CONCLUSION: The topical combination of benzoyl peroxide 5% and clindamycin 1% is effective in the treatment of progressive macular hypomelanosis.
Topical clindamycin 1% vs. linoleic acid-rich phosphatidylcholine and
nicotinamide 4% in the treatment of acne: a multicentre-randomized trial. 
It has been shown that topical linoleic acid rich-phosphatidylcholine seems to be
effective in normalization of follicular hyperkeratinization, whereas
nicotinamide has an interesting anti-inflammatory effect. However, little is
known about their combined effect on acne.Four percentage N-PHCL cosmetic
treatment resulted slightly superior to topical clindamycin with all the
parameters studied for its better compliance and the global clinical improvement.
Combination of azelaic acid 5% and clindamycin 2% for the treatment of acne
vulgaris... CONCLUSION: The profound reduction in lesion count and ASI by
Clinical Trials Related to Clindets (Clindamycin Topical)
A Study Comparing Combination Clindamycin Phosphate/Tretinoin Gel Alone Versus With Benzoyl Peroxide Foaming Cloths for Facial Acne [Recruiting]
There are many different factors that cause acne. So combination treatment using different
medications that can address these different factors is commonly used to treat acne.
Fixed-dose combination clindamycin phosphate 1. 2% and tretinoin 0. 025% gel and benzoyl
peroxide 6% foaming cloths are both used to treat acne. This study will evaluate the use of
the medications when used together.
Dalacin-T Gel Post Approval Study [Completed]
Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated Plasmodium Falciparum Malaria [Not yet recruiting]
Few efficient drugs for malaria treatment are available so far. Due to increased exposure of
these drugs and due to the high risk of development of drug resistant strains of Plasmodium
falciparum, new drug combinations have to be actively investigated. The investigators will
test the efficiency, safety and tolerance of combined fosmidomycin and clindamycin treatment
in acute uncomplicated malaria in children aged 3-10 years.
Fosmidomycin With Clindamycin or With Clindamycin Plus Artesunate [Not yet recruiting]
The aim of this study is to evaluate the role of clindamycin and artesunate as possible
combination partners for fosmidomycin to protect it from its susceptibility to recrudescent
infections when used as monotherapy for acute Plasmodium falciparum malaria while retaining
its excellent safety profile
Safety and Efficacy Study of Clindamycin Phosphate 1.2% and Tretinoin 0.025% Gel to Treat Rosacea [Recruiting]
The purpose of this study is to determine whether Clindamycin Phosphate 1. 2% And Tretinoin
0. 025% Gel are effective and safe in the treatment of papulopustular rosacea.