Clindagel (Clindamycin Phosphate Topical Gel) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

In the one well-controlled clinical study comparing Clindagel^® and its vehicle, the incidence of skin and appendages adverse events occurring in >/=1% of the patients in either group is presented below:

Orally and parenterally administered clindamycin has been associated with severe colitis, which may end fatally.

Cases of diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported as adverse reactions in patients treated with oral and parenteral formulations of clindamycin and rarely with topical clindamycin (see WARNINGS). Abdominal pain and gastrointestinal disturbances, as well as Gram-negative folliculitis, have also been reported in association with the use of topical formulations of clindamycin.