CITANEST PLAIN SUMMARY
4% Citanest Plain Dental (prilocaine HCl Injection, USP), is a sterile, non pyrogenic isotonic solution that contains a local anesthetic agent and is administered parenterally by injection.
4% Citanest Plain Dental Injection is indicated for the production of local anesthesia in dentistry by nerve block or infiltration techniques. Only accepted procedures for these techniques as described in standard textbooks are recommended.
Published Studies Related to Citanest Plain (Prilocaine Dental)
Comparison of the efficacy of articaine and prilocaine local anaesthesia for pulpotomy of maxillary and mandibular primary molars. [2011.06]
AIM: The aim of this study was to compare the local anaesthetic efficacy of articaine HCl and prilocaine HCl during an operative procedure after their administration by either mandibular nerve block or maxillary infiltration... CONCLUSION: We concluded that local anaesthesia following mandibular nerve block is more effective than that following maxillary infiltration in 6-8-year-old children. However, the intensity of pain that was experienced by the children during administration of either prilocaine or articaine and some of the dental procedures after their administration were similar.
Anesthetic efficacy of liposomal prilocaine in maxillary infiltration anesthesia. [2011.03]
Animal studies have shown that liposome encapsulation increases prilocaine anesthetic efficacy. This randomized, blind, crossover, three-period study evaluated the anesthetic efficacy of liposome-encapsulated 3% prilocaine, compared to 3% plain prilocaine and 3% prilocaine with 0.03IU/mL felypressin, after a 1.8-mL infiltration in the buccal sulcus of the maxillary right canine, in 32 volunteers...
Spinal anaesthesia for ambulatory arthroscopic surgery of the knee: a comparison of low-dose prilocaine and fentanyl with bupivacaine and fentanyl. [2011.02]
BACKGROUND: Prospective data on the use of prilocaine for ambulatory spinal anaesthesia remain limited. We compared the behaviour and characteristics of subarachnoid block using prilocaine and fentanyl with that of bupivacaine and fentanyl... CONCLUSIONS: The combination of prilocaine and fentanyl is a better alternative to that of low-dose bupivacaine and fentanyl, for spinal anaesthesia in ambulatory arthroscopic knee surgery.
A prospective, double-blinded, randomized, clinical trial comparing the efficacy of 40 mg and 60 mg hyperbaric 2% prilocaine versus 60 mg plain 2% prilocaine for intrathecal anesthesia in ambulatory surgery. [2010.08]
BACKGROUND: In this prospective, double-blind, randomized trial we compared 60 mg and 40 mg of 2% hyperbaric prilocaine with 60 mg of 2% plain prilocaine for spinal anesthesia in terms of sensory block onset in outpatients undergoing elective short-duration (<60 minutes) surgery under spinal anesthesia... CONCLUSIONS: Spinal anesthesia with 60 mg or 40 mg of 2% hyperbaric prilocaine is comparable to 60 mg of 2% plain prilocaine in terms of onset of sensory block at T10. The hyperbaric solution showed faster times to motor block onset and shorter duration of surgical block, suggesting its superiority for the ambulatory setting.
A prospective, double-blinded, randomized, clinical trial comparing the efficacy
of 40 mg and 60 mg hyperbaric 2% prilocaine versus 60 mg plain 2% prilocaine for
intrathecal anesthesia in ambulatory surgery. 
elective short-duration (<60 minutes) surgery under spinal anesthesia... CONCLUSIONS: Spinal anesthesia with 60 mg or 40 mg of 2% hyperbaric prilocaine is
Clinical Trials Related to Citanest Plain (Prilocaine Dental)
Discharge Conditions of Spinal Anesthesia With Heavy Prilocaine-Fentanyl and Heavy Bupivacaine-Fentanyl [Completed]
In this prospective randomized study the investigators aimed to investigate difference of
the duration of spinal anesthesia, discharge times and efficacy between low dose heavy
Prilocaine-Fentanyl and heavy Bupivacaine-Fentanyl in outpatient minor anal surgery.
Methemoglobin Levels in Generally Anesthetized Pediatric Dental Patients Receiving Local Anesthetics [Completed]
To establish and compare maximum methemoglobin blood levels and times to maximum
methemoglobin blood levels following the administration of the injectable local anesthetics
prilocaine and lidocaine when used for dental treatment in pediatric patients under general
anesthesia. Patients will be randomized into three equal study groups. Two of the study
groups will receive local anesthetic and the third group will not. Methemoglobin blood
levels will be non-invasively monitored and recorded throughout dental treatment for all
groups using a Masimo Radical-7 Pulse Co-Oximeter device.
Lidocaine-Prilocaine (EMLA) Cream as Analgesia in Hysterosalpingography Practice [Not yet recruiting]
7% Lidocaine/7% Tetracaine Cream Versus 2,5% Lidocaine / 2,5% Prilocaine Cream [Recruiting]
Lidocaine-Prilocaine (EMLA) Cream as Analgesia in Hysteroscopy Practice [Completed]