Media Articles Related to Citanest Plain (Prilocaine Dental)
Are the cognitive side effects of anesthesia overlooked?
Source: Medical Devices / Diagnostics News From Medical News Today [2014.08.19]
Although guidelines are commonly in place to minimize pain-related side effects of anesthesia, a new survey finds that less attention is paid to the risk of cognitive side effects.
For pediatric knee surgery, regional anesthesia reduces pain, speeds recovery
Source: Bones / Orthopedics News From Medical News Today [2014.08.14]
A recent study of an ultrasound-guided regional anesthesia technique, called femoral nerve block, shows that it leads to less opioid use and allows the majority of patients to go home within hours of...
Dopamine release from ventral tegmental area may help speed emergence from anesthesia, avoid complications
Source: Pain / Anesthetics News From Medical News Today [2014.07.31]
Stimulating one of two dopamine-producing regions in the brain was able to arouse animals receiving general anesthesia with either isoflurane or propofol.
The disruptive effects of anesthesia on brain cell connections are likely temporary
Source: Pain / Anesthetics News From Medical News Today [2014.07.30]
A study of juvenile rat brain cells suggests that the effects of a commonly used anesthetic drug on the connections between brain cells are temporary.
'Ramp control' algorithm simplifies preoperative test for patients with severe sleep apnea
Source: Pain / Anesthetics News From Medical News Today [2014.08.01]
New anesthesia technique helps show cause of obstruction in sleep apneaA simplified anesthesia procedure may enable more widespread use of preoperative testing to demonstrate the cause of airway...
Published Studies Related to Citanest Plain (Prilocaine Dental)
Comparison of the efficacy of articaine and prilocaine local anaesthesia for pulpotomy of maxillary and mandibular primary molars. [2011.06]
AIM: The aim of this study was to compare the local anaesthetic efficacy of articaine HCl and prilocaine HCl during an operative procedure after their administration by either mandibular nerve block or maxillary infiltration... CONCLUSION: We concluded that local anaesthesia following mandibular nerve block is more effective than that following maxillary infiltration in 6-8-year-old children. However, the intensity of pain that was experienced by the children during administration of either prilocaine or articaine and some of the dental procedures after their administration were similar.
Anesthetic efficacy of liposomal prilocaine in maxillary infiltration anesthesia. [2011.03]
Animal studies have shown that liposome encapsulation increases prilocaine anesthetic efficacy. This randomized, blind, crossover, three-period study evaluated the anesthetic efficacy of liposome-encapsulated 3% prilocaine, compared to 3% plain prilocaine and 3% prilocaine with 0.03IU/mL felypressin, after a 1.8-mL infiltration in the buccal sulcus of the maxillary right canine, in 32 volunteers...
Spinal anaesthesia for ambulatory arthroscopic surgery of the knee: a comparison of low-dose prilocaine and fentanyl with bupivacaine and fentanyl. [2011.02]
BACKGROUND: Prospective data on the use of prilocaine for ambulatory spinal anaesthesia remain limited. We compared the behaviour and characteristics of subarachnoid block using prilocaine and fentanyl with that of bupivacaine and fentanyl... CONCLUSIONS: The combination of prilocaine and fentanyl is a better alternative to that of low-dose bupivacaine and fentanyl, for spinal anaesthesia in ambulatory arthroscopic knee surgery.
A prospective, double-blinded, randomized, clinical trial comparing the efficacy of 40 mg and 60 mg hyperbaric 2% prilocaine versus 60 mg plain 2% prilocaine for intrathecal anesthesia in ambulatory surgery. [2010.08]
BACKGROUND: In this prospective, double-blind, randomized trial we compared 60 mg and 40 mg of 2% hyperbaric prilocaine with 60 mg of 2% plain prilocaine for spinal anesthesia in terms of sensory block onset in outpatients undergoing elective short-duration (<60 minutes) surgery under spinal anesthesia... CONCLUSIONS: Spinal anesthesia with 60 mg or 40 mg of 2% hyperbaric prilocaine is comparable to 60 mg of 2% plain prilocaine in terms of onset of sensory block at T10. The hyperbaric solution showed faster times to motor block onset and shorter duration of surgical block, suggesting its superiority for the ambulatory setting.
A prospective, double-blinded, randomized, clinical trial comparing the efficacy
of 40 mg and 60 mg hyperbaric 2% prilocaine versus 60 mg plain 2% prilocaine for
intrathecal anesthesia in ambulatory surgery. 
elective short-duration (<60 minutes) surgery under spinal anesthesia... CONCLUSIONS: Spinal anesthesia with 60 mg or 40 mg of 2% hyperbaric prilocaine is
Clinical Trials Related to Citanest Plain (Prilocaine Dental)
Lidocaine-Prilocaine (EMLA) Cream as Analgesia in Hysterosalpingography Practice [Not yet recruiting]
Efficacy Trial of Eutectic Lidocaine/Prilocaine Cream 5% (EMLA) for Analgesia Prior to Cryotherapy of Verrucae Plantaris [Recruiting]
The investigators main purpose is to assess the efficacy of analgesia provide by topical
lidocaine/prilocaine cream 5% (EMLA)® to pared plantar warts prior to application of liquid
nitrogen cryotherapy in adults.
Comparing Two Types of Sedation to Gynaecological Patients [Recruiting]
The primary endpoint is to investigate the difference in pain between patients who receive
deep sedation with spontaneous breathing versus patients who receive general anesthesia.
Efficacy, Safety and Tolerability of PSD502 (a Topical Anesthetic) in the Treatment Premature Ejaculation [Recruiting]
The purpose of this study is to evaluate the effectiveness, safety and tolerability of the
investigational drug, PSD502 in subjects with premature ejaculation (PE) The study drug,
PSD02, is a metered dose (measured dose), topical (applied to the skin surface) anesthetic
(numbing) spray containing a mixture of lidocaine and prilocaine. The study drug will be
applied in a spray to the penis prior to intercourse in order to decrease sensitivity in an
attempt to delay ejaculation.
Phase I Study of PSD502 (Lidocaine Prilocaine Spray) Applied to the Glans Penis up to Three Times a Day for 21 Days in Healthy Male Volunteers [Active, not recruiting]