CITANEST PLAIN SUMMARY
Citanest® Plain Dental (prilocaine HCl Injection, USP)
Citanest® Forte Dental (prilocaine and epinephrine Injection, USP)
4% Injection with epinephrine 1:200,000
Citanest Dental (prilocaine HCl) Injection is a sterile, non pyrogenic isotonic solution that contains a local anesthetic agent with or without epinephrine (as bitartrate) and is administered parenterally by injection.
4% Citanest Plain Dental (prilocaine HCl) and 4% Citanest Forte Dental Injections are indicated for the production of local anesthesia in dentistry by nerve block or infiltration techniques. Only accepted procedures for these techniques as described in standard textbooks are recommended.
Media Articles Related to Citanest Plain (Prilocaine Dental)
While under general anesthesia rats' brains may 'remember' odor experienced
Source: Pain / Anesthetics News From Medical News Today [2014.03.19]
Rats' brains may remember odors they were exposed to while deeply anesthetized, suggests research in rats published in the April issue of Anesthesiology.
Anesthesia May Harm Children's Brains
Source: MedicineNet Ear Tubes Specialty [2012.08.20]
Title: Anesthesia May Harm Children's Brains
Category: Health News
Created: 8/20/2012 11:00:00 AM
Last Editorial Review: 8/20/2012 12:00:00 AM
A biomarker for postoperative cognitive dysfunction - aspartic acid in the hippocampus:
Source: Pain / Anesthetics News From Medical News Today [2014.04.01]
Postoperative cognitive dysfunction is the deterioration of cognitive performance after anesthesia and surgery, and manifests as impairments in short-term memory, concentration, language...
Comparable outcomes for outpatient, inpatient orthopaedic surgeries
Source: Arthritis / Rheumatology News From Medical News Today [2014.03.15]
As the effectiveness of anesthesia, pain management and rehabilitation continues to improve, more orthopaedic procedures are being done on an outpatient basis.
Published Studies Related to Citanest Plain (Prilocaine Dental)
Comparison of the efficacy of articaine and prilocaine local anaesthesia for pulpotomy of maxillary and mandibular primary molars. [2011.06]
AIM: The aim of this study was to compare the local anaesthetic efficacy of articaine HCl and prilocaine HCl during an operative procedure after their administration by either mandibular nerve block or maxillary infiltration... CONCLUSION: We concluded that local anaesthesia following mandibular nerve block is more effective than that following maxillary infiltration in 6-8-year-old children. However, the intensity of pain that was experienced by the children during administration of either prilocaine or articaine and some of the dental procedures after their administration were similar.
Anesthetic efficacy of liposomal prilocaine in maxillary infiltration anesthesia. [2011.03]
Animal studies have shown that liposome encapsulation increases prilocaine anesthetic efficacy. This randomized, blind, crossover, three-period study evaluated the anesthetic efficacy of liposome-encapsulated 3% prilocaine, compared to 3% plain prilocaine and 3% prilocaine with 0.03IU/mL felypressin, after a 1.8-mL infiltration in the buccal sulcus of the maxillary right canine, in 32 volunteers...
Spinal anaesthesia for ambulatory arthroscopic surgery of the knee: a comparison of low-dose prilocaine and fentanyl with bupivacaine and fentanyl. [2011.02]
BACKGROUND: Prospective data on the use of prilocaine for ambulatory spinal anaesthesia remain limited. We compared the behaviour and characteristics of subarachnoid block using prilocaine and fentanyl with that of bupivacaine and fentanyl... CONCLUSIONS: The combination of prilocaine and fentanyl is a better alternative to that of low-dose bupivacaine and fentanyl, for spinal anaesthesia in ambulatory arthroscopic knee surgery.
A prospective, double-blinded, randomized, clinical trial comparing the efficacy of 40 mg and 60 mg hyperbaric 2% prilocaine versus 60 mg plain 2% prilocaine for intrathecal anesthesia in ambulatory surgery. [2010.08]
BACKGROUND: In this prospective, double-blind, randomized trial we compared 60 mg and 40 mg of 2% hyperbaric prilocaine with 60 mg of 2% plain prilocaine for spinal anesthesia in terms of sensory block onset in outpatients undergoing elective short-duration (<60 minutes) surgery under spinal anesthesia... CONCLUSIONS: Spinal anesthesia with 60 mg or 40 mg of 2% hyperbaric prilocaine is comparable to 60 mg of 2% plain prilocaine in terms of onset of sensory block at T10. The hyperbaric solution showed faster times to motor block onset and shorter duration of surgical block, suggesting its superiority for the ambulatory setting.
A prospective, double-blinded, randomized, clinical trial comparing the efficacy
of 40 mg and 60 mg hyperbaric 2% prilocaine versus 60 mg plain 2% prilocaine for
intrathecal anesthesia in ambulatory surgery. 
elective short-duration (<60 minutes) surgery under spinal anesthesia... CONCLUSIONS: Spinal anesthesia with 60 mg or 40 mg of 2% hyperbaric prilocaine is
Clinical Trials Related to Citanest Plain (Prilocaine Dental)
Lidocaine-Prilocaine (EMLA) Cream as Analgesia in Hysterosalpingography Practice [Not yet recruiting]
Efficacy Trial of Eutectic Lidocaine/Prilocaine Cream 5% (EMLA) for Analgesia Prior to Cryotherapy of Verrucae Plantaris [Recruiting]
The investigators main purpose is to assess the efficacy of analgesia provide by topical
lidocaine/prilocaine cream 5% (EMLA)® to pared plantar warts prior to application of liquid
nitrogen cryotherapy in adults.
Comparing Two Types of Sedation to Gynaecological Patients [Recruiting]
The primary endpoint is to investigate the difference in pain between patients who receive
deep sedation with spontaneous breathing versus patients who receive general anesthesia.
Efficacy, Safety and Tolerability of PSD502 (a Topical Anesthetic) in the Treatment Premature Ejaculation [Recruiting]
The purpose of this study is to evaluate the effectiveness, safety and tolerability of the
investigational drug, PSD502 in subjects with premature ejaculation (PE) The study drug,
PSD02, is a metered dose (measured dose), topical (applied to the skin surface) anesthetic
(numbing) spray containing a mixture of lidocaine and prilocaine. The study drug will be
applied in a spray to the penis prior to intercourse in order to decrease sensitivity in an
attempt to delay ejaculation.
Phase I Study of PSD502 (Lidocaine Prilocaine Spray) Applied to the Glans Penis up to Three Times a Day for 21 Days in Healthy Male Volunteers [Active, not recruiting]