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Cialis (Tadalafil) - Summary

 
 



CIALIS SUMMARY

CIALIS® (tadalafil), an oral treatment for erectile dysfunction, is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5).

CIALIS is indicated for the treatment of erectile dysfunction.


See all Cialis indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Cialis (Tadalafil)

Pain Specialist Burnout: The Pain Medicine News Report
Source: MedPage Today Neurology [2014.11.12]
(MedPage Today) -- A regular update on what's new in surgery from our friends at Pain Medicine News.

Cialis May Not Prevent Impotence in Men Treated for Prostate Cancer
Source: MedicineNet tadalafil Specialty [2014.04.02]
Title: Cialis May Not Prevent Impotence in Men Treated for Prostate Cancer
Category: Health News
Created: 4/1/2014 4:35:00 PM
Last Editorial Review: 4/2/2014 12:00:00 AM

FDA OKs Impotence Drug Cialis to Treat Enlarged Prostate
Source: MedicineNet tamsulosin Specialty [2011.10.07]
Title: FDA OKs Impotence Drug Cialis to Treat Enlarged Prostate
Category: Health News
Created: 10/7/2011 10:05:00 AM
Last Editorial Review: 10/7/2011 12:00:00 AM

Hepatitis B Virus Testing Gets Short Shrift at VA
Source: MedPage Today Gastroenterology [2014.11.11]
(MedPage Today) -- Better results if treating physician is hepatitis specialist.

The Happy PCP: $400K/Yr and Home in Time for Dinner
Source: MedPage Today Allergy & Immunology [2014.11.07]
(MedPage Today) -- Primary care doc earns a specialist's income without working overtime.

more news >>

Published Studies Related to Cialis (Tadalafil)

Tadalafil once daily and extracorporeal shock wave therapy in the management of patients with Peyronie's disease and erectile dysfunction: results from a prospective randomized trial. [2011.11.15]
Extracorporeal shock wave therapy improves erectile function in patients with Peyronie's disease. However, erectile dysfunction still persists in many cases... In conclusion extracorporeal shock wave therapy plus tadalafil 5 mg once daily may represent a valid conservative strategy for the management of patients with Peyronie's disease and erectile dysfunction.

Efficacy and safety of tadalafil once daily in the treatment of men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia: results of an international randomized, double-blind, placebo-controlled trial. [2011.11]
BACKGROUND: Tadalafil is being investigated for the treatment of lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH-LUTS). OBJECTIVE: To assess efficacy, including onset, and safety of tadalafil on BPH-LUTS and the subject's and clinician's perception of changes in urinary symptoms... CONCLUSIONS: Tadalafil 5mg once daily for 12 wk resulted in a clinically meaningful reduction in total IPSS results as early as 1 wk and achieved statistical significance at 4 wk in men with BPH-LUTS. The adverse event profile was consistent with that previously reported in men with ED. TRIAL REGISTRATION: This clinical trial is registered on the clinicaltrials.gov website (http://www.clinicaltrials.gov). The registration number is NCT00827242. Copyright (c) 2011. Published by Elsevier B.V.

Clinical efficacy of phosphodiesterase-5 inhibitor tadalafil in Eisenmenger syndrome--a randomized, placebo-controlled, double-blind crossover study. [2011.09]
OBJECTIVES: In a randomized double-blind crossover trial, we compared the efficacy of phosphodiesterase-5 (PDE-5) inhibitor tadalafil with placebo in patients of Eisenmenger Syndrome (ES). The primary end point was the change in 6-minute walk test distance (6 MWD). Secondary end points were the effect of the drug on systemic oxygen saturation (SO(2) ), pulmonary vascular resistance (PVR), systemic vascular resistance (SVR), effective pulmonary blood flow (EPBF), and World Health Organization (WHO) functional class. BACKGROUND: ES is a disorder with limited treatment options. Uncontrolled studies have shown PDE-5 inhibitors to be beneficial in patients of ES... CONCLUSION: In this first short-term placebo-controlled trial of tadalafil in patients of ES, the drug was well tolerated and significantly improved exercise capacity, functional class, SO(2) , and pulmonary hemodynamics. (c) 2011 Copyright the Authors. Congenital Heart Disease (c) 2011 Wiley Periodicals, Inc.

Tadalafil versus solifenacin for persistent storage symptoms after prostate surgery in patients with erectile dysfunction: a prospective randomized study. [2011.07]
OBJECTIVES: The occurrence of residual storage symptoms after surgical relief of bladder outlet obstruction as a result of benign prostatic enlargement (BPE) underlines the intricate mechanism involved in lower urinary tract symptoms (LUTS). The aim of the present study was to compare tadalafil with solifenacin in modifying symptoms and uroflowmetric parameters in patients with erectile dysfunction (ED) and residual storage symptoms after prostate surgery... CONCLUSIONS: In patients suffering from ED and storage symptoms after surgical treatment for LUTS-BPE, tadalafil 5mg given once daily for 12weeks provided a comparable improvement in IPSS to solifenacin 5mg given for the same period of time. (c) 2011 The Japanese Urological Association.

Oral tadalafil administration plus low dose vasodilator injection: a novel approach to erection induction for penile color duplex ultrasound. [2011.07]
PURPOSE: We prospectively compared clinical response and penile color duplex ultrasound results of oral tadalafil 20 mg plus low dose intracavernous injection of vasoactive agents with those of intracavernous injection and oral tadalafil 20 mg alone. We also observed the best approach to facilitate penile color duplex ultrasound and that most preferred by patients... CONCLUSIONS: Oral tadalafil plus low dose vasodilator led to a significantly better clinical response than high dose vasodilator. Penile color duplex ultrasound parameters showed no difference between the 2 modes. Thus, this mixed mode emerges as a possible alternative to high dose vasodilator injection. Copyright (c) 2011 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

more studies >>

Clinical Trials Related to Cialis (Tadalafil)

Study of Tadalafil for the Treatment of Diabetic Patients With Symptoms of Upset Stomach and Delayed Stomach Emptying [Completed]
The purposes of this study are to determine whether an experimental drug known as tadalafil can reduce symptoms of dyspepsia (fullness after eating, inability to finish a regular meal, bloating, discomfort or pain in the upper abdomen, belching after meals, nausea, vomiting) in diabetic patients, and/or reduce the amount of time the stomach takes to empty the contents of a standard meal. The safety of tadalafil given once daily for 8 weeks in this population will also be studied.

Study of Tadalafil Once-a Day for 12 Weeks in Men With Signs and Symptoms of Benign Prostatic Hyperplasia [Active, not recruiting]
This is a randomized, double-blind, placebo-controlled, parallel-design, multinational, 12-week study to compare the efficacy, dose response, and safety of tadalafil once a day versus placebo in men with signs and symptoms of benign prostatic hyperplasia, including lower urinary tract symptoms.

PHIRST-1: Tadalafil in the Treatment of Pulmonary Arterial Hypertension [Completed]

Study the Safety and Effectiveness of Tadalafil in Men With Problems Getting or Maintaining an Erection When Taken Prior to Desiring an Erection [Completed]
Study to determine how safe and effective tadalafil is for Japanese men taking it when they need to get and keep an erection.

A Study to Evaluate the Efficacy and Safety of 2.5mg and 5mg Tadalafil Given Once a Day to Men With Erectile Dysfunction [Completed]
This is a multicenter, randomized, double blind, placebo-controlled, parallel design study to evaluate the efficacy and safety of 2. 5mg and 5mg tadalafil taken once daily in men with erectile dysfunction.

more trials >>

Reports of Suspected Cialis (Tadalafil) Side Effects

Drug Ineffective (58)Vision Blurred (41)Headache (28)Visual Impairment (24)Intentional Drug Misuse (23)Myalgia (18)Back Pain (18)Wrong Technique in Drug Usage Process (17)Nausea (14)Blindness (14)more >>


PATIENT REVIEWS / RATINGS / COMMENTS

Based on a total of 7 ratings/reviews, Cialis has an overall score of 8.71. The effectiveness score is 9.43 and the side effect score is 8. The scores are on ten point scale: 10 - best, 1 - worst. Below are selected reviews: the highest, the median and the lowest rated.
 

Cialis review by 59 year old male patient

  Rating
Overall rating:  
Effectiveness:   Highly Effective
Side effects:   No Side Effects
  
Treatment Info
Condition / reason:   impotence
Dosage & duration:   20mg taken 5 days for the period of 5 days
Other conditions:   none
Other drugs taken:   none
  
Reported Results
Benefits:   Cialis taken as prescribed. Had immediate postitive effect as promised, strong, long-lasting erection. Intercourse possible for long period of time- approx 2 days. Had no side-effects at all. Am very satisfied and recommend.
Side effects:   No side effects at all. No headache, gastro-intestinal disturbances or other.
Comments:   Took tadalafil 20 mg in the evening after meal. Had erection approx 30 min later. Erection lasted for 2 days- had never experienced such long-lasting erection.

 

Cialis review by 44 year old male patient

  Rating
Overall rating:  
Effectiveness:   Highly Effective
Side effects:   Mild Side Effects
  
Treatment Info
Condition / reason:   erectile disfunction
Dosage & duration:   5mg (quater of 20mg tab) taken 1-2 times a week for the period of 3 months
Other conditions:   none
Other drugs taken:   none
  
Reported Results
Benefits:   Very quck and long lasting erection. Have been able to have sexual intercorse for 2-3 days no problem. That also had a psychological effect of easing anxiety.
Side effects:   some headache and face flashing
Comments:   5mg was taken 1-2 times a week for several months. That produced very strong and lasting erection in about 20-30 mins. Taking cialis also had the psychological effect of easing anxiety.

 

Cialis review by 53 year old male patient

  Rating
Overall rating:  
Effectiveness:   Highly Effective
Side effects:   Moderate Side Effects
  
Treatment Info
Condition / reason:   ED
Dosage & duration:   20 mg taken as needed for the period of two weeks
Other conditions:   none
Other drugs taken:   none
  
Reported Results
Benefits:   Long lasting erection
Side effects:   achy joints similar to flu symptoms during the next couple of days after taking. Not bad, but definitely annoying. Aspirin helps relieve, but I did not like having to take a pill to counteract another pill. I do not have the same symptom with Viagra.
Comments:   Taken as needed for ED. It is effective in as little as 30 minutes. Time depends if taken on empty stomach or after a meal.

See all Cialis reviews / ratings >>

Page last updated: 2014-11-12

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