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Chlordiazepoxide and Clidinium (Chlordiazepoxide Hydrochloride / Clidinium Bromide) - Side Effects and Adverse Reactions

 
 



ADVERSE REACTIONS

When chlordiazepoxide hydrochloride has been used alone, drowsiness, ataxia and confusion have been reported in some patients, particularly the elderly and debilitated. These effects can be avoided in almost all instances by adjsuting the dosage, and have occasionally been observed at the lower dosage ranges. In a few instances syncope has been reported. Also reported are isolated instances of skin eruptions, edema, nausea and constipation, extrapyramidal symptoms, minor menstrual irregularities, as well as increased and decreased libido. Such side effects have been infrequent and are generally controlled with reduction of dosage. Changes in EEG patterns have been observed in patients during and after chlordiazepoxide hydrochloride treatment. Blood dyscrasias, including agranulocytosia, jaundice and hepatic dysfunction have occasionally been reported during therapy with chlordiazepoxide hydrochloride. When chlordiazepoxide hydrochloride treatment is protracted, periodic blood counts and liver function tests are advisable.  Typical of anticholinergic agents, adverse effects reported with use of Chlordiazepoxide Hydrochloride and Clidinium Bromide Capsules may include dry mouth, blurred vision, urinary hesitancy and constipation. Constipation has occured most often when combined with other spasmolytic agents and/or a restrictive, low residue diet.  Call your doctor for medical advice about side effects. You may report suspected side effects to the FDA at 1-800-FDA-1088.

Drug label data at the top of this Page last updated: 2012-10-18

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