CEREZYME SUMMARY
(Logo) Cerezyme® (imiglucerase for injection)
Cerezyme ® (imiglucerase for injection) is an analogue of the human enzyme (beta)-glucocerebrosidase, produced by recombinant DNA technology. (beta)-Glucocerebrosidase ((beta)-D-glucosyl-N-acylsphingosine glucohydrolase, E.C. 3.2.1.45) is a lysosomal glycoprotein enzyme which catalyzes the hydrolysis of the glycolipid glucocerebroside to glucose and ceramide.
Cerezyme ® (imiglucerase for injection) is indicated for long-term enzyme replacement therapy for pediatric and adult patients with a confirmed diagnosis of Type 1 Gaucher disease that results in one or more of the following conditions:
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anemia
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thrombocytopenia
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bone disease
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hepatomegaly or splenomegaly
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