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Ceprotin (Protein C) - Drug Interactions, Contraindications, Overdosage, etc



No formal drug interaction studies have been conducted.

See WARNINGS AND PRECAUTIONS: Bleeding Episodes for information regarding simultaneous administration of CEPROTIN and tissue plasminogen activator (tPA).

See DOSAGE AND ADMINISTRATION: Initiation of Vitamin K Antagonists for information regarding use of CEPROTIN and vitamin K antagonists.


No symptoms of overdose with CEPROTIN have been reported.

The maximum infusion rate administered in clinical studies were doses of up to 600 IU/kg body weight (BW)/day (150 IU/kg BW every 6 hours) of CEPROTIN. There have been no overdosages of CEPROTIN reported during clinical studies. In long-term prophylactic treatment of doses up to 291.7 IU/kg BW/day, no adverse events were reported.



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