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Cefadroxil (Cefadroxil Hemihydrate) - Side Effects and Adverse Reactions

 
 



ADVERSE REACTIONS

Gastrointestinal

Onset of pseudomembranous colitis symptoms may occur during or after antibiotic treatment (see WARNINGS).  Dyspepsia, nausea and vomiting have been reported rarely. Diarrhea has also occurred.

Hypersensitivity

Allergies (in the form of rash, urticaria, angioedema, and pruritus) have been observed. These reactions usually subsided upon discontinuation of the drug. Anaphylaxis has also been reported.

Other

Other reactions have included hepatic dysfunction including cholestasis and elevations in serum transaminase, genital pruritus, genital moniliasis, vaginitis, moderate transient neutropenia, fever. Agranulocytosis, thrombocytopenia, idiosyncratic hepatic failure, erythema multiforme, Stevens-Johnson syndrome, serum sickness, and arthralgia have been rarely reported.

In addition to the adverse reactions listed above which have been observed in patients treated with cefadroxil, the following adverse reactions and altered laboratory tests have been reported for cephalosporin-class antibiotics:

Toxic epidermal necrolysis, abdominal pain, superinfection, renal dysfunction, toxic nephropathy, aplastic anemia, hemolytic anemia, hemorrhage, prolonged prothrombin time, positive Coombs’ test, increased BUN, increased creatinine, elevated alkaline phosphatase, elevated aspartate aminotransferase (AST), elevated alanine aminotransferase (ALT), elevated bilirubin, elevated LDH, eosinophilia, pancytopenia, neutropenia.

Several cephalosporins have been implicated in triggering seizures, particularly in patients with renal impairment, when the dosage was not reduced (see DOSAGE AND ADMINISTRATION and OVERDOSAGE). If seizures associated with drug therapy occur, the drug should be discontinued. Anticonvulsant therapy can be given if clinically indicated.



REPORTS OF SUSPECTED CEFADROXIL SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Cefadroxil. The information is not vetted and should not be considered as verified clinical evidence.

Possible Cefadroxil side effects / adverse reactions in 38 year old male

Reported by a health professional (non-physician/pharmacist) from Venezuela on 2011-12-08

Patient: 38 year old male

Reactions: Toxic Epidermal Necrolysis

Suspect drug(s):
Cefadroxil
    Indication: Dysphagia

Cefadroxil
    Indication: Odynophagia

Cefadroxil
    Dosage: unk
    Indication: Asthenia

Ibuprofen
    Indication: Dysphagia

Ibuprofen
    Indication: Odynophagia

Ibuprofen
    Dosage: unk
    Indication: Asthenia



Possible Cefadroxil side effects / adverse reactions in 38 year old male

Reported by a physician from Venezuela on 2011-12-08

Patient: 38 year old male

Reactions: Toxic Epidermal Necrolysis

Adverse event resulted in: hospitalization

Suspect drug(s):
Ibuprofen
    Indication: Asthenia

Ibuprofen
    Indication: Dysphagia

Cefadroxil
    Indication: Asthenia

Ibuprofen
    Indication: Odynophagia

Cefadroxil
    Indication: Dysphagia

Cefadroxil
    Indication: Odynophagia



Possible Cefadroxil side effects / adverse reactions in 38 year old male

Reported by a physician from Venezuela on 2011-12-08

Patient: 38 year old male

Reactions: Toxic Epidermal Necrolysis

Adverse event resulted in: hospitalization

Suspect drug(s):
Ibuprofen
    Dosage: unk
    Indication: Odynophagia

Ibuprofen
    Indication: Asthenia

Cefadroxil
    Dosage: unk
    Indication: Odynophagia

Ibuprofen
    Indication: Dysphagia

Cefadroxil
    Indication: Asthenia

Cefadroxil
    Indication: Dysphagia



See index of all Cefadroxil side effect reports >>

Drug label data at the top of this Page last updated: 2013-12-16

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